Chapter

Accomplishments in Cancer Epidemiology

Brian Macmahon

in Textbook of Cancer Epidemiology

Published in print January 2018 | ISBN: 9780190676827
Published online February 2018 | e-ISBN: 9780190676858 | DOI: https://dx.doi.org/10.1093/oso/9780190676827.003.0001
Accomplishments in Cancer Epidemiology

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In his chapter “Accomplishments in Cancer Epidemiology,” Dr. MacMahon summarizes the history of the discipline, particularly the epidemiologic evidence on cigarette smoking, ionizing radiation, occupation, the physical and microbiologic environments, the reproductive experience of women, alcohol, and iatrogenic exposures as their bear on cancer risk in humans. Ionizing radiation as a cause of leukemia and cancer of the skin, breast, lung, and thyroid is discussed in detail, as well as liver cancer and myelogenous leukemia following exposure to the X-ray contrast medium thorotrast. Important occupational carcinogens include arsenic (lung cancer, bladder cancer), asbestos (lung cancer and mesothelioma), benzene (acute myeloid leukemia), chemical dyes (bladder cancer), chromium (lung cancer), nickel (nasal cancer), and vinyl chloride (angiosarcoma in the liver). The chapter ends with a broader overview of the other environmental causes of cancers that are reviewed in detail in the site-specific chapters.

Keywords: history; cancer; epidemiology; environment; smoking; occupation; microbiologic exposure; reproductive experience; alcohol; iatrogenic exposure

Chapter.  19629 words. 

Subjects: Medical Statistics and Methodology ; Public Health and Epidemiology

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