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Inhibitors of bacterial protein synthesis

Roger Finch, Peter Davey, Mark Wilcox and William Irving.

in Antimicrobial Chemotherapy

January 2012; p ublished online November 2013 .

Chapter. Subjects: Pharmacology; Infectious Diseases; Medical Microbiology and Virology. 5191 words.

Chapter 2 covers inhibitors of bacterial protein synthesis with sufficient selectivity to be useful in human therapy, including aminoglycosides, chloramphenicol, tetracyclines, fusidic...

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Laboratory investigations and the treatment of infection

Roger Finch, Peter Davey, Mark Wilcox and William Irving.

in Antimicrobial Chemotherapy

January 2012; p ublished online November 2013 .

Chapter. Subjects: Pharmacology; Infectious Diseases; Medical Microbiology and Virology. 4916 words.

Chapter 12 discusses the basic principles and limitations of using a microbiology laboratory to obtain information on the selection and control of antimicrobial therapy. It is not a...

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Management of HIV infection

Roger Finch, Peter Davey, Mark Wilcox and William Irving.

in Antimicrobial Chemotherapy

January 2012; p ublished online November 2013 .

Chapter. Subjects: Pharmacology; Infectious Diseases; Medical Microbiology and Virology. 2668 words.

Chapter 33 covers the management of HIV infection, including the natural history of HIV infection, what and what to treat with, Treatment failurE (non-compliance and resistance), pregnancy,...

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Outpatient parenteral antimicrobial therapy (OPAT)

Roger Finch, Peter Davey, Mark Wilcox and William Irving.

in Antimicrobial Chemotherapy

January 2012; p ublished online November 2013 .

Chapter. Subjects: Pharmacology; Infectious Diseases; Medical Microbiology and Virology. 1666 words.

Chapter 16 outpatient parenteral antimicrobial therapy (OPAT), including indications, requirements, technology, antibiotics, and monitoring.

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Parasitic diseases

Roger Finch, Peter Davey, Mark Wilcox and William Irving.

in Antimicrobial Chemotherapy

January 2012; p ublished online November 2013 .

Chapter. Subjects: Pharmacology; Infectious Diseases; Medical Microbiology and Virology. 5779 words.

Chapter 35 covers parasitic diseases, including therapeutic difficulties, protozoan infections (malaria, Amoebiasis, Giardiasis, Cryptosporidiosis, African trypanosomiasis, Chagas’ disease,...

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Pharmacokinetic and pharmacodynamic principles

Roger Finch, Peter Davey, Mark Wilcox and William Irving.

in Antimicrobial Chemotherapy

January 2012; p ublished online November 2013 .

Chapter. Subjects: Pharmacology; Infectious Diseases; Medical Microbiology and Virology. 3795 words.

Chapter 14 covers how knowledge of the pharmacokinetic behaviour of a drug is key to defining its therapeutic role. Uniquely among drugs, antibiotics target infecting micro-organisms which...

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Prescribing in children and the elderly

Roger Finch, Peter Davey, Mark Wilcox and William Irving.

in Antimicrobial Chemotherapy

January 2012; p ublished online November 2013 .

Chapter. Subjects: Pharmacology; Infectious Diseases; Medical Microbiology and Virology. 3048 words.

Chapter 15 discusses prescribing in children and the elderly, and how children should not be considered as small adults for the purposes of prescribing. The former practice of scaling down...

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The problem of resistance

Roger Finch, Peter Davey, Mark Wilcox and William Irving.

in Antimicrobial Chemotherapy

January 2012; p ublished online November 2013 .

Chapter. Subjects: Pharmacology; Infectious Diseases; Medical Microbiology and Virology. 3984 words.

Chapter 9 discusses the problem of resistance, including what it is, intrinsic and acquired resistance and their types, Cross-resistance and multiple resistance, clinical problem of drug...

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Respiratory tract infections

Roger Finch, Peter Davey, Mark Wilcox and William Irving.

in Antimicrobial Chemotherapy

January 2012; p ublished online November 2013 .

Chapter. Subjects: Pharmacology; Infectious Diseases; Medical Microbiology and Virology. 5455 words.

Chapter 21 covers respiratory infections, which are caused by viruses, or bacteria, or both. If the illness is entirely viral in origin, an antibiotic will not help. If there is a bacterial...

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Serious bloodstream infections

Roger Finch, Peter Davey, Mark Wilcox and William Irving.

in Antimicrobial Chemotherapy

January 2012; p ublished online November 2013 .

Chapter. Subjects: Pharmacology; Infectious Diseases; Medical Microbiology and Virology. 6113 words.

Chapter 26 covers serious bloodstream infections, including Bacteraemia, assessment of sepsis and the systemic inflammatory response, and infective endocarditis.

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