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abciximab

Overview page. Subjects: Clinical Pharmacology and Therapeutics.

The Fab fragments of a monoclonal antibody directed against the glycoprotein IIb/IIIa receptor on platelets that blocks platelet aggregation. Used as a short-term treatment to prevent...

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Absolute Measurements of Macrophage Migration Inhibitory Factor and Interleukin-1-β mRNA Levels Accurately Predict Treatment Response in Depressed Patients

Annamaria Cattaneo, Clarissa Ferrari, Rudolf Uher, Luisella Bocchio-Chiavetto, Marco Andrea Riva and Carmine M. Pariante.

in International Journal of Neuropsychopharmacology

P ublished online May 2016 .

Journal Article. Subjects: Clinical Pharmacology and Therapeutics; Neurology; Psychiatry; Neuroscience. 8487 words.

Background:

Increased levels of inflammation have been associated with a poorer response to antidepressants in several clinical samples, but these findings...

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acamprosate calcium

Overview page. Subjects: Clinical Pharmacology and Therapeutics.

A drug used, in conjunction with counselling, for the maintenance of sobriety. Patients must already be abstinent at the beginning of treatment. It is administered orally; the most common...

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acarbose

Overview page. Subjects: Clinical Pharmacology and Therapeutics.

(ass-ar-bohz)

an oral hypoglycaemic drug that reduces the breakdown and absorption of carbohydrates in the intestine by blocking the action of an important enzyme (α-glucosidase)...

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ACE inhibitor

Overview page. Subjects: Clinical Pharmacology and Therapeutics.

(ayss)

angiotensin-converting enzyme inhibitor: any one of a group of drugs used in the treatment of raised blood pressure and heart failure. ACE inhibitors act by interfering with...

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ACE inhibitors

Roy S. Gardner, Theresa A. McDonagh and Niki L. Walker.

in Heart Failure

August 2014; p ublished online August 2014 .

Chapter. Subjects: Cardiovascular Medicine; Clinical Pharmacology and Therapeutics. 1419 words.

ACE inhibitors were first introduced because of their vasodilatory properties. It is now understood that the beneficial effects arise from the antagonism of the...

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acebutolol

Overview page. Subjects: Clinical Pharmacology and Therapeutics.

(ass-i-bew-toh-lol)

a beta blocker drug used to treat high blood pressure, angina pectoris, and irregular heart rhythms. It is administered by mouth. Trade name: Sectral.

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Acetaminophen

Chitra Ramasubbu and Anita Gupta.

in Pharmacology in Anesthesia Practice

January 2013; p ublished online September 2013 .

Chapter. Subjects: Anaesthetics; Clinical Pharmacology and Therapeutics. 1257 words.

This chapter discusses acetaminophen, including Clinical Uses /Relevance to Anesthesiology, Pharmacodynamics, Pharmacokinetics, Side Effects/Adverse Reactions, and Dosages/Preparation.

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acetazolamide

Overview page. Subjects: Clinical Pharmacology and Therapeutics.

A carbonic anhydrase inhibitor that is used to treat glaucoma, epileptic seizures, benign intracranial hypertension, altitude sickness, cystinuria, and dural ectasia. TN Diamox.

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Acetylcholine

Leslie L. Iversen, Susan D. Iversen, Floyd E. Bloom and Robert H. Roth.

in Introduction to Neuropsychopharmacology

January 2009; p ublished online September 2013 .

Chapter. Subjects: Clinical Pharmacology and Therapeutics; Pharmacology. 6695 words.

The neurophysiological activity of acetylcholine (ACh) has been known since the early 19th century and its neurotransmitter role since the mid-1920s. With this long history, it is not...

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