Oxford Index Browse

You are looking at 1-10 of 19 items for:

Clinical Medicine x Molecular and Cellular Systems x clear all

Refine by type

Refine by product

 

Diagnosis and investigation

Roger Smith and Paul Wordsworth.

in Oxford Textbook of Clinical and Biochemical Disorders of the Skeleton

March 2016; p ublished online May 2016 .

Chapter. Subjects: Rheumatology; Molecular and Cellular Systems. 21963 words.

This chapter deals with clinical diagnosis and analyses, the use of biochemical and radiological investigations including measurements of bone density. Bone histology is also discussed.

null...

Go to Oxford Medicine Online »  abstract

Ectopic mineralization

Roger Smith and Paul Wordsworth.

in Oxford Textbook of Clinical and Biochemical Disorders of the Skeleton

March 2016; p ublished online May 2016 .

Chapter. Subjects: Rheumatology; Molecular and Cellular Systems. 15785 words.

Ectopic (heterotopic) mineralization has many causes. This chapter deals with calcification in the soft tissues and acquired and inherited extraskeletal ossification. The rare disorder of...

Go to Oxford Medicine Online »  abstract

Ehlers–Danlos syndrome and related disorders

Roger Smith and Paul Wordsworth.

in Oxford Textbook of Clinical and Biochemical Disorders of the Skeleton

March 2016; p ublished online May 2016 .

Chapter. Subjects: Rheumatology; Molecular and Cellular Systems. 10220 words.

Ehlers–Danlos syndrome (EDS) is a group of disorders with soft hyperextensible skin and excessive joint mobility largely due to mutations in the genes for the fibrillin collagens. This...

Go to Oxford Medicine Online »  abstract

Enzyme defects and the skeleton

Roger Smith and Paul Wordsworth.

in Oxford Textbook of Clinical and Biochemical Disorders of the Skeleton

March 2016; p ublished online May 2016 .

Chapter. Subjects: Rheumatology; Molecular and Cellular Systems. 12918 words.

Enzyme gene mutations which have a major effect on the skeleton are homocystinuria, hypophosphatemia, and alkaptonuria. Many other mutations include those of osteoclast acidification...

Go to Oxford Medicine Online »  abstract

Fibrogenesis imperfecta ossium and other disorders of mineralization

Roger Smith and Paul Wordsworth.

in Oxford Textbook of Clinical and Biochemical Disorders of the Skeleton

March 2016; p ublished online May 2016 .

Chapter. Subjects: Rheumatology; Molecular and Cellular Systems. 5044 words.

Fibrogenesis imperfecta ossium is a very rare apparently acquired disorder of collagen, which is non-birefringent and unmineralized. There is extreme bone fragility. The cause is unknown....

Go to Oxford Medicine Online »  abstract

Fibrous dysplasia

Roger Smith and Paul Wordsworth.

in Oxford Textbook of Clinical and Biochemical Disorders of the Skeleton

March 2016; p ublished online May 2016 .

Chapter. Subjects: Rheumatology; Molecular and Cellular Systems. 7716 words.

Fibrous dysplasia is a rare heterogenous disorder resulting from postzygotic activating mutation of the GNAS gene. Its main effect is on the skeleton. According to the distribution of the...

Go to Oxford Medicine Online »  abstract

Introduction

Roger Smith and Paul Wordsworth.

in Oxford Textbook of Clinical and Biochemical Disorders of the Skeleton

March 2016; p ublished online May 2016 .

Chapter. Subjects: Rheumatology; Molecular and Cellular Systems. 2158 words.

This chapter introduces the ‘classic’ and ‘new’ metabolic bone diseases. It deals with their causes and areas of current research.

Go to Oxford Medicine Online »  abstract

Marfan syndrome and related disorders

Roger Smith and Paul Wordsworth.

in Oxford Textbook of Clinical and Biochemical Disorders of the Skeleton

March 2016; p ublished online May 2016 .

Chapter. Subjects: Rheumatology; Molecular and Cellular Systems. 14827 words.

Marfan syndrome is an inherited disorder of connective tissue which involves many tissues. This chapter deals with the causal mutations in fibrillin, with diagnosis, and with changes in the...

Go to Oxford Medicine Online »  abstract

Neoplastic disease and other non-parathyroid causes of hypercalcaemia

Roger Smith and Paul Wordsworth.

in Oxford Textbook of Clinical and Biochemical Disorders of the Skeleton

March 2016; p ublished online May 2016 .

Chapter. Subjects: Rheumatology; Molecular and Cellular Systems. 9520 words.

Malignant disease is the major non-parathyroid cause of hypercalcaemia. Cancer cells can resorb bone directly (as metastases) or indirectly (particularly by the action of PTHrP (PTHLP))....

Go to Oxford Medicine Online »  abstract

Osteogenesis imperfecta and other disorders of low bone density

Roger Smith and Paul Wordsworth.

in Oxford Textbook of Clinical and Biochemical Disorders of the Skeleton

March 2016; p ublished online May 2016 .

Chapter. Subjects: Rheumatology; Molecular and Cellular Systems. 25311 words.

Osteogenesis imperfecta may be regarded as the first of the ‘new’ metabolic bone diseases, largely due to mutations in the genes for type 1 collagen. This chapter deals with the relation...

Go to Oxford Medicine Online »  abstract