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Absolute Measurements of Macrophage Migration Inhibitory Factor and Interleukin-1-β mRNA Levels Accurately Predict Treatment Response in Depressed Patients

Annamaria Cattaneo, Clarissa Ferrari, Rudolf Uher, Luisella Bocchio-Chiavetto, Marco Andrea Riva and Carmine M. Pariante.

in International Journal of Neuropsychopharmacology

P ublished online May 2016 .

Journal Article. Subjects: Clinical Pharmacology and Therapeutics; Neurology; Psychiatry; Neuroscience. 8487 words.

Background:

Increased levels of inflammation have been associated with a poorer response to antidepressants in several clinical samples, but these findings...

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Activation of Protein Kinases and Phosphatases Coupled to Glutamate Receptors Regulates the Phosphorylation State of DARPP32 at Threonine 75 After Repeated Exposure to Cocaine in the Rat Dorsal Striatum in a Ca<sup>2+</sup>-Dependent Manner

Jieun Kim, In Soo Ryu, Su Yeon Seo and Eun Sang Choe.

in International Journal of Neuropsychopharmacology

November 2015; p ublished online July 2015 .

Journal Article. Subjects: Clinical Pharmacology and Therapeutics; Neurology; Psychiatry; Neuroscience. 5785 words.

Background:

Phosphorylation state of dopamine- and cAMP-regulated phosphoprotein, molecular weight 32kDa (DARPP32) is crucial to understand drug-mediated...

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Acute and Chronic Noradrenergic Effects on Cortical Excitability in Healthy Humans

Hsiao-I Kuo, Walter Paulus, Giorgi Batsikadze, Asif Jamil, Min-Fang Kuo and Michael A Nitsche.

in International Journal of Neuropsychopharmacology

P ublished online April 2017 .

Journal Article. Subjects: Clinical Pharmacology and Therapeutics; Neurology; Psychiatry; Neuroscience. 6836 words.

Abstract

Background

Noradrenaline is a major neuromodulator in the central nervous system, and it is involved in...

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Acute Morphine Exposure Increases the Brain Distribution of [<sup>18</sup>F]DPA-714, a PET Biomarker of Glial Activation in Nonhuman Primates

Sylvain Auvity, Wadad Saba, Sébastien Goutal, Claire Leroy, Irène Buvat, Jérôme Cayla, Fabien Caillé, Michel Bottlaender, Salvatore Cisternino and Nicolas Tournier.

in International Journal of Neuropsychopharmacology

P ublished online August 2016 .

Journal Article. Subjects: Clinical Pharmacology and Therapeutics; Neurology; Psychiatry; Neuroscience. 3121 words.

Abstract

Background:

The neuroinflammatory response to morphine exposure modulates its antinociceptive effects,...

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Adolescent Alcohol Exposure-Induced Changes in Alpha-Melanocyte Stimulating Hormone and Neuropeptide Y Pathways via Histone Acetylation in the Brain During Adulthood

Dadasaheb M Kokare, Evan J Kyzar, Huaibo Zhang, Amul J Sakharkar and Subhash C Pandey.

in International Journal of Neuropsychopharmacology

P ublished online May 2017 .

Journal Article. Subjects: Clinical Pharmacology and Therapeutics; Neurology; Psychiatry; Neuroscience. 7433 words.

Abstract

Background

Adolescent intermittent ethanol exposure causes long-lasting alterations in brain epigenetic...

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Affinity States of Striatal Dopamine D2 Receptors in Antipsychotic-Free Patients with Schizophrenia

Manabu Kubota, Tomohisa Nagashima, Harumasa Takano, Fumitoshi Kodaka, Hironobu Fujiwara, Keisuke Takahata, Sho Moriguchi, Yasuyuki Kimura, Makoto Higuchi, Yoshiro Okubo, Hidehiko Takahashi, Hiroshi Ito and Tetsuya Suhara.

in International Journal of Neuropsychopharmacology

P ublished online July 2017 .

Journal Article. Subjects: Clinical Pharmacology and Therapeutics; Neurology; Psychiatry; Neuroscience. 4890 words.

Abstract

Background

Dopamine D2 receptors are reported to have high-affinity (D2High) and low-affinity (D2Low)...

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Agomelatine Increases BDNF Serum Levels in Depressed Patients in Correlation with the Improvement of Depressive Symptoms

Giovanni Martinotti, Mauro Pettorruso, Domenico De Berardis, Paola Annunziata Varasano, Gabriella Lucidi Pressanti, Valeria De Remigis, Alessandro Valchera, Valerio Ricci, Marco Di Nicola, Luigi Janiri, Giovanni Biggio and Massimo Di Giannantonio.

in International Journal of Neuropsychopharmacology

P ublished online January 2016 .

Journal Article. Subjects: Clinical Pharmacology and Therapeutics; Neurology; Psychiatry; Neuroscience. 3604 words.

Background:

Agomelatine modulates brain-derived neurotrophic factor expression via its interaction with melatonergic and serotonergic receptors and has...

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Agonist and Antagonist Effects of Aripiprazole on D<sub>2</sub>-Like Receptors Controlling Rat Brain Dopamine Synthesis Depend on the Dopaminergic Tone

Guo Fen Ma, Noora Raivio, Josefa Sabrià and Jordi Ortiz.

in International Journal of Neuropsychopharmacology

P ublished online January 2015 .

Journal Article. Subjects: Clinical Pharmacology and Therapeutics; Neurology; Psychiatry; Neuroscience. 6522 words.

Background:

The atypical antipsychotic drug aripiprazole binds with high affinity to a number of G protein coupled receptors, including dopamine D2 receptor...

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Amygdala-Hippocampal Phospholipase D (PLD) Signaling As Novel Mechanism of Cocaine-Environment Maladaptive Conditioned Responses

Balaji Krishnan.

in International Journal of Neuropsychopharmacology

P ublished online January 2016 .

Journal Article. Subjects: Clinical Pharmacology and Therapeutics; Neurology; Psychiatry; Neuroscience. 7923 words.

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Antidepressant Effects of Abscisic Acid Mediated by the Downregulation of Corticotrophin-Releasing Hormone Gene Expression in Rats

Cong-Cong Qi, Zhi Zhang, Hui Fang, Ji Liu, Nan Zhou, Jin-Fang Ge, Fang-Han Chen, Cheng-Bin Xiang and Jiang-Ning Zhou.

in International Journal of Neuropsychopharmacology

P ublished online December 2014 .

Journal Article. Subjects: Clinical Pharmacology and Therapeutics; Neurology; Psychiatry; Neuroscience. 6747 words.

Background:

Corticotrophin-releasing hormone (CRH) is considered to be the central driving force of the hypothalamic-pituitary-adrenal axis, which plays a...

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