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Adult Brainstem Gliomas With H3K27M Mutation: Radiology, Pathology, and Prognosis

Elena V Daoud, Veena Rajaram, Chunyu Cai, Robert J Oberle, Gregory R Martin, Jack M Raisanen, Charles L White, Chan Foong, Bruce E Mickey, Edward Pan and Kimmo J Hatanpaa.

in Journal of Neuropathology & Experimental Neurology

April 2018; p ublished online February 2018 .

Journal Article. Subjects: Neurology; Clinical Neuroscience; Pathology; Histopathology. 4782 words.

Abstract

Adult brainstem gliomas are difficult to classify based on radiologic and histologic features. A K27M mutation in histone 3 has been described to...

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American Association of Neuropathologists, Inc. Abstracts of the 94th Annual Meeting, June 7–10, 2018 Louisville, Kentucky

in Journal of Neuropathology & Experimental Neurology

June 2018; p ublished online May 2018 .

Journal Article. Subjects: Neurology; Clinical Neuroscience; Pathology; Histopathology. 67812 words.

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Autobiography Series: In Search of Knowledge and Joy: My Life as a Neuropathologist

Samuel K Ludwin.

in Journal of Neuropathology & Experimental Neurology

February 2018; p ublished online December 2017 .

Journal Article. Subjects: Neurology; Clinical Neuroscience; Pathology; Histopathology. 8062 words.

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Central Nervous System Germinomas Express Programmed Death Ligand 1

Miriam E Wildeman, Matthew J Shepard, Edward H Oldfield and M Beatriz S Lopes.

in Journal of Neuropathology & Experimental Neurology

April 2018; p ublished online February 2018 .

Journal Article. Subjects: Neurology; Clinical Neuroscience; Pathology; Histopathology. 2769 words.

Abstract

Immunomodulation and tumor-induced tolerance is one of the central mechanisms in the oncogenesis of malignant and benign neoplasms. While numerous...

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Characterization of the Nile Grass Rat as a Unique Model for Type 2 Diabetic Polyneuropathy

Jyoti Singh, Muhammad Saad Yousuf, Kelvin E Jones, Paige T M Shelemey, Twinkle Joy, Haecy Macandili, Bradley J Kerr, Douglas W Zochodne, Yves Sauvé, Klaus Ballanyi and Christine A Webber.

in Journal of Neuropathology & Experimental Neurology

June 2018; p ublished online April 2018 .

Journal Article. Subjects: Neurology; Clinical Neuroscience; Pathology; Histopathology. 5364 words.

Abstract

Type 2 diabetes (T2D) has reached pandemic proportions worldwide. Almost half of T2D patients suffer from polyneuropathy that can present as...

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Combination Treatment With Exogenous GDNF and Fetal Spinal Cord Cells Results in Better Motoneuron Survival and Functional Recovery After Avulsion Injury With Delayed Root Reimplantation

Carolin Ruven, Smaranda-Ruxandra Badea, Wai-Man Wong and Wutian Wu.

in Journal of Neuropathology & Experimental Neurology

April 2018; p ublished online February 2018 .

Journal Article. Subjects: Neurology; Clinical Neuroscience; Pathology; Histopathology. 11076 words.

Abstract

When spinal roots are torn off from the spinal cord, both the peripheral and central nervous system get damaged. As the motoneurons lose their axons,...

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Combined Pathologies in FTLD-TDP Types A and C

Tamar Gefen, Saman S Ahmadian, Qinwen Mao, Garam Kim, Mustafa Seckin, Borna Bonakdarpour, Eliana Marisa Ramos, Giovanni Coppola, Rosa Rademakers, Emily Rogalski, Alfred Rademaker, Sandra Weintraub, M -Marsel Mesulam, Changiz Geula and Eileen H Bigio.

in Journal of Neuropathology & Experimental Neurology

May 2018; p ublished online March 2018 .

Journal Article. Subjects: Neurology; Clinical Neuroscience; Pathology; Histopathology. 4728 words.

Abstract

This study investigated the presence of combined pathologies in a large cohort of autopsies that show a primary pathologic diagnosis of phosphorylated...

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Comparative Cytogenetic Analysis of Dog and Human Choroid Plexus Tumors Defines Syntenic Regions of Genomic Loss

Devin Ancona, Dan York, Robert J Higgins, Danika Bannasch and Peter J Dickinson.

in Journal of Neuropathology & Experimental Neurology

May 2018; p ublished online March 2018 .

Journal Article. Subjects: Neurology; Clinical Neuroscience; Pathology; Histopathology. 3270 words.

Abstract

Choroid plexus tumors (CPTs) occur spontaneously in humans and dogs providing an opportunity for comparative cross species analysis of common tumor...

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Diffuse Astrocytoma, IDH-Wildtype: A Dissolving Diagnosis

Martin Hasselblatt, Mohammed Jaber, David Reuss, Oliver Grauer, Annkatrin Bibo, Stephanie Terwey, Uta Schick, Heinrich Ebel, Thomas Niederstadt, Walter Stummer, Andreas von Deimling and Werner Paulus.

in Journal of Neuropathology & Experimental Neurology

June 2018; p ublished online February 2018 .

Journal Article. Subjects: Neurology; Clinical Neuroscience; Pathology; Histopathology. 1658 words.

Abstract

The histological and molecular features and even the mere existence of diffuse astrocytoma, IDH-wildtype, remain unclear. We therefore examined 212...

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Discrepancy Between Low Levels of mTOR Activity and High Levels of P-S6 in Primary Central Nervous System Lymphoma May Be Explained by PAS Domain-Containing Serine/Threonine-Protein Kinase-Mediated Phosphorylation

Dóra Marosvári, Noémi Nagy, Csilla Kriston, Beáta Deák, Melinda Hajdu, Csaba Bödör, Irén Csala, Attila G Bagó, Zoltán Szállási, Anna Sebestyén and Lilla Reiniger.

in Journal of Neuropathology & Experimental Neurology

April 2018; p ublished online January 2018 .

Journal Article. Subjects: Neurology; Clinical Neuroscience; Pathology; Histopathology. 3563 words.

Abstract

The primary aim of this study was to determine mTOR-pathway activity in primary central nervous system lymphoma (PCNSL), which could be a potential...

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