Abatacept (CTLA-4Ig) treatment reduces T cell apoptosis and regulatory T cell suppression in patients with rheumatoid arthritis
in Rheumatology
April 2016; p ublished online December 2015 .
Journal Article. Subjects: Rheumatology; Pharmacology. 5526 words.
Objective. Abatacept (CTLA-4Ig) blocks CD28-mediated T cell activation by binding to the costimulatory B7 ligands CD80/CD86 on antigen presenting cells. Costimulatory...
Biologic efficacy optimization—a step towards personalized medicine
in Rheumatology
May 2016; p ublished online September 2015 .
Journal Article. Subjects: Rheumatology; Pharmacology. 6147 words.
This following is a review of the factors that influence the outcome of biologic agents in the treatment of adult RA and, when synthesized into the clinical decision-making process, enhance...
BSR and BHPR guideline on prescribing drugs in pregnancy and breastfeeding—Part I: standard and biologic disease modifying anti-rheumatic drugs and corticosteroids
in Rheumatology
September 2016; p ublished online January 2016 .
Journal Article. Subjects: Pharmacology; Rheumatology; Obstetrics. 2259 words.
BSR and BHPR guideline on prescribing drugs in pregnancy and breastfeeding—Part II: analgesics and other drugs used in rheumatology practice
in Rheumatology
September 2016; p ublished online January 2016 .
Journal Article. Subjects: Rheumatology; Obstetrics; Pharmacology. 2377 words.
Calprotectin more accurately discriminates the disease status of rheumatoid arthritis patients receiving tocilizumab than acute phase reactants
in Rheumatology
December 2015; p ublished online August 2015 .
Journal Article. Subjects: Rheumatology; Pharmacology. 2579 words.
Objective. To compare the accuracy of serum calprotectin levels, CRP and ESR in stratifying disease activity in RA patients receiving tocilizumab (TCZ).
M...
Can the publication of guidelines change the management of early rheumatoid arthritis? An interrupted time series analysis from the United Kingdom
in Rheumatology
December 2015; p ublished online August 2015 .
Journal Article. Subjects: Rheumatology; Pharmacology. 2741 words.
Objective. To assess whether publication of national treatment guidelines improved the management of early RA in the UK.
Methods. Incident diagnoses of RA...
Cardiovascular risk with NSAIDs in rheumatoid arthritis: an analysis using routinely collected data
in Rheumatology
April 2016; p ublished online November 2015 .
Journal Article. Subjects: Rheumatology; Pharmacology. 1049 words.
Do low-dose anti-TNF regimens have a role in patients with ankylosing spondylitis?
in Rheumatology
May 2016; p ublished online December 2015 .
Journal Article. Subjects: Rheumatology; Pharmacology. 2035 words.
Drug trough levels predict therapeutic responses to dose reduction of adalimumab for rheumatoid arthritis patients during 24 weeks of follow-up
in Rheumatology
January 2016; p ublished online August 2015 .
Journal Article. Subjects: Rheumatology; Pharmacology. 3039 words.
Objective. To evaluate the impact of adalimumab (ADA) dose-halving on therapeutic responses and drug levels, the differences in drug levels among patients with different...
Drugs used in rheumatology
in Oxford Handbook of Rheumatology
P ublished online September 2011 .
Chapter. Subjects: Rheumatology; Pharmacology. 11891 words.
