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Adult Brainstem Gliomas With H3K27M Mutation: Radiology, Pathology, and Prognosis

Elena V Daoud, Veena Rajaram, Chunyu Cai, Robert J Oberle, Gregory R Martin, Jack M Raisanen, Charles L White, Chan Foong, Bruce E Mickey, Edward Pan and Kimmo J Hatanpaa.

in Journal of Neuropathology & Experimental Neurology

April 2018; p ublished online February 2018 .

Journal Article. Subjects: Neurology; Clinical Neuroscience; Pathology; Histopathology. 4782 words.

Abstract

Adult brainstem gliomas are difficult to classify based on radiologic and histologic features. A K27M mutation in histone 3 has been described to...

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American Association of Neuropathologists, Inc. Abstracts of the 94th Annual Meeting, June 7–10, 2018 Louisville, Kentucky

in Journal of Neuropathology & Experimental Neurology

June 2018; p ublished online May 2018 .

Journal Article. Subjects: Neurology; Clinical Neuroscience; Pathology; Histopathology. 67812 words.

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Amyotrophic Lateral Sclerosis and the Frontotemporal Dementias

Edited by Michael J. Strong.

October 2012; p ublished online November 2012 .

Book. Subjects: Neurology; Pathology; Clinical Genetics. 432 pages.

This resource summarizes the advances in our understanding of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), as well as the potential relationship between the two.

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Autobiography Series: In Search of Knowledge and Joy: My Life as a Neuropathologist

Samuel K Ludwin.

in Journal of Neuropathology & Experimental Neurology

February 2018; p ublished online December 2017 .

Journal Article. Subjects: Neurology; Clinical Neuroscience; Pathology; Histopathology. 8062 words.

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Autoimmune and paraneoplastic autonomic neuropathies

Steven Vernino and Angela Vincent.

in Autonomic Failure

May 2013; p ublished online July 2013 .

Chapter. Subjects: Neurology; Immunology. 8065 words.

Key points

Cancer patients may have autonomic dysfunction due to direct effects of the malignancy or due to remote effects mediated by the immune system. - Acute or subacute autonomic...

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Autonomic Failure

Edited by Christopher J. Mathias and Sir Roger Bannister.

May 2013; p ublished online July 2013 .

Book. Subjects: Neurology; Anatomy; Urology; Respiratory Medicine and Pulmonology; Gastroenterology; Nephrology; Pain Medicine; Cardiovascular Medicine; Ophthalmology; Reproductive Medicine; Immunology; Endocrinology and Diabetes; Paediatrics; Geriatric Medicine; Anaesthetics; Pharmacology; Medical Toxicology; Surgery. 928 pages.

This new edition of Autonomic Failure features numerous new chapters and makes diagnosis increasingly precise by fully evaluating the underlying anatomical and functional deficits, thereby...

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Central Nervous System Germinomas Express Programmed Death Ligand 1

Miriam E Wildeman, Matthew J Shepard, Edward H Oldfield and M Beatriz S Lopes.

in Journal of Neuropathology & Experimental Neurology

April 2018; p ublished online February 2018 .

Journal Article. Subjects: Neurology; Clinical Neuroscience; Pathology; Histopathology. 2769 words.

Abstract

Immunomodulation and tumor-induced tolerance is one of the central mechanisms in the oncogenesis of malignant and benign neoplasms. While numerous...

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Characterization of the Nile Grass Rat as a Unique Model for Type 2 Diabetic Polyneuropathy

Jyoti Singh, Muhammad Saad Yousuf, Kelvin E Jones, Paige T M Shelemey, Twinkle Joy, Haecy Macandili, Bradley J Kerr, Douglas W Zochodne, Yves Sauvé, Klaus Ballanyi and Christine A Webber.

in Journal of Neuropathology & Experimental Neurology

June 2018; p ublished online April 2018 .

Journal Article. Subjects: Neurology; Clinical Neuroscience; Pathology; Histopathology. 5364 words.

Abstract

Type 2 diabetes (T2D) has reached pandemic proportions worldwide. Almost half of T2D patients suffer from polyneuropathy that can present as...

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Combination Treatment With Exogenous GDNF and Fetal Spinal Cord Cells Results in Better Motoneuron Survival and Functional Recovery After Avulsion Injury With Delayed Root Reimplantation

Carolin Ruven, Smaranda-Ruxandra Badea, Wai-Man Wong and Wutian Wu.

in Journal of Neuropathology & Experimental Neurology

April 2018; p ublished online February 2018 .

Journal Article. Subjects: Neurology; Clinical Neuroscience; Pathology; Histopathology. 11076 words.

Abstract

When spinal roots are torn off from the spinal cord, both the peripheral and central nervous system get damaged. As the motoneurons lose their axons,...

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Combined Pathologies in FTLD-TDP Types A and C

Tamar Gefen, Saman S Ahmadian, Qinwen Mao, Garam Kim, Mustafa Seckin, Borna Bonakdarpour, Eliana Marisa Ramos, Giovanni Coppola, Rosa Rademakers, Emily Rogalski, Alfred Rademaker, Sandra Weintraub, M -Marsel Mesulam, Changiz Geula and Eileen H Bigio.

in Journal of Neuropathology & Experimental Neurology

May 2018; p ublished online March 2018 .

Journal Article. Subjects: Neurology; Clinical Neuroscience; Pathology; Histopathology. 4728 words.

Abstract

This study investigated the presence of combined pathologies in a large cohort of autopsies that show a primary pathologic diagnosis of phosphorylated...

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