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Science and Mathematics x Clinical Pharmacology and Therapeutics x Cardiothoracic Surgery x clear all

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Cardioplegic arrest induces apoptosis signal-pathway in myocardial endothelial cells and cardiac myocytes

Uwe M. Fischer, Oliver Klass, Ulrike Stock, Jerry Easo, Hans J. Geissler, Juergen H. Fischer, Wilhelm Bloch and Uwe Mehlhorn.

in European Journal of Cardio-Thoracic Surgery

June 2003; p ublished online June 2003 .

Journal Article. Subjects: Cardiothoracic Surgery; Clinical Pharmacology and Therapeutics; Cardiovascular Medicine; Molecular and Cell Biology; Molecular Biology and Genetics. 3332 words.

Objective: Myocardial ischemia–reperfusion is associated with free radical-mediated injury and may be involved in cardiac apoptosis. The purpose of our study was to investigate...

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The effects of preoperative statins on the incidence of postoperative acute kidney injury in patients undergoing cardiac surgeries

Mohammad Hassan Nemati and Behrooz Astaneh.

in Interactive CardioVascular and Thoracic Surgery

October 2015; p ublished online July 2015 .

Journal Article. Subjects: Clinical Pharmacology and Therapeutics; Professional Development in Medicine; Molecular and Cell Biology; Cardiovascular Medicine; Cardiothoracic Surgery; Molecular Biology and Genetics. 3742 words.

OBJECTIVES

Recent evidence has emphasized multifunctional therapeutic effects of statins on renal protection after cardiac surgeries. We aimed to assess the...

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Effects of purified poloxamer 407 gel on vascular occlusion and the coronary endothelium

Munir Boodhwani, Jun Feng, Shigetoshi Mieno, Basel Ramlawi, Neel Sodha, Richard Clements and Frank W. Sellke.

in European Journal of Cardio-Thoracic Surgery

May 2006; p ublished online May 2006 .

Journal Article. Subjects: Cardiothoracic Surgery; Molecular and Cell Biology; Cardiovascular Medicine; Surgery; Clinical Pharmacology and Therapeutics; Molecular Biology and Genetics. 3889 words.

Objective: Vascular occlusion during off-pump coronary surgery often results in sub-optimal visualization and endothelial damage of the target vessel. We have previously...

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Enhancement of Na<sup>+</sup>,K<sup>+</sup>-ATPase and Ca<sup>2+</sup>-ATPase activities in multi-cycle ischemic preconditioning in rabbit hearts

Toshihiro Yorozuya, Naoto Adachi, Kentaro Dote, Kazuo Nakanishi, Yasushi Takasaki and Tatsuru Arai.

in European Journal of Cardio-Thoracic Surgery

November 2004; p ublished online November 2004 .

Journal Article. Subjects: Cardiothoracic Surgery; Molecular and Cell Biology; Cardiovascular Medicine; Clinical Pharmacology and Therapeutics; History of Medicine; Molecular Biology and Genetics. 3517 words.

Objective: Ischemic preconditioning (IP) has been shown to attenuate intracellular Na+ accumulation and Ca2+ overload during ischemia and reperfusion, both of which are closely...

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Mitochondrial DNA deletions in coronary artery bypass grafting patients

Sidney Levitsky, Jari Laurikka, Robert D. Stewart, Christian T. Campos, Steven J. Lahey and James D. McCully.

in European Journal of Cardio-Thoracic Surgery

November 2003; p ublished online November 2003 .

Journal Article. Subjects: Anatomy; Cardiothoracic Surgery; Molecular and Cell Biology; Cardiovascular Medicine; Clinical Pharmacology and Therapeutics; History of Medicine; Molecular Biology and Genetics. 4093 words.

Objective: Mitochondrial DNA (mitoDNA) deletions have been shown to increase with aging and ischemia and have been suggested to contribute to myocardial dysfunction. The...

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Mitral valve repair of isolated posterior leaflet prolapse: resect or respect?

Christos Tourmousoglou, Spiros Lalos and Dimitrios Dougenis.

in Interactive CardioVascular and Thoracic Surgery

December 2014; p ublished online September 2014 .

Journal Article. Subjects: Cardiothoracic Anaesthesia; Cardiothoracic Surgery; Professional Development in Medicine; Molecular and Cell Biology; Surgical Oncology; Cardiovascular Medicine; Gastroenterology; Clinical Pharmacology and Therapeutics; Molecular Biology and Genetics. 4479 words.

A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was whether it is best in a patient with posterior leaflet prolapse to resect...

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Restoration of sarcoplasmic reticulum protein level by thyroid hormone contributes to partial improvement of myocardial function, but not to glucose metabolism in an early failing heart

Masahito Minakawa, Koh Takeuchi, Kazuo Ito, Takao Tsushima, Kozo Fukui, Shunichi Takaya and Ikuo Fukuda.

in European Journal of Cardio-Thoracic Surgery

October 2003; p ublished online October 2003 .

Journal Article. Subjects: Cardiothoracic Surgery; Molecular and Cell Biology; Cardiovascular Medicine; Surgery; Clinical Pharmacology and Therapeutics; Molecular Biology and Genetics. 5091 words.

Objective: In heart failure, sarcoplasmic reticulum Ca2+-ATPase (SERCA2) activity is decreased, resulting in abnormal Ca2+ handling and contractile dysfunction. We have...

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RNase1 as a potential mediator of remote ischaemic preconditioning for cardioprotection

Hector A. Cabrera-Fuentes, Bernd Niemann, Philippe Grieshaber, Matthias Wollbrueck, Johannes Gehron, Klaus T. Preissner and Andreas Böning.

in European Journal of Cardio-Thoracic Surgery

November 2015; p ublished online January 2015 .

Journal Article. Subjects: Cardiothoracic Surgery; Clinical Pharmacology and Therapeutics; Cardiovascular Medicine; Molecular and Cell Biology; Molecular Biology and Genetics. 3961 words.

OBJECTIVES

Remote ischaemic preconditioning (RIPC) is a non-invasive and virtually cost-free strategy for protecting the heart against acute...

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Vasomotor dysfunction after cardiac surgery

Marc Ruel, Tanveer A. Khan, Pierre Voisine, Cesario Bianchi and Frank W. Sellke.

in European Journal of Cardio-Thoracic Surgery

November 2004; p ublished online November 2004 .

Journal Article. Subjects: Cardiothoracic Surgery; Clinical Pharmacology and Therapeutics; Cardiovascular Medicine; Molecular and Cell Biology; Molecular Biology and Genetics. 7330 words.

Cardiopulmonary bypass and cardioplegic arrest, which allow for support of the circulation and stabilization of the heart during cardiac procedures, are still used for the vast majority of...

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Who might benefit from early aspirin after coronary artery surgery?

Philemon Gukop, Nadav Gutman, Rajdeep Bilkhu and Georgios T. Karapanagiotidis.

in Interactive CardioVascular and Thoracic Surgery

September 2014; p ublished online May 2014 .

Journal Article. Subjects: Professional Development in Medicine; Cardiothoracic Surgery; Clinical Pharmacology and Therapeutics; Cardiovascular Medicine; Molecular Biology and Genetics; Molecular and Cell Biology. 3301 words.

A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was whether early administration of aspirin might optimize vein graft...

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