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3.9 Å structure of the nucleosome core particle determined by phase-plate cryo-EM

Eugene Y.D. Chua, Vinod K. Vogirala, Oviya Inian, Andrew S.W. Wong, Lars Nordenskiöld, Juergen M. Plitzko, Radostin Danev and Sara Sandin.

in Nucleic Acids Research

September 2016; p ublished online August 2016 .

Journal Article. Subjects: Molecular and Cell Biology; Genetics and Genomics; Research Methods in Life Sciences; Proteins; Molecular Biology and Genetics. 3716 words.

The Volta phase plate is a recently developed electron cryo-microscopy (cryo-EM) device that enables contrast enhancement of biological samples. Here we have evaluated the potential of...

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The A1298C Mutation in Methylenetetrahydrofolate Reductase Gene and Its Association With Idiopathic Venous Thrombosis in an Iranian Population

Mohammad Soleyman Soltanpour, Zahra Soheili, Ali Akbar Pourfathollah, Shahram Samiei, Reza Meshkani, Ali Asghar Kiani, Safa Majid, Zahra Ataei and Mahnaz Kavari.

in Laboratory Medicine

April 2011; p ublished online October 2015 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics; Molecular and Cell Biology; Molecular Biology and Genetics. 2806 words.

Background:

Venous thrombosis (VT) is an important cause of mortality and morbidity resulting from acquired and inherited factors. The A1298C mutation of the...

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ABA Regulates Subcellular Redistribution of OsABI-LIKE2, a Negative Regulator in ABA Signaling, to Control Root Architecture and Drought Resistance in <i>Oryza sativa</i>

Chengxiang Li, Hongyun Shen, Tao Wang and Xuelu Wang.

in Plant and Cell Physiology

December 2015; p ublished online October 2015 .

Journal Article. Subjects: Molecular Biology and Genetics; Biotechnology; Biochemistry; Bioinformatics and Computational Biology; Molecular and Cell Biology; Plant Sciences and Forestry; Plant Physiology. 8295 words.

The phytohormone ABA is a key stress signal in plants. Although the identification of ABA receptors led to significant progress in understanding the Arabidopsis ABA signaling pathway, there...

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ABCA1 and ABCG1 Expression in the Small Intestine of Type 2 Diabetic Rats

Juanya Lou, Huali Zhou, Chengjiang Li, Lingling Hu, Xunliang Lu, Jun Li, Hongtian Yao, Wenpeng Li, Xinxin Zhang and Mingzhi Xu.

in Laboratory Medicine

February 2014; p ublished online September 2015 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics; Molecular and Cell Biology; Molecular Biology and Genetics. 3625 words.

Objective

Inflammation of the small intestine may occur in type 2 diabetes. This study aimed to investigate whether ATP-binding cassette transporter A1...

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Abscisic Acid Participates in the Control of Cell Cycle Initiation Through Heme Homeostasis in the Unicellular Red Alga <i>Cyanidioschyzon merolae</i>

Yuki Kobayashi, Hiroyuki Ando, Mitsumasa Hanaoka and Kan Tanaka.

in Plant and Cell Physiology

May 2016; p ublished online April 2016 .

Journal Article. Subjects: Molecular Biology and Genetics; Biotechnology; Biochemistry; Bioinformatics and Computational Biology; Molecular and Cell Biology; Plant Sciences and Forestry; Plant Physiology. 5053 words.

ABA is a phytohormone that is synthesized in response to abiotic stresses and other environmental changes, inducing various physiological responses. While ABA has been found in unicellular...

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Absence of TLR4 Asp299Gly and Thr399Ile Polymorphisms in Chinese Han Population With Type 2 Diabetes

Peng-bin Lai, Lei Zhang, Sun-jie Yan and Li-yong Yang.

in Laboratory Medicine

September 2010; p ublished online October 2015 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics; Molecular and Cell Biology; Molecular Biology and Genetics. 1715 words.

Objective:

This study was performed to detect the association between the Asp299Gly and Thr399Ile polymorphisms of the TLR4 gene and type 2 diabetes in the...

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Absolute Quantitation of Different Genotypes of Hepatitis C Virus RNA in Clinical Samples by a Modified Real-Time PCR Method

Karina del Carmen Trujillo-Murillo, Diana Cristina Pérez-Ibave, Clara Patricia Ríos-Ibarra, Eda Guadalupe Ramirez-Valles, Ana Rosa Rincón-Sánchez and Ana María Rivas-Estilla.

in Laboratory Medicine

June 2011; p ublished online October 2015 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics; Molecular and Cell Biology; Molecular Biology and Genetics. 2425 words.

Background:

Our aim was to develop a quantitative real-time polymerase chain reaction (qPCR) assay for the quantitation of hepatitis C virus (HCV) RNA...

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Abundance of BER-related proteins depends on cell proliferation status and the presence of DNA polymerase β

Mizuki Yamamoto, Ryohei Yamamoto, Shigeo Takenaka, Satoshi Matsuyama and Kihei Kubo.

in Journal of Radiation Research

July 2015; p ublished online March 2015 .

Journal Article. Subjects: Clinical Genetics; Molecular Biology and Genetics; Epidemiology; Radiology; Nuclear Chemistry, Photochemistry, and Radiation. 4559 words.

In mammalian cells, murine N-methylpurine DNA glycosylase (MPG) removes bases damaged spontaneously or by chemical agents through the process called base excision repair (BER). In this...

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Accurate <i>ab initio</i> prediction of NMR chemical shifts of nucleic acids and nucleic acids/protein complexes

Andrea Victora, Heiko M. Möller and Thomas E. Exner.

in Nucleic Acids Research

December 2014; p ublished online November 2014 .

Journal Article. Subjects: Molecular and Cell Biology; Proteins; Molecular Biology and Genetics. 7813 words.

NMR chemical shift predictions based on empirical methods are nowadays indispensable tools during resonance assignment and 3D structure calculation of proteins. However, owing to the very...

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The <i>ACE</i> I/D Polymorphism in US Adults: Limited Evidence of Association With Hypertension-Related Traits and Sex-Specific Effects by Race/Ethnicity

Renée M. Ned, Ajay Yesupriya, Giuseppina Imperatore, Diane T. Smelser, Ramal Moonesinghe, Man-Huei Chang and Nicole F. Dowling.

in American Journal of Hypertension

February 2012; p ublished online February 2012 .

Journal Article. Subjects: Genetics and Genomics; Molecular Biology and Genetics. 4427 words.

Background:

The insertion/deletion (I/D) variant (rs4646994) of the angiotensin I-converting enzyme (ACE) gene is one of the most studied polymorphisms in...

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