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A 21st Century Paradigm for Evaluating the Health Hazards of Nanoscale Materials?

Nigel J. Walker and John R. Bucher.

in Toxicological Sciences

August 2009; p ublished online May 2009 .

Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 2385 words.

Over the past 5 years we have seen an increase in the attention focused on the assessment of the potential health risk posed by nanoscale materials. The diversity of these materials with...

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A 28-Day Oral Dose Toxicity Study Enhanced to Detect Endocrine Effects of Hexabromocyclododecane in Wistar Rats

Leo T. M. van der Ven, Aart Verhoef, Ton van de Kuil, Wout Slob, Pim E. G. Leonards, Theo J. Visser, Timo Hamers, Maria Herlin, Helen Håkansson, Hanna Olausson, Aldert H. Piersma and Josephus G. Vos.

in Toxicological Sciences

December 2006; p ublished online September 2006 .

Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 8809 words.

A 28-day repeated dose study in rats (OECD407) enhanced for endocrine and immune parameters was performed with hexabromocyclododecane (HBCD). Rats were exposed by daily gavage to HBCD...

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A 2-Year Comparison Study of Crl:CD BR and Hsd:Sprague-Dawley SD Rats

JOHN C. PETTERSEN, ROBERT L. MORRISSEY, DONALD R. SAUNDERS, KENNETH L. PAVKOV, LOUIS G. LUEMPERT, JOHN C. TURNIER, DALE W. MATHESON and DANIEL R. SCHWARTZ.

in Toxicological Sciences

October 1996; p ublished online October 1996 .

Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 0 words.

In this 2-year study, the suitability of the Hsd:Sprague-Dawley SD (SD) as a replacement for the Crl:CD BR (CD) rat was assessed by comparing survival rates, palpable mass incidence, body...

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A 90-Day Chloroform Inhalation Study in F-344 Rats: Profile of Toxicity and Relevance to Cancer Studies

MICHAEL V. TEMPLIN, JEFFREY L. LARSON, BYRON E. BUTTERWORTH, KEITH C. JAMISON, JOEL R. LEININGER, STEPHANE MERY, KEVIN T. MORGAN, BRIAN A. WONG and DOUGLAS C. WOLF.

in Toxicological Sciences

July 1996; p ublished online July 1996 .

Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 0 words.

Composition of diet may influence growth, diseases, tumor rates, and responses to chemical treatment. Since 1980 the NIH–07 open formula nonpurified diet has been the selected diet for the...

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A 90-Day Chloroform Inhalation Study in Female and Male B6C3F<sub>1</sub> Mice: Implications for Cancer Risk Assessment

JEFFREY L. LARSON, MICHAEL V. TEMPLIN, DOUGLAS C. WOLF, KEITH C. JAMISON, JOEL R. LEINNINGER, STEPHANE MÈRY, KEVIN T. MORGAN, BRAIN A. WONG, RORY B. CONOLLY and BYRON E. BUTTERWORTH.

in Toxicological Sciences

March 1996; p ublished online March 1996 .

Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 0 words.

High doses of chloroform induced liver cancer in male and female B6C3F1 mice when administered by gavage, kidney cancer in male Osborne-Mendel rats when given by gavage or in the drinking...

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A 90-Day Drinking Water Toxicity Study in Rats of the Environmental Contaminant Ammonium Perchlorate

Joseph C. Siglin, David R. Mattie, Darol E. Dodd, Paul K. Hildebrandt and William H. Baker.

in Toxicological Sciences

September 2000; p ublished online September 2000 .

Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 9519 words.

Perchlorate (ClO 4), the dissociated anion of perchlorate salts such as ammonium, potassium, and sodium perchlorate, has been recently recognized as a persistent and pervasive...

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A 90-Day Toxicological Evaluation of Compound 1080 (Sodium Monofluoroacetate) in Sprague-Dawley Rats

Charles T. Eason and Patricia Turck.

in Toxicological Sciences

October 2002; p ublished online October 2002 .

Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 7262 words.

Groups of Sprague-Dawley rats received sodium monofluoroacetate (Compound 1080) at 0.025, 0.075, and 0.25 mg/kg by oral gavage once daily for 90 days and were then euthanized. The control...

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3.9 Å structure of the nucleosome core particle determined by phase-plate cryo-EM

Eugene Y.D. Chua, Vinod K. Vogirala, Oviya Inian, Andrew S.W. Wong, Lars Nordenskiöld, Juergen M. Plitzko, Radostin Danev and Sara Sandin.

in Nucleic Acids Research

September 2016; p ublished online August 2016 .

Journal Article. Subjects: Molecular and Cell Biology; Genetics and Genomics; Research Methods in Life Sciences; Proteins; Molecular Biology and Genetics. 3716 words.

The Volta phase plate is a recently developed electron cryo-microscopy (cryo-EM) device that enables contrast enhancement of biological samples. Here we have evaluated the potential of...

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A2 (<i>N</i>-Benzylpiperazine) a New Drug of Abuse in Sweden

Maria Wikström, Per Holmgren and Johan Ahlner.

in Journal of Analytical Toxicology

January 2004; p ublished online January 2004 .

Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 0 words.

N-Benzylpiperazine was tested in the beginning of the 1970s as a possible antidepressant drug. However, in both animal and human studies, it was shown to possess...

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ABA Regulates Subcellular Redistribution of OsABI-LIKE2, a Negative Regulator in ABA Signaling, to Control Root Architecture and Drought Resistance in <i>Oryza sativa</i>

Chengxiang Li, Hongyun Shen, Tao Wang and Xuelu Wang.

in Plant and Cell Physiology

December 2015; p ublished online October 2015 .

Journal Article. Subjects: Molecular Biology and Genetics; Biotechnology; Biochemistry; Bioinformatics and Computational Biology; Molecular and Cell Biology; Plant Sciences and Forestry; Plant Physiology. 8295 words.

The phytohormone ABA is a key stress signal in plants. Although the identification of ABA receptors led to significant progress in understanding the Arabidopsis ABA signaling pathway, there...

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