Oxford Index Browse

You are looking at 1-10 of 10,237 items for:

Science and Mathematics x Medical Toxicology x clear all

A 21st Century Paradigm for Evaluating the Health Hazards of Nanoscale Materials?

Nigel J. Walker and John R. Bucher.

in Toxicological Sciences

August 2009; p ublished online May 2009 .

Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 2385 words.

Over the past 5 years we have seen an increase in the attention focused on the assessment of the potential health risk posed by nanoscale materials. The diversity of these materials with...

Go to Oxford Journals »  home page

A 28-Day Oral Dose Toxicity Study Enhanced to Detect Endocrine Effects of Hexabromocyclododecane in Wistar Rats

Leo T. M. van der Ven, Aart Verhoef, Ton van de Kuil, Wout Slob, Pim E. G. Leonards, Theo J. Visser, Timo Hamers, Maria Herlin, Helen Håkansson, Hanna Olausson, Aldert H. Piersma and Josephus G. Vos.

in Toxicological Sciences

December 2006; p ublished online September 2006 .

Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 8809 words.

A 28-day repeated dose study in rats (OECD407) enhanced for endocrine and immune parameters was performed with hexabromocyclododecane (HBCD). Rats were exposed by daily gavage to HBCD...

Go to Oxford Journals »  home page

A 2-Year Comparison Study of Crl:CD BR and Hsd:Sprague-Dawley SD Rats

JOHN C. PETTERSEN, ROBERT L. MORRISSEY, DONALD R. SAUNDERS, KENNETH L. PAVKOV, LOUIS G. LUEMPERT, JOHN C. TURNIER, DALE W. MATHESON and DANIEL R. SCHWARTZ.

in Toxicological Sciences

October 1996; p ublished online October 1996 .

Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 0 words.

In this 2-year study, the suitability of the Hsd:Sprague-Dawley SD (SD) as a replacement for the Crl:CD BR (CD) rat was assessed by comparing survival rates, palpable mass incidence, body...

Go to Oxford Journals »  home page

A 90-Day Chloroform Inhalation Study in F-344 Rats: Profile of Toxicity and Relevance to Cancer Studies

MICHAEL V. TEMPLIN, JEFFREY L. LARSON, BYRON E. BUTTERWORTH, KEITH C. JAMISON, JOEL R. LEININGER, STEPHANE MERY, KEVIN T. MORGAN, BRIAN A. WONG and DOUGLAS C. WOLF.

in Toxicological Sciences

July 1996; p ublished online July 1996 .

Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 0 words.

Composition of diet may influence growth, diseases, tumor rates, and responses to chemical treatment. Since 1980 the NIH–07 open formula nonpurified diet has been the selected diet for the...

Go to Oxford Journals »  home page

A 90-Day Chloroform Inhalation Study in Female and Male B6C3F<sub>1</sub> Mice: Implications for Cancer Risk Assessment

JEFFREY L. LARSON, MICHAEL V. TEMPLIN, DOUGLAS C. WOLF, KEITH C. JAMISON, JOEL R. LEINNINGER, STEPHANE MÈRY, KEVIN T. MORGAN, BRAIN A. WONG, RORY B. CONOLLY and BYRON E. BUTTERWORTH.

in Toxicological Sciences

March 1996; p ublished online March 1996 .

Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 0 words.

High doses of chloroform induced liver cancer in male and female B6C3F1 mice when administered by gavage, kidney cancer in male Osborne-Mendel rats when given by gavage or in the drinking...

Go to Oxford Journals »  home page

A 90-Day Drinking Water Toxicity Study in Rats of the Environmental Contaminant Ammonium Perchlorate

Joseph C. Siglin, David R. Mattie, Darol E. Dodd, Paul K. Hildebrandt and William H. Baker.

in Toxicological Sciences

September 2000; p ublished online September 2000 .

Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 9519 words.

Perchlorate (ClO 4), the dissociated anion of perchlorate salts such as ammonium, potassium, and sodium perchlorate, has been recently recognized as a persistent and pervasive...

Go to Oxford Journals »  home page

A 90-Day Toxicological Evaluation of Compound 1080 (Sodium Monofluoroacetate) in Sprague-Dawley Rats

Charles T. Eason and Patricia Turck.

in Toxicological Sciences

October 2002; p ublished online October 2002 .

Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 7262 words.

Groups of Sprague-Dawley rats received sodium monofluoroacetate (Compound 1080) at 0.025, 0.075, and 0.25 mg/kg by oral gavage once daily for 90 days and were then euthanized. The control...

Go to Oxford Journals »  home page

A2 (<i>N</i>-Benzylpiperazine) a New Drug of Abuse in Sweden

Maria Wikström, Per Holmgren and Johan Ahlner.

in Journal of Analytical Toxicology

January 2004; p ublished online January 2004 .

Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 0 words.

N-Benzylpiperazine was tested in the beginning of the 1970s as a possible antidepressant drug. However, in both animal and human studies, it was shown to possess...

Go to Oxford Journals »  abstract

ABCB1 Protects Kidney Proximal Tubule Cells Against Cadmium-Induced Apoptosis: Roles of Cadmium and Ceramide Transport

Wing-Kee Lee, Blazej Torchalski, Naschla Kohistani and Frank Thévenod.

in Toxicological Sciences

June 2011; p ublished online March 2011 .

Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 6754 words.

Cadmium (Cd2+) damages the kidney proximal tubule (PT) by ceramide-dependent apoptosis and is also a class I carcinogen. Multidrug resistance P-glycoprotein (MDR1, ABCB1) confers resistance...

Go to Oxford Journals »  home page

Aberrant Adult Neurogenesis in the Subventricular Zone-Rostral Migratory Stream-Olfactory Bulb System Following Subchronic Manganese Exposure

Sherleen Fu, Wendy Jiang, Xiang Gao, Andrew Zeng, Daniel Cholger, Jason Cannon, Jinhui Chen and Wei Zheng.

in Toxicological Sciences

April 2016; p ublished online January 2016 .

Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 10873 words.

Adult neurogenesis occurs in brain subventricular zone (SVZ). Our recent data reveal an elevated proliferation of BrdU(+) cells in SVZ following subchronic manganese (Mn) exposure in rats....

Go to Oxford Journals »  home page