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Centre of epileptogenic tubers generate and propagate seizures in tuberous sclerosis

Lakshminarayanan Kannan, Simon Vogrin, Catherine Bailey, Wirginia Maixner and A. Simon Harvey.

in Brain

October 2016; p ublished online August 2016 .

Journal Article. Subjects: Neuropathology; Disorders of the Nervous System; Sleep Medicine. 9898 words.

See Duchowny (doi:10.1093/aww216) for a scientific commentary on this article.

Multiple seizure foci, seizure propagation and epileptic spasms complicate presurgical...

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Correlating magnetoencephalography to stereo-electroencephalography in patients undergoing epilepsy surgery

Hiroatsu Murakami, Zhong I. Wang, Ahmad Marashly, Balu Krishnan, Richard A. Prayson, Yosuke Kakisaka, John C. Mosher, Juan Bulacio, Jorge A. Gonzalez-Martinez, William E. Bingaman, Imad M. Najm, Richard C. Burgess and Andreas V. Alexopoulos.

in Brain

November 2016; p ublished online August 2016 .

Journal Article. Subjects: Neuropathology; Disorders of the Nervous System; Sleep Medicine. 7936 words.

See Bear and Kirsch (doi:10.1093/aww248) for a scientific commentary on this article.

Magnetoencephalography and stereo-electroencephalography are often necessary in...

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Cortisol fluctuations relate to interictal epileptiform discharges in stress sensitive epilepsy

Jolien S. van Campen, E. Lorraine Hompe, Floor E. Jansen, Demetrios N. Velis, Willem M. Otte, Fia van de Berg, Kees P. J. Braun, Gerhard H. Visser, Josemir W. Sander, Marian Joels and Maeike Zijlmans.

in Brain

June 2016; p ublished online March 2016 .

Journal Article. Subjects: Neuropathology; Disorders of the Nervous System; Sleep Medicine. 4093 words.

People with epilepsy often report seizures precipitated by stress. This is believed to be due to effects of stress hormones, such as cortisol, on neuronal excitability. Cortisol, regardless...

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Crowdsourcing reproducible seizure forecasting in human and canine epilepsy

Benjamin H. Brinkmann, Joost Wagenaar, Drew Abbot, Phillip Adkins, Simone C. Bosshard, Min Chen, Quang M. Tieng, Jialune He, F. J. Muñoz-Almaraz, Paloma Botella-Rocamora, Juan Pardo, Francisco Zamora-Martinez, Michael Hills, Wei Wu, Iryna Korshunova, Will Cukierski, Charles Vite, Edward E. Patterson, Brian Litt and Gregory A. Worrell.

in Brain

June 2016; p ublished online March 2016 .

Journal Article. Subjects: Neuropathology; Disorders of the Nervous System; Sleep Medicine. 6538 words.

See Mormann and Andrzejak (doi:10.1093/brain/aww091) for a scientific commentary on this article.  

Accurate forecasting of epileptic seizures has the...

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Epileptogenic effects of NMDAR antibodies in a passive transfer mouse model

Sukhvir Wright, Kevan Hashemi, Lukasz Stasiak, Julian Bartram, Bethan Lang, Angela Vincent and A. Louise Upton.

in Brain

November 2015; p ublished online September 2015 .

Journal Article. Subjects: Disorders of the Nervous System; Sleep Medicine; Neuropathology. 5511 words.

Most patients with N-methyl D-aspartate-receptor antibody encephalitis develop seizures but the epileptogenicity of the antibodies has not been investigated in vivo. Wireless...

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GABAergic inhibition shapes interictal dynamics in awake epileptic mice

Sarah Feldt Muldoon, Vincent Villette, Thomas Tressard, Arnaud Malvache, Susanne Reichinnek, Fabrice Bartolomei and Rosa Cossart.

in Brain

October 2015; p ublished online August 2015 .

Journal Article. Subjects: Disorders of the Nervous System; Sleep Medicine; Neuropathology. 10080 words.

Epilepsy is characterized by recurrent seizures and brief, synchronous bursts called interictal spikes that are present in-between seizures and observed as transient events in EEG signals....

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Global and regional functional connectivity maps of neural oscillations in focal epilepsy

Dario J. Englot, Leighton B. Hinkley, Naomi S. Kort, Brandon S. Imber, Danielle Mizuiri, Susanne M. Honma, Anne M. Findlay, Coleman Garrett, Paige L. Cheung, Mary Mantle, Phiroz E. Tarapore, Robert C. Knowlton, Edward F. Chang, Heidi E. Kirsch and Srikantan S. Nagarajan.

in Brain

August 2015; p ublished online May 2015 .

Journal Article. Subjects: Disorders of the Nervous System; Sleep Medicine; Neuropathology. 7859 words.

Intractable focal epilepsy is a devastating disorder with profound effects on cognition and quality of life. Epilepsy surgery can lead to seizure freedom in patients with focal epilepsy;...

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Hyperphosphorylated tau in patients with refractory epilepsy correlates with cognitive decline: a study of temporal lobe resections

Xin You Tai, Matthias Koepp, John S. Duncan, Nick Fox, Pamela Thompson, Sallie Baxendale, Joan Y. W. Liu, Cheryl Reeves, Zuzanna Michalak and Maria Thom.

in Brain

September 2016; p ublished online August 2016 .

Journal Article. Subjects: Neuropathology; Disorders of the Nervous System; Sleep Medicine. 8337 words.

See Bernasconi (doi:10.1093/aww202) for a scientific commentary on this article.

Temporal lobe epilepsy, the most prevalent form of chronic focal epilepsy, is...

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Interictal spikes and epileptic seizures: their relationship and underlying rhythmicity

Philippa J. Karoly, Dean R. Freestone, Ray Boston, David B. Grayden, David Himes, Kent Leyde, Udaya Seneviratne, Samuel Berkovic, Terence O’Brien and Mark J. Cook.

in Brain

April 2016; p ublished online February 2016 .

Journal Article. Subjects: Neuropathology; Disorders of the Nervous System; Sleep Medicine. 6859 words.

We report on a quantitative analysis of electrocorticography data from a study that acquired continuous ambulatory recordings in humans over extended periods of time. The objectives were to...

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Memory network plasticity after temporal lobe resection: a longitudinal functional imaging study

Meneka K. Sidhu, Jason Stretton, Gavin P. Winston, Andrew W. McEvoy, Mark Symms, Pamela J. Thompson, Matthias J. Koepp and John S. Duncan.

in Brain

February 2016; p ublished online January 2016 .

Journal Article. Subjects: Neuropathology; Disorders of the Nervous System; Sleep Medicine. 9240 words.

Anterior temporal lobe resection can control seizures in up to 80% of patients with temporal lobe epilepsy. Memory decrements are the main neurocognitive complication. Preoperative...

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