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Science and Mathematics x Disorders of the Nervous System x clear all

Abnormalities of fixation, saccade and pursuit in posterior cortical atrophy

Timothy J. Shakespeare, Diego Kaski, Keir X. X. Yong, Ross W. Paterson, Catherine F. Slattery, Natalie S. Ryan, Jonathan M. Schott and Sebastian J. Crutch.

in Brain

July 2015; p ublished online April 2015 .

Journal Article. Subjects: Neuropathology; Disorders of the Nervous System. 9780 words.

The clinico-neuroradiological syndrome posterior cortical atrophy is the cardinal ‘visual dementia’ and most common atypical Alzheimer’s disease phenotype, offering insights into mechanisms...

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Accumulation of murine amyloid-β mimics early Alzheimer’s disease

Markus Krohn, Alexander Bracke, Yosef Avchalumov, Toni Schumacher, Jacqueline Hofrichter, Kristin Paarmann, Christina Fröhlich, Cathleen Lange, Thomas Brüning, Oliver von Bohlen und Halbach and Jens Pahnke.

in Brain

August 2015; p ublished online May 2015 .

Journal Article. Subjects: Disorders of the Nervous System; Neuropathology. 7267 words.

Amyloidosis mouse models of Alzheimer’s disease are generally established by transgenic approaches leading to an overexpression of mutated human genes that are known to be involved in the...

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Adaptive Immunity

Jessica A. L. Hutter-Saunders, Larisa Y. Poluektova, Subhash Dhawan and Howard E. Gendelman.

in The Neurology of AIDS

December 2011; p ublished online September 2012 .

Chapter. Subjects: Disorders of the Nervous System; Infectious Diseases. 15588 words.

Innate and adaptive immune responses against human immunodeficiency virus type one (HIV-1) infection parallel those seen against misfolded, aggregated and nitrated proteins during...

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Addiction

R. Douglas Bruce.

in The Neurology of AIDS

December 2011; p ublished online September 2012 .

Chapter. Subjects: Disorders of the Nervous System; Infectious Diseases. 14126 words.

Substance use disorders can increase the risk of HIV infection directly, through the sharing of needles among injection drug users, and indirectly, through facilitation of high-risk sexual...

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Adjunctive Medicines

Harris A. Gelbard and Stuart A. Lipton.

in The Neurology of AIDS

December 2011; p ublished online September 2012 .

Chapter. Subjects: Disorders of the Nervous System; Infectious Diseases. 9875 words.

Antiretroviral drugs are the only therapy currently in general use for the treatment of HIV-associated neurocognitive disorders (HAND), but the treatment response to these agents may be...

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Adult Hippocampal Neurogenesis

Gerd Kempermann.

in Adult Neurogenesis 2

December 2010; p ublished online September 2012 .

Chapter. Subjects: Disorders of the Nervous System. 18661 words.

Adult neurogenesis in the adult hippocampus is partcularly interesting because of the role of the hippocampus in learning and memory. The new neurons are excitatory granule cells...

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Adult Neurogenesis 2

Gerd Kempermann, MD.

December 2010; p ublished online September 2012 .

Book. Subjects: Disorders of the Nervous System. 616 pages.

This resource is aimed at those interested in adult neurogenesis and stem cell biology of the adult brain, and covers the historical background and describes in detail adult neurogenesis in...

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Adult Neurogenesis in Different Animal Species

Gerd Kempermann.

in Adult Neurogenesis 2

December 2010; p ublished online September 2012 .

Chapter. Subjects: Disorders of the Nervous System. 20819 words.

This chapter describes adult neurogenesis in species other than rodents, including the particular challenges related to studying adult neurogenesis in humans. Many lower animals have very...

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Aging

Virawudh Soontornniyomkij and Cristian L. Achim.

in The Neurology of AIDS

December 2011; p ublished online September 2012 .

Chapter. Subjects: Disorders of the Nervous System; Infectious Diseases. 13168 words.

Dramatically improved survival due to HAART, and increases in newly diagnosed HIV infection in older adults, have lead to a growing number of older HIV+ patients. In the United States, it...

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Allogeneic haematopoietic stem cell transplantation for mitochondrial neurogastrointestinal encephalomyopathy

Joerg P. Halter, W. Michael, M. Schüpbach, Hanna Mandel, Carlo Casali, Kim Orchard, Matthew Collin, David Valcarcel, Attilio Rovelli, Massimiliano Filosto, Maria T. Dotti, Giuseppe Marotta, Guillem Pintos, Pere Barba, Anna Accarino, Christelle Ferra, Isabel Illa, Yves Beguin, Jaap A. Bakker, Jaap J. Boelens, Irenaeus F. M. de Coo, Keith Fay, Carolyn M. Sue, David Nachbaur, Heinz Zoller, Claudia Sobreira, Belinda Pinto Simoes, Simon R. Hammans, David Savage, Ramon Martí, Patrick F. Chinnery, Ronit Elhasid, Alois Gratwohl and Michio Hirano.

in Brain

October 2015; p ublished online August 2015 .

Journal Article. Subjects: Sensory and Motor Systems; Disorders of the Nervous System; Neuropathology. 6101 words.

Haematopoietic stem cell transplantation has been proposed as treatment for mitochondrial neurogastrointestinal encephalomyopathy, a rare fatal autosomal recessive disease due to TYMP mutat...

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