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Biological Sciences x Clinical Pharmacology and Therapeutics x clear all

Antibody Therapeutics

Journal. Subjects: Medicine and Health; Clinical Pharmacology and Therapeutics; Medicinal Chemistry; Proteins; Virology.

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Cardiac surgery-associated acute kidney injury: risk factors analysis and comparison of prediction models

Darko Kristovic, Ivica Horvatic, Ino Husedzinovic, Zeljko Sutlic, Igor Rudez, Davor Baric, Daniel Unic, Robert Blazekovic and Matija Crnogorac.

in Interactive CardioVascular and Thoracic Surgery

September 2015; p ublished online June 2015 .

Journal Article. Subjects: Research Methods in Life Sciences; Clinical Pharmacology and Therapeutics; Cardiovascular Medicine; Molecular and Cell Biology; Molecular Biology and Genetics. 5765 words.

OBJECTIVES

Cardiac surgery-associated acute kidney injury (AKI) is a well-known factor influencing patients' long-term morbidity and mortality. Several...

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Cardioplegic arrest induces apoptosis signal-pathway in myocardial endothelial cells and cardiac myocytes

Uwe M. Fischer, Oliver Klass, Ulrike Stock, Jerry Easo, Hans J. Geissler, Juergen H. Fischer, Wilhelm Bloch and Uwe Mehlhorn.

in European Journal of Cardio-Thoracic Surgery

June 2003; p ublished online June 2003 .

Journal Article. Subjects: Cardiothoracic Surgery; Clinical Pharmacology and Therapeutics; Cardiovascular Medicine; Molecular and Cell Biology; Molecular Biology and Genetics. 3332 words.

Objective: Myocardial ischemia–reperfusion is associated with free radical-mediated injury and may be involved in cardiac apoptosis. The purpose of our study was to investigate...

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Donor heart contractile dysfunction following prolonged ex vivo preservation can be prevented by gene-mediated β-adrenergic signaling modulation

Hendrik T. Tevaearai, G. Brant Walton, Andrea D. Eckhart, Janelle R. Keys and Walter J. Koch.

in European Journal of Cardio-Thoracic Surgery

November 2002; p ublished online November 2002 .

Journal Article. Subjects: Clinical Pharmacology and Therapeutics; Cardiovascular Medicine; Molecular and Cell Biology; Transplant Surgery; Molecular Biology and Genetics. 2991 words.

Objectives: Reperfusion after myocardial ischemia goes together with alteration of the β-adrenergic (βAR) signaling. Especially the level and catalytic activity of β AR kinase...

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Double giant coronary aneurysm: improved morphological study by computed tomography

Adrien Pasteur-Rousseau, Erik Bouvier, Patrick Donzeau-Gouge and Xavier Troussier.

in Interactive CardioVascular and Thoracic Surgery

October 2014; p ublished online July 2014 .

Journal Article. Subjects: Clinical Pharmacology and Therapeutics; Cardiovascular Medicine; Molecular Biology and Genetics; Molecular and Cell Biology. 1193 words.

Coronary artery aneurysm may cause coronary artery rupture, thromboembolism or haemodynamic problems related to compression. We report the case of a 68-year old man who was referred to an...

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Effect of PF-00547659 on Central Nervous System Immune Surveillance and Circulating β7+ T Cells in Crohn’s Disease: Report of the TOSCA Study

Geert D’Haens, Séverine Vermeire, Harald Vogelsang, Matthieu Allez, Pierre Desreumaux, Andre Van Gossum, William J Sandborn, Daniel C Baumgart, Richard M Ransohoff, Gail M Comer, Alaa Ahmad, Fabio Cataldi, John Cheng, Robert Clare, Kenneth J Gorelick, Annamarie Kaminski, Vivek Pradhan, Sunday Rivers, Matthew O Sikpi, Yanhua Zhang, Mina Hassan-Zahraee, Walter Reinisch and Olaf Stuve.

in Journal of Crohn's and Colitis

January 2018; p ublished online September 2017 .

Journal Article. Subjects: Clinical Pharmacology and Therapeutics; Gastroenterology; Pathology; Physiology; Research Methods in Life Sciences. 5592 words.

Abstract

Background and Aims

Progressive multifocal leukoencephalopathy [PML], a brain infection associated with...

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The effects of preoperative statins on the incidence of postoperative acute kidney injury in patients undergoing cardiac surgeries

Mohammad Hassan Nemati and Behrooz Astaneh.

in Interactive CardioVascular and Thoracic Surgery

October 2015; p ublished online July 2015 .

Journal Article. Subjects: Clinical Pharmacology and Therapeutics; Professional Development in Medicine; Molecular and Cell Biology; Cardiovascular Medicine; Cardiothoracic Surgery; Molecular Biology and Genetics. 3742 words.

OBJECTIVES

Recent evidence has emphasized multifunctional therapeutic effects of statins on renal protection after cardiac surgeries. We aimed to assess the...

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Effects of purified poloxamer 407 gel on vascular occlusion and the coronary endothelium

Munir Boodhwani, Jun Feng, Shigetoshi Mieno, Basel Ramlawi, Neel Sodha, Richard Clements and Frank W. Sellke.

in European Journal of Cardio-Thoracic Surgery

May 2006; p ublished online May 2006 .

Journal Article. Subjects: Cardiothoracic Surgery; Molecular and Cell Biology; Cardiovascular Medicine; Surgery; Clinical Pharmacology and Therapeutics; Molecular Biology and Genetics. 3889 words.

Objective: Vascular occlusion during off-pump coronary surgery often results in sub-optimal visualization and endothelial damage of the target vessel. We have previously...

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Enhancement of Na<sup>+</sup>,K<sup>+</sup>-ATPase and Ca<sup>2+</sup>-ATPase activities in multi-cycle ischemic preconditioning in rabbit hearts

Toshihiro Yorozuya, Naoto Adachi, Kentaro Dote, Kazuo Nakanishi, Yasushi Takasaki and Tatsuru Arai.

in European Journal of Cardio-Thoracic Surgery

November 2004; p ublished online November 2004 .

Journal Article. Subjects: Cardiothoracic Surgery; Molecular and Cell Biology; Cardiovascular Medicine; Clinical Pharmacology and Therapeutics; History of Medicine; Molecular Biology and Genetics. 3517 words.

Objective: Ischemic preconditioning (IP) has been shown to attenuate intracellular Na+ accumulation and Ca2+ overload during ischemia and reperfusion, both of which are closely...

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Fusion of bone marrow-derived stem cells with cardiomyocytes in a heterologous in vitro model

Jens Garbade, Andreas Schubert, Ardawan Julian Rastan, Dominik Lenz, Thomas Walther, Jan Fritz Gummert, Stefan Dhein and Friedrich-Wilhelm Mohr.

in European Journal of Cardio-Thoracic Surgery

November 2005; p ublished online November 2005 .

Journal Article. Subjects: Clinical Pharmacology and Therapeutics; Cardiovascular Medicine; Molecular and Cell Biology; Transplant Surgery; Molecular Biology and Genetics. 5250 words.

Objective: Recent studies have demonstrated that transplanted bone marrow-derived stem cells (BMCs) possess a broad differentiation potential and are able to form new...

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