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Biopsy-derived Intestinal Epithelial Cell Cultures for Pathway-based Stratification of Patients With Inflammatory Bowel Disease

Wiebe Vanhove, Kris Nys, Ingrid Arijs, Isabelle Cleynen, Manuel Noben, Sebastiaan De Schepper, Gert Van Assche, Marc Ferrante and Séverine Vermeire.

in Journal of Crohn's and Colitis

January 2018; p ublished online September 2017 .

Journal Article. Subjects: Pathology; Physiology; Research Methods in Life Sciences. 6507 words.

Abstract

Background

Endoplasmic reticulum [ER] stress was shown to be pivotal in the pathogenesis of inflammatory...

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CD16<sup>+</sup> Macrophages Mediate Fibrosis in Inflammatory Bowel Disease

Pedro Salvador, Dulce Carolina Macías-Ceja, Laura Gisbert-Ferrándiz, Carlos Hernández, David Bernardo, Rafael Alós, Francisco Navarro-Vicente, Juan Vicente Esplugues, Dolores Ortiz-Masiá, Maria Dolores Barrachina and Sara Calatayud.

in Journal of Crohn's and Colitis

April 2018; p ublished online January 2018 .

Journal Article. Subjects: Pathology; Physiology; Research Methods in Life Sciences. 5609 words.

Abstract

Background and Aims

Fibrosis is a common complication of Crohn’s disease [CD], and is related to...

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Effect of PF-00547659 on Central Nervous System Immune Surveillance and Circulating β7+ T Cells in Crohn’s Disease: Report of the TOSCA Study

Geert D’Haens, Séverine Vermeire, Harald Vogelsang, Matthieu Allez, Pierre Desreumaux, Andre Van Gossum, William J Sandborn, Daniel C Baumgart, Richard M Ransohoff, Gail M Comer, Alaa Ahmad, Fabio Cataldi, John Cheng, Robert Clare, Kenneth J Gorelick, Annamarie Kaminski, Vivek Pradhan, Sunday Rivers, Matthew O Sikpi, Yanhua Zhang, Mina Hassan-Zahraee, Walter Reinisch and Olaf Stuve.

in Journal of Crohn's and Colitis

January 2018; p ublished online September 2017 .

Journal Article. Subjects: Clinical Pharmacology and Therapeutics; Gastroenterology; Pathology; Physiology; Research Methods in Life Sciences. 5592 words.

Abstract

Background and Aims

Progressive multifocal leukoencephalopathy [PML], a brain infection associated with...

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Genomic and Expression Analyses Identify a Disease-Modifying Variant for Fibrostenotic Crohn’s Disease

Marijn C Visschedijk, Lieke M Spekhorst, Shih-Chin Cheng, Ellen S van Loo, B H Dianne Jansen, Tjasso Blokzijl, Hyunsuk Kil, Dirk J de Jong, Marieke Pierik, Jeroen P W J Maljaars, C Janneke van der Woude, Adriaan A van Bodegraven, Bas Oldenburg, Mark Löwenberg, Vincent B Nieuwenhuijs, Floris Imhann, Suzanne van Sommeren, Rudi Alberts, Ramnik J Xavier, Gerard Dijkstra, Klaas Nico Faber, C Marcelo Aldaz, Rinse K Weersma and Eleonora A M Festen.

in Journal of Crohn's and Colitis

April 2018; p ublished online January 2018 .

Journal Article. Subjects: Pathology; Physiology; Research Methods in Life Sciences; Clinical Genetics; Epidemiology. 4512 words.

Abstract

Background and Aims

Crohn’s disease [CD] is a chronic inflammatory disease with unpredictable behaviour....

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Halliburton, William Dobinson (1860–1931), physiologist and biochemist

R. J. S. McDowall.

in Oxford Dictionary of National Biography

September 2004; p ublished online September 2004 .

Reference Entry. Subjects: Physiology; Biochemistry. 949 words.

Halliburton, William Dobinson (1860–1931), physiologist and biochemist, was born in London on 21 June 1860, the only son of Thomas Halliburton, a Yorkshireman, of Upper Norwood, and his...

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Henderson, Lawrence Joseph

John Parascandola.

in American National Biography Online

January 1999; p ublished online February 2000 .

Reference Entry. Subjects: Physiology; Biochemistry. 1379 words.

Henderson, Lawrence Joseph (03 June 1878–10 February 1942), biochemist and physiologist, was born in Lynn, Massachusetts, the son of Joseph Henderson, a businessman, and Mary Bosworth....

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Keatinge, William Richard [Bill] (1931–2008), physiologist

Margaret M. Bird.

in Oxford Dictionary of National Biography

March 2013; p ublished online January 2012 .

Reference Entry. Subjects: Physiology; Veterinary Medicine. 1038 words.

Keatinge, William Richard [Bill] (1931–2008), physiologist, was born on 18 May 1931 at 30 Beaufort Mansions, Chelsea, London, the only son of Sir Edgar Mayne Keatinge (1905–1998), land...

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Lusk, Graham

David Y. Cooper.

in American National Biography Online

January 1999; p ublished online February 2000 .

Reference Entry. Subjects: Physiology; Biochemistry. 1051 words.

Lusk, Graham (15 February 1866–18 July 1932), physiologist and biochemist, was born in Bridgeport, Connecticut, the son of William Thompson Lusk, an obstetrician, and Mary Hartwell...

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Macleod, John James Rickard (1876–1935), physiologist and biochemist

W. J. Bishop.

in Oxford Dictionary of National Biography

September 2004; p ublished online September 2004 .

Reference Entry. Subjects: Physiology; Biochemistry. 1099 words.

Macleod, John James Rickard (1876–1935), physiologist and biochemist, was born at the Free Church manse, New Clunie, near Dunkeld, Perthshire, on 6 September 1876, the son of Robert Macleod...

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Oral Delivery of Nanoparticles Loaded With Ginger Active Compound, 6-Shogaol, Attenuates Ulcerative Colitis and Promotes Wound Healing in a Murine Model of Ulcerative Colitis

Mingzhen Zhang, Changlong Xu, Dandan Liu, Moon Kwon Han, Lixin Wang and Didier Merlin.

in Journal of Crohn's and Colitis

January 2018; p ublished online August 2017 .

Journal Article. Subjects: Pathology; Physiology; Research Methods in Life Sciences. 7784 words.

Abstract

Background and Aims

Oral drug delivery is the most attractive pathway for ulcerative colitis [UC] therapy,...

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