Adiponectin suppression of late inflammatory mediator, HMGB1-induced cytokine expression in RAW264 macrophage cells
in The Journal of Biochemistry
February 2018; p ublished online October 2017 .
Journal Article. Subjects: Cell Biology; Biotechnology; Biochemistry; Molecular and Cell Biology. 5939 words.
Abstract
High-mobility group protein B1 (HMGB1) is a late inflammatory mediator released from inflammatory cells when stimulated, resulting in exaggerating...
Amino acid sequence analysis and characterization of a ribonuclease from starfish Asterias amurensis
in The Journal of Biochemistry
September 2016; p ublished online February 2016 .
Journal Article. Subjects: Cell Biology; Biotechnology; Biochemistry; Molecular and Cell Biology. 5114 words.
The aim of this study was to phylogenetically characterize the location of the RNase T2 enzyme in the starfish (Asterias amurensis). We isolated an RNase T2 ribonuclease (RNase Aa) from the...
5-Aminoimidazole-4-carboxyamide-1-β-D-ribofranoside stimulates the rat enhancer of split- and hairy-related protein-2 gene via atypical protein kinase C lambda
in The Journal of Biochemistry
April 2016; p ublished online November 2015 .
Journal Article. Subjects: Cell Biology; Biotechnology; Biochemistry; Molecular and Cell Biology. 4678 words.
The 5′-AMP-activated protein kinase (AMPK) functions as a cellular energy sensor. 5-Aminoimidazole-4-carboxyamide-1-β-D-ribofranoside (AICAR) is a chemical activator of AMPK. In the liver,...
Analysis of novel Sir3 binding regions in Saccharomyces cerevisiae
in The Journal of Biochemistry
July 2016; p ublished online March 2016 .
Journal Article. Subjects: Cell Biology; Biotechnology; Biochemistry; Molecular and Cell Biology. 3629 words.
In Saccharomyces cerevisiae, the HMR, HML, telomere and rDNA regions are silenced. Silencing at the rDNA region requires Sir2, and silencing at the HMR, HML and telomere regions requires...
Antioxidants as stabilizers for His6-OPH: is this an unusual or regular role for them with enzymes?
in The Journal of Biochemistry
November 2017; p ublished online June 2017 .
Journal Article. Subjects: Cell Biology; Biotechnology; Biochemistry; Molecular and Cell Biology. 4542 words.
Abstract
The effect of 14 different antioxidants on the activity of a hexahistidine-tagged organophosphorus hydrolase (His6-OPH) has been studied in vitro. It...
Apical secretion of Wnt1 in polarized epithelial cells is regulated by exocyst-mediated trafficking
in The Journal of Biochemistry
November 2017; p ublished online July 2017 .
Journal Article. Subjects: Cell Biology; Biotechnology; Biochemistry; Molecular and Cell Biology. 6343 words.
Abstract
Wnts are glycosylated proteins secreted from various cell types including mesenchymal, hematopoietic and epithelial cells. Directional secretion of...
Aptamers that bind specifically to human KPNA2 (importin-α1) and efficiently interfere with nuclear transport
in The Journal of Biochemistry
November 2016; p ublished online May 2016 .
Journal Article. Subjects: Cell Biology; Biotechnology; Biochemistry; Molecular and Cell Biology. 5948 words.
The importin-α family of proteins plays an important role in the eukaryotic importin/exportin nuclear transport system. These proteins recognize a nuclear localization signal (NLS) within...
Aureobasidium pullulans-cultured fluid induces IL-18 production, leading to Th1-polarization during influenza A virus infection
in The Journal of Biochemistry
January 2018; p ublished online October 2017 .
Journal Article. Subjects: Cell Biology; Biotechnology; Biochemistry; Molecular and Cell Biology. 4309 words.
Abstract
Several microbial molecules with pathogen-associated molecular patterns stimulate host innate immune responses. The innate immune system plays a...
Azide anions inhibit GH-18 endochitinase and GH-20 Exo β-N-acetylglucosaminidase from the marine bacterium Vibrio harveyi
in The Journal of Biochemistry
February 2016; p ublished online September 2015 .
Journal Article. Subjects: Cell Biology; Biotechnology; Biochemistry; Molecular and Cell Biology. 6269 words.
Vibrio harveyi is a bioluminescent marine bacterium that utilizes chitin as its sole source of energy. In the course of chitin degradation, the bacterium primarily secretes an...
Basigin (CD147), a multifunctional transmembrane glycoprotein with various binding partners
in The Journal of Biochemistry
May 2016; p ublished online December 2015 .
Journal Article. Subjects: Cell Biology; Biotechnology; Biochemistry; Molecular and Cell Biology. 6019 words.
Basigin, also called CD147 or EMMPRIN, is a transmembrane glycoprotein that belongs to the immunoglobulin superfamily. Basigin has isoforms; the common form (basigin or basigin-2) has two...