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Biological Sciences x Developmental Biology x clear all

Adolescent epigenetic profiles and environmental exposures from early life through peri-adolescence

Jaclyn M. Goodrich, Dana C. Dolinoy, Brisa N. Sánchez, Zhenzhen Zhang, John D. Meeker, Adriana Mercado-Garcia, Maritsa Solano-González, Howard Hu, Martha M. Téllez-Rojo and Karen E. Peterson.

in Environmental Epigenetics

P ublished online August 2016 .

Journal Article. Subjects: Molecular Biology and Genetics; Biological Sciences; Developmental Biology; Evolutionary Biology; Genetics and Genomics. 7573 words.

Epigenetic perturbations induced by environmental exposures at susceptible lifestages contribute to disease development. Even so, the influence of early life and ongoing exposures on the...

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Alterations in sperm DNA methylation, non-coding RNA expression, and histone retention mediate vinclozolin-induced epigenetic transgenerational inheritance of disease

Millissia Ben Maamar, Ingrid Sadler-Riggleman, Daniel Beck, Margaux McBirney, Eric Nilsson, Rachel Klukovich, Yeming Xie, Chong Tang, Wei Yan and Michael K Skinner.

Edited by Christopher Faulk.

in Environmental Epigenetics

P ublished online April 2018 .

Journal Article. Subjects: Molecular Biology and Genetics; Biological Sciences; Developmental Biology; Evolutionary Biology; Genetics and Genomics. 10498 words.

Abstract

Epigenetic transgenerational inheritance of disease and phenotypic variation can be induced by several toxicants, such as vinclozolin. This phenomenon...

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Ancestral vinclozolin exposure alters the epigenetic transgenerational inheritance of sperm small noncoding RNAs

Andrew Schuster, Michael K. Skinner and Wei Yan.

in Environmental Epigenetics

P ublished online March 2016 .

Journal Article. Subjects: Molecular Biology and Genetics; Biological Sciences; Developmental Biology; Evolutionary Biology; Genetics and Genomics. 6687 words.

Exposure to the agricultural fungicide vinclozolin during gestation promotes a higher incidence of various diseases in the subsequent unexposed F3 and F4 generations. This phenomenon is...

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Animal development in a microbial world

Spencer V. Nyholm and Margaret J. McFall-Ngai.

in Towards a Theory of Development

May 2014; p ublished online August 2014 .

Chapter. Subjects: Developmental Biology. 9148 words.

Advances in molecular biology over the last decade have enabled researchers to identify and characterize microbial partners that live in association with animals. These data have indicated...

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Biology of Reproduction

Journal. Subjects: Reproduction, Growth and Development; Reproductive Medicine; Developmental Biology; Animal Reproduction.

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Bisphenol-A and metabolic diseases: epigenetic, developmental and transgenerational basis

Paloma Alonso-Magdalena, Francisco J. Rivera and Carlos Guerrero-Bosagna.

in Environmental Epigenetics

P ublished online October 2016 .

Journal Article. Subjects: Molecular Biology and Genetics; Biological Sciences; Developmental Biology; Evolutionary Biology; Genetics and Genomics. 6177 words.

Exposure to environmental toxicants is now accepted as a factor contributing to the increasing incidence of obesity and metabolic diseases around the world. Such environmental compounds are...

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Bugs in the program: can pregnancy drugs and smoking disturb molecular reprogramming of the fetal germline, increasing heritable risk for autism and neurodevelopmental disorders?

Jill Escher.

in Environmental Epigenetics

P ublished online April 2018 .

Journal Article. Subjects: Molecular Biology and Genetics; Biological Sciences; Developmental Biology; Evolutionary Biology; Genetics and Genomics. 4239 words.

Abstract

In a seeming paradox, the prevalence of autism spectrum disorder (ASD) has surged, while at the same time research has pointed to the strong...

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Cell differentiation and stem cells

Lewis Wolpert.

in Developmental Biology: A Very Short Introduction

August 2011; p ublished online September 2013 .

Chapter. Subjects: Developmental Biology. 3554 words.

The development of many different cell types such as muscle, blood, and skin is known as cell differentiation. ‘Cell differentiation and stem cells’ shows how this first occurs in the...

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Cell differentiation is a stochastic process subjected to natural selection

Jean-Jacques Kupiec.

in Towards a Theory of Development

May 2014; p ublished online August 2014 .

Chapter. Subjects: Developmental Biology. 12462 words.

In contrast to classical determinist theories of development, an accumulation of data obtained over the last 30 years shows that gene expression is a stochastic phenomenon. Since gene...

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Cells

in Developmental Biology

August 2011; p ublished online September 2013 .

Chapter. Subjects: Developmental Biology. 1848 words.

Development results from the coordinated behaviour of cells and is almost entirely determined by which proteins the cell contains. ‘Cells’ discusses the major processes involved in...

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