A 10-year follow-up of hippocampal volume on magnetic resonance imaging in early dementia and cognitive decline
April 2010; published online April 2010.
Journal Article. Subjects: neurology; neuroscience. 6256 words.
Hippocampal atrophy is frequently observed on magnetic resonance images from patients with Alzheimer’s disease and persons with mild cognitive impairment. Even in asymptomatic elderly, a small...
A 1H-MR Spectroscopy Study of Changes in Glutamate and Glutamine (Glx) Concentrations in Frontal Spectra after Administration of Memantine
in Cerebral Cortex
April 2010; published online July 2009.
Journal Article. Subjects: neuroscience. 4949 words.
Glutamate is the major excitatory neurotransmitter in the brain and therefore important for cognitive functions. The aim of the study was to investigate if administration of the N-methyl-D-aspartate...
April 2007; published online April 2007.
Journal Article. Subjects: neurology; neuroscience. 1153 words.
The A9 dopamine neuron component in grafts of ventral mesencephalon is an important determinant for recovery of motor function in a rat model of Parkinson’s disease
February 2010; published online January 2010.
Journal Article. Subjects: neurology; neuroscience. 8383 words.
Grafts of foetal ventral mesencephalon, used in cell replacement therapy for Parkinson’s disease, are known to contain a mix of dopamine neuronal subtypes including the A9 neurons of the substantia...
October 2008; published online September 2008.
Journal Article. Subjects: neurology; neuroscience. 5929 words.
By preventing access of drugs to the CNS, the blood–brain barrier hampers developments in brain pharmacotherapy. Strong efforts are currently being made to identify drugs that accumulate more...
ABC-transporter gene-polymorphisms are potential pharmacogenetic markers for mitoxantrone response in multiple sclerosis
September 2009; published online July 2009.
Journal Article. Subjects: neurology; neuroscience. 7541 words.
Escalation therapy with mitoxantrone (MX) in highly active multiple sclerosis is limited by partially dose-dependent side-effects. Predictors of therapeutic response may result in individualized...
in From Development to Degeneration and Regeneration of the Nervous System
December 2008; published online May 2009.
Chapter. Subjects: neuroscience. 7905 words.
This chapter discusses studies on the properties of abnormal cells and synaptic circuits in pediatric cortical dysplasia (CD). It provides a working hypothesis concerning how CD tissue may be able to...
September 2000; published online September 2000.
Journal Article. Subjects: neurology; neuroscience. 5493 words.
Trafficking of inflammatory T cells into the central nervous system (CNS) plays an important role in the pathogenesis of multiple sclerosis. The directional migratory ability of peripheral T...
in Archives of Clinical Neuropsychology
January 1997; published online January 1997.
Journal Article. Subjects: neuroscience; neuropsychology. 0 words.