protease nexin-1

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A serine protease inhibitor (PN-1, plasminogen activator inhibitor type 1 member 2, glial derived neurite promoting factor, glia-derived nexin, GDN, serpin E2, 397 aa), that is an important physiological regulator of α-thrombin in tissues and also inhibits plasmin and plasminogen activators. It is neuroprotective in a number of assay systems and is highly expressed and developmentally regulated in the nervous system.

Subjects: Medicine and Health.

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