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hepatocyte growth factor

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cytokine

Overview page. Subjects: Medicine and Health — Science and Mathematics.

pl. n. protein molecules, released by cells when activated by antigen, that are involved in cell-to-cell communications, acting as enhancing mediators for immune responses...

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growth factor

Overview page. Subjects: Medicine and Health.

(grohth)

a polypeptide that is produced by cells and stimulates them to proliferate. Some are involved in the abnormal regulation of growth seen in cancer.

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hepatocyte growth factor receptor

Overview page. Subjects: Chemistry.

A type I membrane protein that binds hepatocyte growth factor and mediates its intracellular action by a protein tyrosine kinase (EC 2.7.1.112) activity on its intracellular domain. It is...

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Kunitz domain

Overview page. Subjects: Medicine and Health.

Protein domain characteristic of inhibitors of the S1 serine peptidase family. Examples are aprotinin, trypstatin, a rat mast cell inhibitor of trypsin, and tissue factor pathway inhibitor...

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met

Overview page. Subjects: Chemistry — Medicine and Health.

An oncogene from a chemically transformed human osteosarcoma-derived cell line. The alpha subunit of the c-Met proto-oncogene product is extracellular, the beta subunit is the hepatocyte...

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scatter factor

Overview page. Subjects: Medicine and Health.

A motility factor (motogen) that stimulates dispersal (scattering) of colonies of epithelial and endothelial cells as single cells. It is identical to hepatocyte growth factor, but is not...

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sea oncogene

Overview page. Subjects: Medicine and Health.

An oncogene (S13 avian erythroblastosis oncogene homologue) that encodes a receptor tyrosine kinase of the Met/*hepatocyte growth factor/scatter factor family.

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