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hypersensitivity

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allergen

Overview page. Subjects: Medicine and Health.

A substance that will cause an allergic response (see allergy). Usually applied to substances such as pollens or insect venoms that cause immediate-type hypersensitivity reactions.

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allergy

Overview page. Subjects: Medicine and Health.

A hypersensitivity response to an antigen (allergen) to which a primary immune response has already been made. In extreme cases there may be anaphylaxis.

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anaphylaxis

Overview page. Subjects: Medicine and Health.

Extreme sensitivity to an allergen, clinically manifest as acute-onset swelling of mucosal tissues including the trachea, where it causes life-threatening obstruction of the airway.

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antigen-antibody complex

Overview page. Subjects: Medicine and Health — Chemistry.

The product of the interaction between antigen and immunoglobulin. A polyvalent antigen can bind to more than one antibody and the immune complex tends to be large and insoluble and may...

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Arthus reaction

Overview page. Subjects: Chemistry.

A localized haemorrhagic inflammation that occurs if antigen is experimentally injected into an animal with a high level of circulating antibody against that antigen. A similar reaction may...

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atopy

Overview page. Subjects: Medicine and Health.

n. a form of allergy in which there is a hereditary or constitutional tendency to develop hypersensitivity reactions (e.g. hay fever, allergic asthma, atopic eczema) in...

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bagassosis

Overview page. Subjects: Medicine and Health.

n. a form of external allergic alveolitis caused by exposure to the dust of mouldy bagasse, the residue of sugar cane after the sugar has been extracted, which is used in the...

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cell-mediated immunity

Overview page. Subjects: Chemistry — Medicine and Health.

An immune response involving effector T cells rather than the production of humoral antibody. Cell-mediated responses are involved in allograft rejection, delayed hypersensitivity, and...

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chitinase

Overview page. Subjects: Biological Sciences — Chemistry.

An enzyme that catalyses the hydrolysis of chitin, a major constituent of fungal cell walls and of the exoskeleton of insects and other arthropods. It is synthesized by certain...

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contact hypersensitivity

Overview page. Subjects: Chemistry.

A form of immunological hypersensitivity, immediate or delayed, that is provoked in the skin or mucous surfaces by contact with specific agents acting as either antigens or haptens.

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