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megakaryocyte

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giant cell

Overview page. Subjects: Medicine and Health.

Any large cell, such as a megakaryocyte. Giant cells may have one or many nuclei.

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megakaryoblast

Overview page. Subjects: Medicine and Health.

n. a cell that gives rise to the platelet-forming cell megakaryocyte, found in the blood-forming tissue of the bone marrow. It is derived from a haemopoietic stem cell and...

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myeloid cells

Overview page. Subjects: Medicine and Health.

One of the two main classes of cells produced by the bone marrow, the others being lymphoid cells. The myeloid series includes megakaryocytes, erythrocyte precursors, mononuclear...

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promegakaryocyte

Overview page. Subjects: Medicine and Health.

n. an immature cell, found in the bone marrow, that develops into a megakaryocyte.

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thrombocythaemia

Overview page. Subjects: Medicine and Health.

(throm-boh-si-th'ee-miă)

a disease in which there is an abnormal proliferation of megakaryocytes, leading to an increased number of platelets in the blood.

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thrombopoiesis

Overview page. Subjects: Medicine and Health.

n. the process of blood platelet production. Platelets are formed as fragments of cytoplasm shed from giant cells (megakaryocytes) in the bone marrow by a budding process.

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thrombopoietin

Overview page. Subjects: Medicine and Health.

A growth factor (TPO, thrombopoiesis stimulating factor, TSF, 353 aa) that regulates the proliferation of megakaryocytes and platelet production (thrombopoiesis). Mutation causes essential...

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