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nucleosome

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chromatin

Overview page. Subjects: Biological Sciences — Chemistry.

The complex of nucleic acids (DNA and RNA) and proteins (histones and nonhistones) comprising eukaryotic chromosomes. See Chronology, 1879, Flemming; 1976, Finch and Klug.

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chromatosome

Overview page. Subjects: Genetics and Genomics.

A DNA protein complex consisting of a nucleosome (q.v.), the linker DNA segment, and its H1 histone. See histones, nucleosome.

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chromosome condensation

Overview page. Subjects: Genetics and Genomics.

The process whereby eukaryotic chromosomes become shorter and thicker during prophase as a consequence of coiling and supercoiling of chromatic strands. See Chronology, 1970, Johnson and...

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condensed

Overview page. Subjects: Chemistry.

1 converted to a dense or denser form; e.g. condensed DNA in nucleosomes or in the early stages of maturation of T‐even phages; or the condensed form of mitochondria in ...

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core particle

Overview page. Subjects: Chemistry.

A structural unit of eukaryotic chromosomes revealed by digestion with micrococcal nuclease to consist of a histone octamer and a 146 base pair segment of DNA. See nucleosome.

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histone

Overview page. Subjects: Biological Sciences.

One of a group of basic, globular, simple proteins that have a high content of the amino acids arginine and lysine. Histones form part of the chromosomal material of eukaryotic cells and...

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laddering

Overview page. Subjects: Medicine and Health.

The regular pattern of oligonucleotides on a gel that is characteristic of apoptotic cells, a result of the cleavage of the DNA strand between nucleosome beads by endonucleases.

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nu body

Overview page. Subjects: Chemistry.

or

or

a type of spheroid particle seen on electron‐microscopic examination of chromatin; now thought to be the same as a...

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nucleodisome

Overview page. Subjects: Chemistry.

A structure consisting of two nucleosomes and isolable under certain conditions from some forms of chromatin.

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octamer

Overview page. Subjects: Chemistry — Medicine and Health.

1. The complex of eight histone proteins, two each of H2A, H2B, H3, and H4, that forms the core of the nucleosome.

2. The eight-base motif common in...

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