Oxford Index Search Results

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��-sarcin x clear all

Pokeweed antiviral protein cleaves double-stranded supercoiled DNA using the same active site required to depurinate rRNA

Pinger Wang and Nilgun E. Tumer.

in Nucleic Acids Research

April 1999; p ublished online April 1999 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 4761 words.

Ribosome-inactivating proteins (RIPs) are N-glycosylases that remove a specific adenine from the sarcin/ricin loop of the large rRNA in a manner analogous to N-glycosylases that are...

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Computational identification of RNA functional determinants by three-dimensional quantitative structure–activity relationships

Marc-Frédérick Blanchet, Karine St-Onge, Véronique Lisi, Julie Robitaille, Sylvie Hamel and François Major.

in Nucleic Acids Research

September 2014; p ublished online September 2014 .

Journal Article. Subjects: Molecular and Cell Biology; Bioinformatics and Computational Biology. 6069 words.

Anti-infection drugs target vital functions of infectious agents, including their ribosome and other essential non-coding RNAs. One of the reasons infectious agents become resistant to...

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Chemical probing of RNA with the hydroxyl radical at single-atom resolution

Shakti Ingle, Robert N. Azad, Swapan S. Jain and Thomas D. Tullius.

in Nucleic Acids Research

November 2014; p ublished online October 2014 .

Journal Article. Subjects: Molecular and Cell Biology. 7522 words.

While hydroxyl radical cleavage is widely used to map RNA tertiary structure, lack of mechanistic understanding of strand break formation limits the degree of structural insight that can be...

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A switch-on mechanism to activate maize ribosome-inactivating protein for targeting HIV-infected cells

Sue Ka-Yee Law, Rui-Rui Wang, Amanda Nga-Sze Mak, Kam-Bo Wong, Yong-Tang Zheng and Pang-Chui Shaw.

in Nucleic Acids Research

October 2010; p ublished online June 2010 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 5868 words.

Maize ribosome-inactivating protein (RIP) is a plant toxin that inactivates eukaryotic ribosomes by depurinating a specific adenine residue at the α-sarcin/ricin loop of 28S rRNA. Maize RIP...

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RNAMotifScan: automatic identification of RNA structural motifs using secondary structural alignment

Cuncong Zhong, Haixu Tang and Shaojie Zhang.

in Nucleic Acids Research

October 2010; p ublished online August 2010 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 6646 words.

Recent studies have shown that RNA structural motifs play essential roles in RNA folding and interaction with other molecules. Computational identification and analysis of RNA structural...

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WebFR3D—a server for finding, aligning and analyzing recurrent RNA 3D motifs

Anton I. Petrov, Craig L. Zirbel and Neocles B. Leontis.

in Nucleic Acids Research

July 2011; p ublished online April 2011 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 2863 words.

WebFR3D is the on-line version of ‘Find RNA 3D’ (FR3D), a program for annotating atomic-resolution RNA 3D structure files and searching them efficiently to locate and compare RNA 3D...

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Functional interaction between bases C1049 in domain II and G2751 in domain VI of 23S rRNA in <i>Escherichia coli</i> ribosomes

Tomohiro Miyoshi and Toshio Uchiumi.

in Nucleic Acids Research

April 2008; p ublished online February 2008 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 5522 words.

The factor-binding center within the Escherichia coli ribosome is comprised of two discrete domains of 23S rRNA: the GTPase-associated region (GAR) in domain II and the sarcin–ricin loop in...

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Interaction between trichosanthin, a ribosome-inactivating protein, and the ribosomal stalk protein P2 by chemical shift perturbation and mutagenesis analyses

Denise S.B. Chan, Lai-On Chu, Ka-Ming Lee, Priscilla H.M. Too, Kit-Wan Ma, Kong-Hung Sze, Guang Zhu, Pang-Chui Shaw and Kam-Bo Wong.

in Nucleic Acids Research

March 2007; p ublished online February 2007 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 7254 words.

Trichosanthin (TCS) is a type I ribosome-inactivating protein that inactivates ribosome by enzymatically depurinating the A4324 at the α-sarcin/ricin loop of 28S rRNA. We have shown in this...

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The common and the distinctive features of the bulged‐G motif based on a 1.04 Å resolution RNA structure

Carl C. Correll, Jutta Beneken, Matthew J. Plantinga, Melissa Lubbers and Yuen‐Ling Chan.

in Nucleic Acids Research

December 2003; p ublished online December 2003 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 10172 words.

Bulged‐G motifs are ubiquitous internal RNA loops that provide specific recognition sites for proteins and RNAs. To establish the common and distinctive features of the motif we determined...

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Identification of additional rRNA fragments encoded by the <i>Plasmodium falciparum</i> 6 kb element

Jean E. Feagin, Barbara L. Mericle, Erica Werner and Mark Morris.

in Nucleic Acids Research

January 1997; p ublished online January 1997 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 5584 words.

Sequences similar to mitochondrial large and small subunit rRNAs are found as small scattered fragments on a tandemly reiterated 6 kb element in the human malaria parasite Plasmodium...

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