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Overview page. Subjects: Chemistry — Medicine and Health.

n. a lipoprotein particle present in the blood after digested fat has been absorbed from the small intestine. The lipid portion consists largely of triglycerides, which are...

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Use of Model-Based Compartmental Analysis to Study Effects of 2,3,7,8-Tetrachlorodibenzo-<i>p</i>-dioxin on Vitamin A Kinetics in Rats

Sean K. Kelley, Charlotte B. Nilsson, Michael H. Green, Joanne Balrner Green and Helen Håkansson.

in Toxicological Sciences

July 1998; p ublished online July 1998 .

Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 0 words.

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a highly toxic, widespread environmental contaminant that has dramatic adverse effects on the metabolism of vitamin A. We used model-based...

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Physiological Modeling Reveals Novel Pharmacokinetic Behavior for Inhaled Octamethylcyclotetrasiloxane in Rats

Melvin E. Andersen, Ramesh Sarangapani, Richard H. Reitz, Robert H. Gallavan, Ivan D. Dobrev and Kathleen P. Plotzke.

in Toxicological Sciences

April 2001; p ublished online April 2001 .

Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 10225 words.

Octamethylcyclotetrasiloxane (D4) is an ingredient in selected consumer and precision cleaning products. Workplace inhalation exposures may occur in some D4 production operations. In this...

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