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1,1-dimethylhydrazine

Overview page. Subjects: Public Health and Epidemiology.

A substance used as rocket fuel, in the manufacture of antioxidant rubber compounds, in pesticides, and for other purposes. It is a possible human carcinogen. Exposure can cause liver...

See overview in Oxford Index

1,1-dimethylhydrazine

Overview page. Subjects: Public Health and Epidemiology.

A substance used as rocket fuel, in the manufacture of antioxidant rubber compounds, in pesticides, and for other purposes. It is a possible human carcinogen. Exposure can cause liver...

See overview in Oxford Index

1,1-dimethylhydrazine

Edited by John M. Last.

in A Dictionary of Public Health

January 2007; p ublished online January 2007 .

Reference Entry. Subjects: Public Health and Epidemiology. 39 words.

A substance used as rocket fuel, in the manufacture of antioxidant rubber compounds, in pesticides, and for other purposes. It

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Chemopreventive effects of carotenoids and curcumins on mouse colon carcinogenesis after 1,2-dimethylhydrazine initiation.

J M Kim, S Araki, D J Kim, C B Park, N Takasuka, H Baba-Toriyama, T Ota, Z Nir, F Khachik, N Shimidzu, Y Tanaka, T Osawa, T Uraji, M Murakoshi, H Nishino and H Tsuda.

in Carcinogenesis

January 1998; p ublished online January 1998 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 0 words.

The present study was carried out to examine the chemopreventive effects of carotenoids such as fucoxanthin, lycopene and lutein as well as curcumin and its derivative, tetrahydrocurcumin...

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1,2-Dimethylhydrazine-Induced Colon Carcinoma and Lymphoma in msh2<sup>−/−</sup> Mice

Claudia Colussi, Silvia Fiumicino, Alessandro Giuliani, Sandra Rosini, Piero Musiani, Caterina Macrí, Christopher S. Potten, Marco Crescenzi and Margherita Bignami.

in JNCI: Journal of the National Cancer Institute

October 2001; p ublished online October 2001 .

Journal Article. Subjects: Medical Oncology. 5792 words.

Background: Defective mismatch repair (MMR) in humans is particularly associated with familial colorectal cancer, but defective repair in mice is generally associated with...

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Analysis of Cigarette Mainstream Smoke for 1,1-Dimethylhydrazine and Vinyl Acetate by Gas Chromatography-Mass Spectrometry

J. Diekmann, C. Biefel and K. Rustemeier.

in Journal of Chromatographic Science

October 2002; p ublished online October 2002 .

Journal Article. Subjects: Chemistry. 0 words.

1,1-Dimethylhydrazine, also known as unsymdimethylhydrazine (UDMH) and vinyl acetate (VA), are both classified by the International Agency for Research on Cancer as 2B carcinogens (possibly...

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Effect of PSC 833, an inhibitor of P-glycoprotein, on 1,2-dimethylhydrazine-induced liver carcinogenesis in rats

Janarthanan Kankesan, Aroon Yusuf, Ezio Laconi, Ramesh Vanama, Grace Bradley, Jake J. Thiessen, Victor Ling, Prema M. Rao, Srinivasan Rajalakshmi and Dittakavi S. R. Sarma.

in Carcinogenesis

December 2003; p ublished online December 2003 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 6213 words.

The present study explores the hypothesis that over-expression of P-glycoprotein (Pgp, product of mdr1) is intimately associated with liver cancer development and therefore inhibitors of Pgp...

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Increased induction of aberrant crypt foci by 1,2-dimethylhydrazine in rats fed diets containing purified genistein or genistein-rich soya protein

J.M. Gee, H.P.J.M. Noteborn, A.C.J. Polley and I.T. Johnson.

in Carcinogenesis

December 2000; p ublished online December 2000 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 4368 words.

The isoflavonoid genistein inhibits mitosis and increases apoptosis in a variety of tumour cell lines in vitro, and may exert anticarcinogenic effects in vivo. To assess its effects on the...

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Chronic Trypanosoma cruzi infection associated with low incidence of 1,2-dimethylhydrazine-induced colon cancer in rats

E.C. Oliveira, M.S.B. Leite, J.A.R. Miranda, A.L.S.S. Andrade, S.B. Garcia, A.O. Luquetti and H. Moreira.

in Carcinogenesis

May 2001; p ublished online May 2001 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 3740 words.

Experimental data have demonstrated that chronic infection with intracellular parasites may enhance resistance against some types of tumour. This phenomenon has not yet been demonstrated for...

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Dietary n-3 PUFA increases the apoptotic response to 1,2-dimethylhydrazine, reduces mitosis and suppresses the induction of carcinogenesis in the rat colon

Peter Latham, Elizabeth K. Lund and Ian T. Johnson.

in Carcinogenesis

April 1999; p ublished online April 1999 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 4829 words.

The effect of dietary fish oil on colonic crypt cell apoptosis and proliferation was examined in male Wistar rats, 24 and 48 h after administration of 1,2-dimethylhydrazine (DMH), and its...

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CANCER BIOLOGY: Endogenous antioxidant status in neoplastic and adjacent tissues in 1,2-dimethylhydrazine-induced colon cancer in rats: effects of olsalazine

Mohammed H. Moghadasian, Hugh J. Freeman and David V. Godin.

in Carcinogenesis

May 1996 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 0 words.

There is much evidence suggesting a possible role of reactive oxygen-derived substances in the pathogenesis of both ulcerative colitis and colon cancer. The antioxidant effects of...

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