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ADPKD

Overview page. Subjects: Chemistry.

abbr. for autosomal dominant polycystic kidney disease.

See overview in Oxford Index

ADPKD

Overview page. Subjects: Chemistry.

abbr. for autosomal dominant polycystic kidney disease.

See overview in Oxford Index

ADPKD

Edited by Richard Cammack, Teresa Atwood, Peter Campbell, Howard Parish, Anthony Smith, Frank Vella and John Stirling.

in Oxford Dictionary of Biochemistry and Molecular Biology

January 2006; p ublished online January 2008 .

Reference Entry. Subjects: Biochemistry. 8 words.

abbr. for autosomal dominant polycystic kidney disease.

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Hypertension in autosomal-dominant polycystic kidney disease (ADPKD)

Laia Sans-Atxer, Roser Torra and Patricia Fernández-Llama.

in Clinical Kidney Journal

October 2013; p ublished online April 2013 .

Journal Article. Subjects: Nephrology. 4502 words.

Cardiovascular (CV) complications are the major cause of death in autosomal-dominant polycystic kidney disease (ADPKD) patients. Hypertension is common in these patients even before the...

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Defects in cell polarity underlie TSC and ADPKD-associated cystogenesis

Cleo S. Bonnet, Mark Aldred, Christopher von Ruhland, Rebecca Harris, Richard Sandford and Jeremy P. Cheadle.

in Human Molecular Genetics

June 2009; p ublished online March 2009 .

Journal Article. Subjects: Genetics and Genomics. 5993 words.

Clinical trials are underway for the treatment of tuberous sclerosis (TSC)-associated tumours using mTOR inhibitors. Here, we show that many of the earliest renal lesions from Tsc1null...

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Building a network of ADPKD reference centres across Europe: the EuroCYST initiative

Katja Petzold, Ron T. Gansevoort, Albert C.M. Ong, Olivier Devuyst, Laura Rotar, Kai-Uwe Eckardt, Anna Köttgen, Yves Pirson, Giuseppe Remuzzi, Richard Sandford, Vladimir Tesar, Tevfik Ecder, Dominique Chaveau, Roser Torra, Klemens Budde, Yannick Le Meur, Rudolf P. Wüthrich and Andreas L. Serra.

in Nephrology Dialysis Transplantation

September 2014; p ublished online September 2014 .

Journal Article. Subjects: Nephrology. 3757 words.

Background

Autosomal dominant polycystic kidney disease (ADPKD) is the most common monogenic inherited kidney disease, affecting an estimated 600 000...

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European ADPKD Forum multidisciplinary position statement on autosomal dominant polycystic kidney disease care

Tess Harris and Richard Sandford.

in Nephrology Dialysis Transplantation

April 2018; p ublished online December 2017 .

Journal Article. Subjects: Nephrology. 7798 words.

Abstract

Autosomal dominant polycystic kidney disease (ADPKD) is a chronic, progressive condition characterized by the development and growth of cysts in the...

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Therapeutic targeting of BET bromodomain protein, Brd4, delays cyst growth in ADPKD

Xia Zhou, Lucy X. Fan, Dorien J. M. Peters, Marie Trudel, James E. Bradner and Xiaogang Li.

in Human Molecular Genetics

July 2015; p ublished online April 2015 .

Journal Article. Subjects: Genetics and Genomics. 7514 words.

In this study, we identified a BET bromodomain (BRD) protein, Brd4, not only as a novel epigenetic regulator of autosomal dominant polycystic kidney disease (ADPKD) but also as a novel...

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Bilineal inheritance of type 1 autosomal dominant polycystic kidney disease (ADPKD) and recurrent fetal loss

Ramón Peces, Carlos Peces, Eliecer Coto and Rafael Selgas.

in Clinical Kidney Journal

October 2008; p ublished online July 2008 .

Journal Article. Subjects: Nephrology. 1509 words.

We report for the first time a family with type 1 ADPKD in which the marriage between affected non-consanguinous individuals resulted in two live-born heterozygous offspring and two fetuses...

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The effect of eicosapentaenoic acid on renal function and volume in patients with ADPKD

Eiji Higashihara, Kikuo Nutahara, Shigeo Horie, Satoru Muto, Tatsuo Hosoya, Kazushige Hanaoka, Ken Tuchiya, Kouichi Kamura, Kenmei Takaichi, Yoshifumi Ubara, Miho Itomura and Tomohito Hamazaki.

in Nephrology Dialysis Transplantation

September 2008; p ublished online March 2008 .

Journal Article. Subjects: Nephrology. 3372 words.

Background. Soy protein ameliorates rat polycystic kidney disease with concomitant renal enrichment of ω3-polyunsaturated fatty acids. A study was conducted to examine the...

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Triptolide reduces cyst formation in a neonatal to adult transition <i>Pkd1</i> model of ADPKD

Stephanie J. Leuenroth, Natasha Bencivenga, Halima Chahboune, Fahmeed Hyder and Craig M. Crews.

in Nephrology Dialysis Transplantation

July 2010; p ublished online February 2010 .

Journal Article. Subjects: Nephrology. 5233 words.

Background. Autosomal dominant polycystic kidney disease (ADPKD), a major cause of end-stage renal failure, results from genetic mutation of either polycystin-1 (Pkd1) or...

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