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Overview page. Subjects: Music.

Opera in three acts by Brett Dean to a libretto by Amanda Holden after Peter Carey's novel (1981) (Sydney, 2010).

See overview in Oxford Index

Household and Dwelling Contact as Risk Factors for Leprosy in Northern Malawi

P. E. M. Fine, J. A. C. Steme, J. M. Pönnighaus, L. Bliss, J. Saul, A. Chihana, M. Munthali and D. K. Wamdorff.

in American Journal of Epidemiology

July 1997; p ublished online July 1997 .

Journal Article. Subjects: Public Health and Epidemiology. 0 words.

Data on household and dwelling contact with known leprosy cases were available on more than 80,000 initially disease-free individuals followed up during the 1980s in a rural district of...

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Prognostic and predictive value of ERβ1 and ERβ2 in the Intergroup Exemestane Study (IES)—first results from PathIES

V. Speirs, G. Viale, K. Mousa, C. Palmieri, S. N. Reed, H. Nicholas, M. Cheang, J. Jassem, P. E. Lønning, E. Kalaitzaki, C. J. H. van de Velde, B. B. Rasmussen, D. M. Verhoeven, A. M. Shaaban, J. M. S. Bartlett, J. M. Bliss and R. C. Coombes.

in Annals of Oncology

September 2015; p ublished online May 2015 .

Journal Article. Subjects: Medical Oncology. 3240 words.


Intergroup Exemestane Study (IES) was a randomised study that showed a survival benefit of switching adjuvant endocrine therapy after 2–3 years...

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Guidelines for time-to-event end point definitions in breast cancer trials: results of the DATECAN initiative (Definition for the Assessment of Time-to-event Endpoints in CANcer trials)

S. Gourgou-Bourgade, D. Cameron, P. Poortmans, B. Asselain, D. Azria, F. Cardoso, R. A'Hern, J. Bliss, J. Bogaerts, H. Bonnefoi, E. Brain, M. J. Cardoso, B. Chibaudel, R. Coleman, T. Cufer, L. Dal Lago, F. Dalenc, E. De Azambuja, M. Debled, S. Delaloge, T. Filleron, J. Gligorov, M. Gutowski, W. Jacot, C. Kirkove, G. MacGrogan, S. Michiels, I. Negreiros, B. V. Offersen, F. Penault Llorca, G. Pruneri, H. Roche, N. S. Russell, F. Schmitt, V. Servent, B. Thürlimann, M. Untch, J. A. van der Hage, G. van Tienhoven, H. Wildiers, J. Yarnold, F. Bonnetain, S. Mathoulin-Pélissier, C. Bellera and T. S. Dabakuyo-Yonli.

in Annals of Oncology

December 2015; p ublished online October 2015 .

Journal Article. Subjects: Medical Oncology. 274 words.

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Extreme chromosomal instability forecasts improved outcome in ER-negative breast cancer: a prospective validation cohort study from the TACT trial

M. Jamal-Hanjani, R. A'Hern, N. J. Birkbak, P. Gorman, E. Grönroos, S. Ngang, P. Nicola, L. Rahman, E. Thanopoulou, G. Kelly, P. Ellis, P. Barrett-Lee, S. R. D. Johnston, J. Bliss, R. Roylance and C. Swanton.

in Annals of Oncology

July 2015; p ublished online May 2015 .

Journal Article. Subjects: Medical Oncology. 4289 words.


Chromosomal instability (CIN) has been shown to be associated with drug resistance and poor clinical outcome in several cancer types. However, in...

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A randomised comparative trial of infusional ECisF versus conventional FEC as adjuvant chemotherapy in early breast cancer: the TRAFIC trial

B. Sirohi, R. A'Hern, G. Coombes, J. M. Bliss, T. Hickish, T. Perren, M. Crawford, M. O'Brien, T. Iveson, S. Ebbs, A. Skene, R. Laing and I. E. Smith.

in Annals of Oncology

August 2010; p ublished online January 2010 .

Journal Article. Subjects: Medical Oncology. 3288 words.

Background: The epirubicin with cisplatin and infusional 5-fluorouracil (5-FU) (ECisF) regimen was found to be highly active in the treatment of metastatic breast cancer and as...

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Long-term endometrial effects in postmenopausal women with early breast cancer participating in the Intergroup Exemestane Study (IES)—a randomised controlled trial of exemestane versus continued tamoxifen after 2–3 years tamoxifen

G. Bertelli, E. Hall, E. Ireland, C. F. Snowdon, J. Jassem, K. Drosik, H. Karnicka-Mlodkowska, R. C. Coombes and J. M. Bliss.

in Annals of Oncology

March 2010; p ublished online August 2009 .

Journal Article. Subjects: Medical Oncology. 4467 words.

Background: The antiestrogen tamoxifen may have partial estrogen-like effects on the postmenopausal uterus. Aromatase inhibitors (AIs) are increasingly used after initial...

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A novel continuous infusional 5-fluorouracil-based chemotherapy regimen compared with conventional chemotherapy in the neo-adjuvant treatment of early breast cancer: 5 year results of the TOPIC trial

I. E. Smith, R. P. A’Hern, G. A. Coombes, A. Howell, S. R. Ebbs, T. F. Hickish, M. E. R. O’Brien, J. L. Mansi, C. B. Wilson, A. C. Robinson, P. A. Murray, C. G. A. Price, T. J. Perren, R. W. Laing and J. M. Bliss.

in Annals of Oncology

May 2004; p ublished online May 2004 .

Journal Article. Subjects: Medical Oncology. 4750 words.


To compare the efficacy of continuous infusional 5-fluorouracil (5-FU)-based chemotherapy against conventional bolus chemotherapy in the...

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High dose chemotherapy and autologous stem cell transplantation as adjuvant therapy for primary breast cancer patients with four or more lymph nodes involved: long-term results of an international randomised trial

R. C. Coombes, A. Howell, M. Emson, C. Peckitt, C. Gallagher, C. Bengala, A. Tres, R. Welch, P. Lawton, R. Rubens, E. Woods, J. Haviland, D. Vigushin, E. Kanfer and J. M. Bliss.

in Annals of Oncology

May 2005; p ublished online May 2005 .

Journal Article. Subjects: Medical Oncology. 6069 words.

Background:: The purpose of this study was to assess whether a short course of anthracycline containing chemotherapy followed by high dose therapy with autologous stem-cell...

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Randomized phase III trials of adjuvant FAMTX or FEMTX compared with surgery alone in resected gastric cancer. A combined analysis of the EORTC GI Group and the ICCG

D. Nitti, J. Wils, J. Guimaraes Dos Santos, G. Fountzilas, P. F. Conte, C. Sava, A. Tres, R. C. Coombes, D. Crivellari, A. Marchet, E. Sanchez, J. M. Bliss, J. Homewood, M. L. Couvreur, E. Hall, B. Baron, E. Woods, M. Emson, E. Van Cutsem and M. Lise.

in Annals of Oncology

February 2006; p ublished online November 2005 .

Journal Article. Subjects: Medical Oncology. 4978 words.

Background: In patients who underwent radical resection for gastric cancer, we investigate the relative efficacy of combined 5-fluorouracil + adriamycin or epirubicin and...

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Neoadjuvant vinorelbine/epirubicin (VE) versus standard adriamycin/cyclophosphamide (AC) in operable breast cancer: analysis of response and tolerability in a randomised phase III trial (TOPIC 2)

S. Chua, I. E. Smith, R. P. A'Hern, G. A. Coombes, T. F. Hickish, A. C. Robinson, R. W. Laing, M. E. R. O'Brien, S. R. Ebbs, A. Hong, A. Wardley, T. Mughal, M. Verrill, D. Dubois and J. M. Bliss.

in Annals of Oncology

September 2005; p ublished online September 2005 .

Journal Article. Subjects: Medical Oncology. 4861 words.

Background: Vinorelbine is active and well tolerated against advanced breast cancer but there are no published efficacy studies in early breast cancer. We have therefore carried...

Go to Oxford Journals »  abstract