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E-site

Overview page. Subjects: Chemistry — Medicine and Health.

The ribosomal site that binds deacylated tRNA after it leaves the P-site and before it leaves the ribosome.

See overview in Oxford Index

E site

John Lackie.

in A Dictionary of Biomedicine

January 2010; p ublished online January 2010 .

Reference Entry. Subjects: Clinical Medicine. 20 words.

The *ribosomal site that binds deacylated tRNA after it leaves the *P-site and before it leaves the ribosome.

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eF-site and PDBjViewer: database and viewer for protein functional sites

Kengo Kinoshita and Haruki Nakamura.

in Bioinformatics

May 2004; p ublished online February 2004 .

Journal Article. Subjects: Bioinformatics and Computational Biology. 0 words.

Summary: The electrostatic-surface of functional site (eF-site) is a database for the molecular surfaces of protein functional sites. To enable browsing of each molecular...

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Solution measurement of DNA curvature in papillomavirus E2 binding sites

Jeff M. Zimmerman and L. James Maher III.

in Nucleic Acids Research

September 2003; p ublished online September 2003 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 4002 words.

‘Indirect readout’ refers to the proposal that proteins can recognize the intrinsic three‐dimensional shape or flexibility of a DNA binding sequence apart from direct protein contact with...

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Function of the ribosomal E-site: a mutagenesis study

Petr V. Sergiev, Dmitry V. Lesnyak, Sergey V. Kiparisov, Dmitry E. Burakovsky, Andrei A. Leonov, Alexey A. Bogdanov, Richard Brimacombe and Olga A. Dontsova.

in Nucleic Acids Research

January 2005; p ublished online January 2005 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 7707 words.

Ribosomes synthesize proteins according to the information encoded in mRNA. During this process, both the incoming amino acid and the nascent peptide are bound to tRNA molecules. Three...

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Prediction of an anti-IgE binding site on IgE.

J D Wright and C Lim.

in Protein Engineering, Design and Selection

June 1998; p ublished online June 1998 .

Journal Article. Subjects: Proteins. 0 words.

A combination of computation techniques have been used to determine the binding site and amino acid residues on IgE that are critical for binding to a therapeutic anti-IgE. Homology...

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Mapping of the second tetracycline binding site on the ribosomal small subunit of <i>E.coli</i>

Maria M. Anokhina, Andrea Barta, Knud H. Nierhaus, Vera A. Spiridonova and Alexei M. Kopylov.

in Nucleic Acids Research

April 2004; p ublished online April 2004 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 3134 words.

Tetracycline blocks stable binding of aminoacyl‐tRNA to the bacterial ribosomal A‐site. Various tetracycline binding sites have been identified in crystals of the 30S ribosomal small subunit...

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E1DS: catalytic site prediction based on 1D signatures of concurrent conservation

Ting-Ying Chien, Darby Tien-Hao Chang, Chien-Yu Chen, Yi-Zhong Weng and Chen-Ming Hsu.

in Nucleic Acids Research

July 2008; p ublished online June 2008 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 3457 words.

Large-scale automatic annotation of protein sequences remains challenging in postgenomics era. E1DS is designed for annotating enzyme sequences based on a repository of 1D signatures. The...

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Deacylated tRNA is released from the E site upon A site occupation but before GTP is hydrolyzed by EF-Tu

George Dinos, Dimitrios L. Kalpaxis, Daniel N. Wilson and Knud H. Nierhaus.

in Nucleic Acids Research

January 2005; p ublished online January 2005 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 4574 words.

The presence or absence of deacylated tRNA at the E site sharply influences the activation energy required for binding of a ternary complex to the ribosomal A site indicating the different...

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Evaluating the online activity of users of the e-Bug web site

Ed de Quincey, Patty Kostkova, Gawesh Jawaheer, David Farrell, Cliodna A. M. McNulty and Julius Weinberg.

in Journal of Antimicrobial Chemotherapy

June 2011; p ublished online June 2011 .

Journal Article. Subjects: Medical Oncology; Critical Care. 2526 words.

Web server log analysis is being increasingly used to evaluate the user behaviour on healthcare resource web sites due to the detailed record of activity that they contain. This study aimed...

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Conformational model for binding site recognition by the <i>E.coli</i> MetJ transcription factor

Rongxiang Liu, Thomas W. Blackwell and David J. States.

in Bioinformatics

July 2001; p ublished online July 2001 .

Journal Article. Subjects: Bioinformatics and Computational Biology. 0 words.

Motivation: Current methods for identifying sequence specific binding sites in DNA sequence using position specific weight matrices are limited in both sensitivity and specificity....

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