in American Journal of Epidemiology
March 2008; p ublished online December 2007 .
Journal Article. Subjects: Public Health and Epidemiology. 4469 words.
Physical inactivity and high mammographic breast density have both been associated with increased breast cancer risk. However, the association between physical activity and mammographic...
Final results of the TANIA randomised phase III trial of bevacizumab after progression on first-line bevacizumab therapy for HER2-negative locally recurrent/metastatic breast cancer
in Annals of Oncology
November 2016; p ublished online August 2016 .
Journal Article. Subjects: Medical Oncology. 3856 words.
The randomised phase III TANIA trial demonstrated that continuing bevacizumab with second-line chemotherapy for locally recurrent/metastatic...
March 2017; p ublished online December 2016 .
Journal Article. Subjects: Bioinformatics and Computational Biology. 7595 words.
Motivation: Testing SNP–SNP interactions is considered as a key for overcoming bottlenecks of genetic association studies. However,...
July 2005; p ublished online April 2005 .
Journal Article. Subjects: Neurology; Neuroscience. 5929 words.
Relatives of people with aneurysmal subarachnoid haemorrhage (SAH) may be at increased risk of SAH, but precise data on the level of risk and which relatives are most likely to be affected...
February 2000; p ublished online February 2000 .
Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 3992 words.
The aromatase enzyme catalyses the conversion of androgens to oestrogens in the oestrogen biosynthesis pathway. Because increased exposure to oestrogens is considered to be a risk factor for...
November 2001; p ublished online November 2001 .
Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 3331 words.
Several studies have investigated polymorphisms in CYP1A1 and breast cancer risk with inconsistent results. We have carried out a population based case–control study of the Thr461Asn and...
November 1999; p ublished online November 1999 .
Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 3953 words.
Endogenous hormone exposure is known to alter breast cancer susceptibility and genes responsive to such hormones are plausible candidates for predisposition genes. We have examined...
P ublished online February 2006 .
Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 6961 words.
Epigenetic events, resulting changes in gene expression capacity, are important in tumour progression, and variation in genes involved in epigenetic mechanisms might therefore be important...
P ublished online June 2006 .
Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 7306 words.
Mismatch repair (MMR) is important for repairing of nucleotide mismatches during DNA replication. Germline mutations in MMR genes are associated with hereditary non-polyposis colorectal...
Association of single-nucleotide polymorphisms in the cell cycle genes with breast cancer in the British population
February 2008; p ublished online January 2008 .
Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 5495 words.
Using a large-scale case–control study, we examined whether common single-nucleotide polymorphisms (SNPs) within 13 genes involved in the cell cycle pathway are associated with breast...