Cyclooxygenase-2 inhibition improves amyloid-β-mediated suppression of memory and synaptic plasticity
March 2008; p ublished online March 2008 .
Journal Article. Subjects: Neurology; Neuroscience. 8004 words.
Non-steroidal anti-inflammatory agents (NSAIDs) are associated with a marked reduction in the risk of developing Alzheimer's disease, a form of dementia characterized by the accumulation of...
August 2011; p ublished online July 2011 .
Journal Article. Subjects: Neurology; Neuroscience. 9322 words.
Morphine is endogenously synthesized in the central nervous system and endogenous dopamine is thought to be necessary for endogenous morphine formation. As Parkinson's disease results from...
p21, p27 and p53 in estrogen and antiprogestin-induced tumor regression of experimental mouse mammary ductal carcinomas
May 2002; p ublished online May 2002 .
Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 7100 words.
Metastatic mammary carcinoma tumor lines 59-2-HI and C7-2-HI originated in female BALB/c mice treated with medroxyprogesterone acetate and are maintained by syngeneic transplantation. Both...
in Cardiovascular Research
January 2011; p ublished online August 2010 .
Journal Article. Subjects: Cardiovascular Medicine. 7281 words.
Increased numbers of mast cells have been reported in explanted human hearts with dilated cardiomyopathy and in animal models of experimentally induced hypertension, myocardial infarction,...
in Cardiovascular Research
December 2011; p ublished online September 2011 .
Journal Article. Subjects: Cardiovascular Medicine. 5017 words.
Substance P and neurokinin A (NKA) are sensory nerve neuropeptides encoded by the TAC1 gene. Substance P is a mast cell secretagogue and mast cells are...
The non-obese diabetic mouse sequence, annotation and variation resource: an aid for investigating type 1 diabetes
P ublished online May 2013 .
Journal Article. Subjects: Bioinformatics and Computational Biology; Ecology and Conservation; Evolutionary Biology. 6430 words.
Model organisms are becoming increasingly important for the study of complex diseases such as type 1 diabetes (T1D). The non-obese diabetic (NOD) mouse is an experimental model for T1D...
in EP Europace
January 2014; p ublished online July 2013 .
Journal Article. Subjects: Cardiovascular Medicine. 4312 words.
Drug-induced long QT syndrome (diLQTS) leading to Torsade de Pointes (TdP) is a potentially lethal condition, which has led to several post-marketing...
Social isolation, vital exhaustion, and incident heart failure: findings from the Atherosclerosis Risk in Communities Study
in European Journal of Heart Failure
July 2012; p ublished online May 2012 .
Journal Article. Subjects: Cardiovascular Medicine. 4334 words.
Prospective studies have shown that social isolation (i.e. lack of social contacts) predicts incident coronary heart disease (CHD), but it is unclear...
German GPs' willingness to expand roles of physician assistants: a regional survey of perceptions and informal practices influencing uptake of health reforms in primary health care
in Family Practice
August 2012; p ublished online January 2012 .
Journal Article. Subjects: Primary Care. 3774 words.
Many countries with shortages in health personnel are introducing task shifting in primary health care. GPs’ attitudes and practices strongly...
Mitochondrial calcium uptake capacity as a therapeutic target in the R6/2 mouse model of Huntington's disease
in Human Molecular Genetics
September 2010; p ublished online June 2010 .
Journal Article. Subjects: Genetics and Genomics. 10966 words.
Huntington's disease (HD) is an incurable autosomal-dominant neurodegenerative disorder initiated by an abnormally expanded polyglutamine domain in the huntingtin protein. It is proposed...