Oxford Index Search Results

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HMG box

Overview page. Subjects: Medicine and Health.

A motif characteristic of high-mobility group proteins, a domain (79 aa) involved in binding linear DNA in a sequence-specific manner, causing it to bend through a large angle, thereby...

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Interactions between HMG boxes

Susann Taudte, Hong Xin, Anthony J. Bell and Neville R. Kallenbach.

in Protein Engineering, Design and Selection

December 2001; p ublished online December 2001 .

Journal Article. Subjects: Proteins. 5444 words.

Many proteins consist of subdomains that can fold and function independently. We investigate here the interaction between the two high mobility group (HMG) box subdomains of the nuclear...

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DNA binding by single HMG box model proteins

Hong Xin, Susann Taudte, Neville R. Kallenbach, M. Paullin Limbach and Richard S. Zitomer.

in Nucleic Acids Research

October 2000; p ublished online October 2000 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 5067 words.

The HMG1/2 family is a large group of proteins that share a conserved sequence of ∼80 amino acids rich in basic, aromatic and proline side chains, referred to as an HMG box. Previous studies...

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HMG box

Overview page. Subjects: Medicine and Health.

A motif characteristic of high-mobility group proteins, a domain (79 aa) involved in binding linear DNA in a sequence-specific manner, causing it to bend through a large angle, thereby...

See overview in Oxford Index

HMG box

John Lackie.

in A Dictionary of Biomedicine

January 2010; p ublished online January 2010 .

Reference Entry. Subjects: Clinical Medicine. 41 words.

A motif characteristic of *high-mobility group proteins, a domain (79 aa) involved in binding linear DNA in a

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HMG Box A in HMG2 Protein Functions as a Mediator of DNA Structural Alteration Together with Box B

Yasuyuki Nakamura, Ken-ichi Yoshioka, Hitoshi Shirakawa and Michiteru Yoshida.

in The Journal of Biochemistry

April 2001; p ublished online April 2001 .

Journal Article. Subjects: Biochemistry. 0 words.

Nonhistone protein HMG2, like HMG1, binds with B-DNA in a sequence-nonspecific manner and causes structural alterations in DNA such as bending, kinking and unwinding. Here, we studied the...

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The mechanism of sequence non-specific DNA binding of HMG1/2-box B in HMG1 with DNA

Kouhei Saito, Takeshi Kikuchi and Michiteru Yoshida.

in Protein Engineering, Design and Selection

March 1999; p ublished online March 1999 .

Journal Article. Subjects: Proteins. 5775 words.

The DNA binding mechanism of box B in HMG1, a member of the sequence non-specific DNA binding HMG1/2-box family of proteins, has been examined by both mutation analyses and molecular...

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HMG boxes of DSP1 protein interact with the Rel homology domain of transcription factors

M. Decoville, M. J. Giraud-Panis, C. Mosrin-Huaman, M. Leng and D. Locker.

in Nucleic Acids Research

January 2000; p ublished online January 2000 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 6545 words.

Formation of the dorsoventral axis in Drosophila melanogaster is mediated through control of the expression of several genes by the morphogen Dorsal. In the ventral part of the embryo Dorsal...

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High expression of the HMG box factor Sox-13 in arterial walls during embryonic development

Jeroen Roose, Wouter Korver, Ellis Oving, Anne Wilson, Gerry Wagenaar, Marry Markman, Wout Lamers and Hans Clevers.

in Nucleic Acids Research

January 1998; p ublished online January 1998 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 4028 words.

Members of the Sox gene family of transcription factors are defined by the presence of an 80 amino acid homology domain, the High Mobility Group (HMG) box.Here we report the cloning and...

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The DNA Supercoiling Architecture Induced by the Transcription Factor xUBF Requires Three of Its Five HMG-Boxes

V. Y. Stefanovsky, D. P. Bazett-Jones, G. Pelletier and T. Moss.

in Nucleic Acids Research

August 1996; p ublished online August 1996 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 4240 words.

The formation of a near complete loop of DNA is a striking property of the architectural HMG-box factor xUBF. Here we show that DNA looping only requires a dimer of Nbox13, a C-terminal...

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Mutagenesis Analysis of the Interaction between the Dorsal Rel Homology Domain and HMG Boxes of DSP1 Protein

Davy Martin, Anne Daulny, Martine Decoville and Daniel Locker.

in The Journal of Biochemistry

October 2003; p ublished online October 2003 .

Journal Article. Subjects: Biochemistry. 4735 words.

DSP1 is an HMG-like protein of Drosophila melanogaster consisting of 386 amino acids with two HMG domains at the C-terminal end. It was shown to interact with Dorsal protein through the HMG...

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The DNA Bend Angle and Binding Affinity of an HMG Box Increased by the Presence of Short Terminal Arms

Mirna Lnenicek-Allen, Christopher M. Read and Colyn Crane-Robinson.

in Nucleic Acids Research

March 1996; p ublished online March 1996 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 2864 words.

The HMG box of human LEF-1 (hLEF-1, formerly TCF1α) has been expressed in four forms: a parent box of 81 amino acids and constructs having either a 10 amino acid C-terminal extension, a 9...

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Dimerization and HMG box domains 1–3 present in <i>Xenopus</i> UBF are sufficient for its role in transcriptional enhancement

Gareth J. Sullivan and Brian McStay.

in Nucleic Acids Research

August 1998; p ublished online August 1998 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 5596 words.

Transcription of Xenopus ribosomal genes by RNA polymerase I is directed by a stable transcription complex that forms on the gene promoter. This complex is comprised of the HMG box factor...

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The SRY-HMG box gene, <i>SOX4</i>, is a target of gene amplification at chromosome 6p in lung cancer†

Pedro P. Medina, Sandra D. Castillo, Sandra Blanco, Marta Sanz-Garcia, Cristina Largo, Sara Alvarez, Jun Yokota, Ana Gonzalez-Neira, Javier Benitez, Hans C. Clevers, Juan C. Cigudosa, Pedro A. Lazo and Montse Sanchez-Cespedes.

in Human Molecular Genetics

April 2009; p ublished online January 2009 .

Journal Article. Subjects: Genetics and Genomics. 6262 words.

The search for oncogenes is becoming increasingly important in cancer genetics because they are suitable targets for therapeutic intervention. To identify novel oncogenes, activated by gene...

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The Stabilized Structural Array of Two HMGl/2–Boxes Endowed by a Linker Sequence between Them Is Requisite for the Effective Binding of HMG1 with DNA

Kouhei Saito, Takeshi Kikuchi, Hitoshi Shirakawa and Michiteru Yoshida.

in The Journal of Biochemistry

February 1999; p ublished online February 1999 .

Journal Article. Subjects: Biochemistry. 0 words.

High mobility group (HMG) protein 1 contains two DNA binding motifs, called HMG1/2–boxes, linked with a linker region. The functional relationships between the two boxes and the mechanism...

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HMG box transcription factor TCF‐4’s interaction with CtBP1 controls the expression of the Wnt target Axin2/Conductin in human embryonic kidney cells

Tomas Valenta, Jan Lukas and Vladimir Korinek.

in Nucleic Acids Research

May 2003; p ublished online May 2003 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 10207 words.

Members of the Tcf/Lef family of the HMG box transcription factors are nuclear effectors of the Wnt signal transduction pathway. Upon Wnt signaling, TCF/LEF proteins interact with β‐catenin...

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Two new novel point mutations localized upstream and downstream of the HMG box region of the <i>SRY</i> gene in three Indian 46,XY females with sex reversal and gonadal tumour formation

Mohammad Shahid, Varinderpal S. Dhillion, Neeraj Jain, Suresh Hedau, Sandhya Diwakar, Poonam Sachdeva, Swaraj Batra, B.C. Das and S.A. Husain.

in MHR: Basic science of reproductive medicine

July 2004; p ublished online July 2004 .

Journal Article. Subjects: Reproductive Medicine. 3836 words.

The Y chromosome-specific gene SRY is one of the key genes involved in human sex determination. The SRY gene encodes a testis-specific transcription factor that plays a key role in sexual...

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Analysis of Mitochondrial DNA Nucleoids in Wild-Type and a Mutant Strain of <i>Saccharomyces Cerevisiae</i> that Lacks the Mitochondrial HMG Box Protein Abf2p

Scott M. Newman, Olga Zelenaya-Troitskaya, Philip S. Perlman and Ronald A. Butow.

in Nucleic Acids Research

January 1996; p ublished online January 1996 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 6147 words.

DNA-protein complexes (nucleoids) are believed to be the segregating unit of mitochondrial DNA (mtDNA) in Saccharomyces cerevisiae. A mitochondrial HMG box protein, Abf2p, is needed for...

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All Tcf HMG box transcription factors interact with Groucho-related co-repressors

Helen Brantjes, Jeroen Roose, Marc van de Wetering and Hans Clevers.

in Nucleic Acids Research

April 2001; p ublished online April 2001 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 6342 words.

Tcf/Lef family transcription factors are the downstream effectors of the Wingless/Wnt signal transduction pathway. Upon Wingless/Wnt signalling, β-catenin translocates to the nucleus,...

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Developmentally-regulated packaging of mitochondrial DNA by the HMG-box protein mtTFA during <i>Xenopus </i>oogenesis

Ellen L. Shen and Daniel F. Bogenhagen.

in Nucleic Acids Research

July 2001; p ublished online July 2001 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 4941 words.

Mature Xenopus oocytes are highly enriched for mitochondria. The organelles are stored and partitioned to newly-arising cells during embryogenesis, when there is little mitochondrial DNA...

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Structure-function analysis of Hmo1 unveils an ancestral organization of HMG-Box factors involved in ribosomal DNA transcription from yeast to human

Benjamin Albert, Christine Colleran, Isabelle Léger-Silvestre, Axel B. Berger, Christophe Dez, Christophe Normand, Jorge Perez-Fernandez, Brian McStay and Olivier Gadal.

in Nucleic Acids Research

December 2013; p ublished online September 2013 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 8231 words.

Ribosome biogenesis is a major metabolic effort for growing cells. In Saccharomyces cerevisiae, Hmo1, an abundant high-mobility group box protein (HMGB) binds to the coding region of the...

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