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Mani

Overview page. Subjects: Medieval and Renaissance History (500 to 1500).

(Μάνη, Μαΐνη), the mountainous central “finger” of the Peloponnesos extending southward into the Cretan Sea and terminating in Cape Tainaron (Matapan). The region has an unusually rough and...

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A framework for installable external tools in Skyline

Daniel Broudy, Trevor Killeen, Meena Choi, Nicholas Shulman, Deepak R. Mani, Susan E. Abbatiello, Deepak Mani, Rushdy Ahmad, Alexandria K. Sahu, Birgit Schilling, Kaipo Tamura, Yuval Boss, Vagisha Sharma, Bradford W. Gibson, Steven A. Carr, Olga Vitek, Michael J. MacCoss and Brendan MacLean.

in Bioinformatics

January 2014; p ublished online May 2014 .

Journal Article. Subjects: Bioinformatics and Computational Biology. 1493 words.

Summary: Skyline is a Windows client application for targeted proteomics method creation and quantitative data analysis. The Skyline document model contains extensive mass...

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COMBINATION PHARMACOTHERAPY: A MIXTURE OF SMALL DOSES OF NALTREXONE, FLUOXETINE, AND A THYROTROPIN-RELEASING HORMONE ANALOGUE REDUCES ALCOHOL INTAKE IN THREE STRAINS OF ALCOHOL-PREFERRING RATS

Amir H. Rezvani, David H. Overstreet, George A. Mason, David S. Janowsky, Mani Hamedi, E. Clark and Ying Yang.

in Alcohol and Alcoholism

January 2000; p ublished online January 2000 .

Journal Article. Subjects: Public Health and Epidemiology. 5520 words.

It is common to treat some diseases with more than one medication simultaneously. Since more than one neurotransmitter system is involved in alcohol-seeking behaviour, then a therapeutic...

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Promoter Polymorphism rs886205 Genotype Interacts With DNA Methylation of the ALDH2 Regulatory Region in Alcohol Dependence

Hansi Pathak, Helge Frieling, Stefan Bleich, Alexander Glahn, Annemarie Heberlein, Mani Haschemi Nassab, Thomas Hillemacher, Alexandra Burkert and Mathias Rhein.

in Alcohol and Alcoholism

May 2017; p ublished online January 2017 .

Journal Article. Subjects: Public Health and Epidemiology. 5485 words.

Abstract

Aims

Aldehyde dehydrogenase 2 (ALDH2) protects cells from ethanol toxicity by metabolizing acetaldehyde....

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Pharmacokinetic and safety study of subcutaneously administered weekly ING-1, a human engineered™ monoclonal antibody targeting human EpCAM, in patients with advanced solid tumors

S. Goel, R. J. Bauer, K. Desai, A. Bulgaru, T. Iqbal, B.-K. Strachan, G. Kim, A. Kaubisch, G. F. Vanhove, G. Goldberg and S. Mani.

in Annals of Oncology

October 2007; p ublished online August 2007 .

Journal Article. Subjects: Medical Oncology. 2002 words.

Background: ING-1 is a high-affinity, human engineered™ monoclonal antibody that recognizes a 40 kilodalton epithelial cell adhesion molecule (EpCAM) glycoprotein that is...

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Phase I clinical study of infusional 5-fluorouracil with oxaliplatin and gemcitabine (FOG regimen) in patients with solid tumors

S. Goel, A. Bulgaru, H. Hochster, S. Wadler, W. Zamboni, M. Egorin, P. Ivy, L. Leibes, F. Muggia, G. Lockwood, E. Harvey, G. Renshaw and S. Mani.

in Annals of Oncology

November 2003; p ublished online November 2003 .

Journal Article. Subjects: Medical Oncology. 3402 words.

Background:

The aim of this study was to determine the maximum tolerated dose, recommended phase II dose (RPTD) and toxicities of the FOG regimen (infusional...

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Peripheral blood mononuclear and tumor cell pharmacodynamics of the novel epothilone B analogue, ixabepilone

S Mani, HM McDaid, A Grossman, F Muggia, S Goel, T Griffin, D Colevas, SB Horwitz and MJ Egorin.

in Annals of Oncology

January 2007; p ublished online October 2006 .

Journal Article. Subjects: Medical Oncology. 3791 words.

Background: We previously demonstrated that peak microtubule bundle formation (MBF) in peripheral blood mononuclear cells (PBMCs) occurs at the end of drug infusion and...

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Novel neurosensory testing in cancer patients treated with the epothilone B analog, ixabepilone

S. Goel, G. L. Goldberg, D. Y.-S. Kuo, F. Muggia, J. Arezzo and S. Mani.

in Annals of Oncology

December 2008; p ublished online July 2008 .

Journal Article. Subjects: Medical Oncology. 3439 words.

Background: We have previously established the recommended phase II dose (RPTD) of ixabepilone as 40 mg/m2 administered over 1 h repeated every 3 weeks with neuropathy as a...

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A multicenter phase II study of a five-day regimen of oral 5-fluorouracil plus eniluracil with or without leucovorin in patients with metastatic colorectal cancer

R. L. Schilsky, R. Bukowski, H. Burris, H. Hochster, M. O'Rourke, J. G. Wall, S. Mani, T. Bonny, J. Levin and J. Hohneker.

in Annals of Oncology

April 2000; p ublished online April 2000 .

Journal Article. Subjects: Medical Oncology. 0 words.

Purpose: To evaluate the safety and efficacy of a five-day regimen of oral 5-fluorouracil (5-FU) plus eniluracil (776C85) in patients with metastatic colorectal cancer (CRC).

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Phase II trial of uracil/tegafur (UFT) plus leucovorin in patients with advanced pancreatic carcinoma: A University of Chicago phase II consortium study

S. Mani, J. W. Kugler, D. F. Sciortino, J. C. Garcia, R. H. Ansari, R. Humerickhouse, F. Michelassi, M. C. Posner, K. L. Shulman, R. L. Schilsky, M. List, E. E. Vokes and S. Benner.

in Annals of Oncology

September 1998; p ublished online September 1998 .

Journal Article. Subjects: Medical Oncology. 0 words.

Background/objectives: Uracil and tegafur in a 4:1 molar concentration ratio (UFT; Bristol-Myers Squibb, Wallingford, CT) has broad anti-tumor activity for cancers arising from...

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Contralesional motor deficits after unilateral stroke reflect hemisphere-specific control mechanisms

Saandeep Mani, Pratik K. Mutha, Andrzej Przybyla, Kathleen Y. Haaland, David C. Good and Robert L. Sainburg.

in Brain

April 2013; p ublished online January 2013 .

Journal Article. Subjects: Neurology; Neuroscience. 9770 words.

We have proposed a model of motor lateralization, in which the left and right hemispheres are specialized for different aspects of motor control: the left hemisphere for predicting and...

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