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TetA

Overview page. Subjects: Chemistry.

A membrane‐associated protein of Gram‐negative bacteria that exports tetracycline from the bacterial cell thereby conferring antibiotic resistance. It is under the control of the...

See overview in Oxford Index

TetA

Overview page. Subjects: Chemistry.

A membrane‐associated protein of Gram‐negative bacteria that exports tetracycline from the bacterial cell thereby conferring antibiotic resistance. It is under the control of the...

See overview in Oxford Index

Suppression of gene expression by a cell‐permeable Tet repressor

Alison Mortlock, Walter Low and Andrea Crisanti.

in Nucleic Acids Research

December 2003; p ublished online December 2003 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 5617 words.

Engineered transcription factors designed to selectively activate or repress endogenous genes have great potential in medical and biotechnological applications. Ultimately, their success...

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Identification of Tet45, a tetracycline efflux pump, from a poultry-litter-exposed soil isolate and persistence of <i>tet</i>(45) in the soil

Yaqi You, Markus Hilpert and Mandy J. Ward.

in Journal of Antimicrobial Chemotherapy

September 2013; p ublished online April 2013 .

Journal Article. Subjects: Medical Oncology; Critical Care. 4866 words.

Objectives

To characterize a tetracycline resistance (TcR) determinant, closely related to the TetL efflux pump, in a Bhargavaea cecembensis strain...

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Minocycline resistance in an oral <i>Streptococcus infantis</i> isolate is encoded by <i>tet</i>(S) on a novel small, low copy number plasmid

Lena Ciric, Michael S. M. Brouwer, Peter Mullany and Adam P. Roberts.

in FEMS Microbiology Letters

April 2014; p ublished online April 2014 .

Journal Article. 4454 words.

Minocycline resistance in an oral bacteria, Streptococcus infantis, is mediated by a plasmid-encoded tet(S) gene which can excise from the plasmid with an IS element.

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Structure of <i>Naegleria</i> Tet-like dioxygenase (NgTet1) in complexes with a reaction intermediate 5-hydroxymethylcytosine DNA

Hideharu Hashimoto, June E. Pais, Nan Dai, Ivan R. Corrêa, Xing Zhang, Yu Zheng and Xiaodong Cheng.

in Nucleic Acids Research

December 2015; p ublished online August 2015 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 6082 words.

The family of ten-eleven translocation (Tet) dioxygenases is widely distributed across the eukaryotic tree of life, from mammals to the amoeboflagellate Naegleria gruberi. Like mammalian...

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TET1 is a maintenance DNA demethylase that prevents methylation spreading in differentiated cells

Chunlei Jin, Yue Lu, Jaroslav Jelinek, Shoudan Liang, Marcos R.H. Estecio, Michelle Craig Barton and Jean-Pierre J. Issa.

in Nucleic Acids Research

June 2014; p ublished online May 2014 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 10248 words.

TET1 is a 5-methylcytosine dioxygenase and its DNA demethylating activity has been implicated in pluripotency and reprogramming. However, the precise role of TET1 in DNA methylation...

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Expression of the <i>tetA</i>(C) tetracycline efflux pump in <i>Escherichia coli</i> confers osmotic sensitivity

Tom A. Stavropoulos and Craig A. Strathdee.

in FEMS Microbiology Letters

September 2000; p ublished online January 2006 .

Journal Article. 1655 words.

Expression of tetA(C) in Escherichia coli confers resistance to tetracycline as well as sensitivity to nickel and cadmium salts, lipophilic chelating agents, and aminoglycoside antibiotics....

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Hypomethylation of TET2 Target Genes Identifies a Curable Subset of Acute Myeloid Leukemia

Jumpei Yamazaki, Rodolphe Taby, Jaroslav Jelinek, Noel J. M. Raynal, Matteo Cesaroni, Sherry A. Pierce, Steven M. Kornblau, Carlos E. Bueso-Ramos, Farhad Ravandi, Hagop M. Kantarjian and Jean-Pierre J. Issa.

in JNCI: Journal of the National Cancer Institute

P ublished online November 2015 .

Journal Article. Subjects: Medical Oncology. 6293 words.

Background:

Acute myeloid leukemia (AML) is curable in a subset of cases. The DNA methylation regulator TET2 is frequently mutated in AML, and we...

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Identification of a melanoma susceptibility locus and somatic mutation in <i>TET2</i>

Fengju Song, Christopher I. Amos, Jeffrey E. Lee, Christine G. Lian, Shenying Fang, Hongliang Liu, Stuart MacGregor, Mark M. Iles, Matthew H. Law, Neal I. Lindeman, Grant W. Montgomery, David L. Duffy, Anne E. Cust, Mark A. Jenkins, David C. Whiteman, Richard F. Kefford, Graham G. Giles, Bruce K. Armstrong, Joanne F. Aitken, John L. Hopper, Kevin M. Brown, Nicholas G. Martin, Graham J. Mann, D.Timothy Bishop, Julia A.Newton Bishop, Peter Kraft, Abrar A. Qureshi, Peter A. Kanetsky, Nicholas K. Hayward, David J. Hunter, Qingyi Wei and Jiali Han.

in Carcinogenesis

September 2014; p ublished online June 2014 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 4272 words.

Although genetic studies have reported a number of loci associated with melanoma risk, the complex genetic architecture of the disease is not yet fully understood. We sought to identify...

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A TetR-like regulator broadly affects the expressions of diverse genes in <i>Mycobacterium smegmatis</i>

Min Yang, Chunhui Gao, Tao Cui, Jingning An and Zheng-Guo He.

in Nucleic Acids Research

February 2012; p ublished online October 2011 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 6763 words.

Transcriptional regulation plays a critical role in the life cycle of Mycobacterium smegmatis and its related species, M. tuberculosis, the causative microbe for tuberculosis. However, the...

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