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capsazepine

Overview page. Subjects: Medicine and Health.

A competitive antagonist of capsaicin.

See overview in Oxford Index

capsazepine

Overview page. Subjects: Medicine and Health.

A competitive antagonist of capsaicin.

See overview in Oxford Index

capsazepine

John Lackie.

in A Dictionary of Biomedicine

January 2010; p ublished online January 2010 .

Reference Entry. Subjects: Clinical Medicine. 6 words.

A competitive antagonist of *capsaicin.

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Effects of capsazepine, a transient receptor potential vanilloid type 1 antagonist, on morphine-induced antinociception, tolerance, and dependence in mice

T.-L. Nguyen, Y.-S. Nam, S.-Y. Lee, H.-C. Kim and C.-G. Jang.

in BJA: British Journal of Anaesthesia

November 2010; p ublished online August 2010 .

Journal Article. Subjects: Anaesthetics. 3546 words.

Background

Repeated morphine treatment has been shown to induce transient receptor potential vanilloid type 1 (TRPV1) expression in the spinal cord, dorsal...

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Capsaicin receptors mediate free radical-induced activation of cardiac afferent endings

Harold D Schultz and Elena E Ustinova.

in Cardiovascular Research

May 1998; p ublished online May 1998 .

Journal Article. Subjects: Cardiovascular Medicine. 4436 words.

Abstract

Objective: The effects of capsaicin on sensory neurons are mediated by its interaction with a specific membrane receptor and opening of...

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Ethanol dilates coronary arteries and increases coronary flow via transient receptor potential vanilloid 1 and calcitonin gene-related peptide

David Gazzieri, Marcello Trevisani, Francesca Tarantini, Paolo Bechi, Giulio Masotti, Gian Franco Gensini, Sergio Castellani, Niccolo' Marchionni, Pierangelo Geppetti and Selena Harrison.

in Cardiovascular Research

June 2006; p ublished online June 2006 .

Journal Article. Subjects: Cardiovascular Medicine. 5508 words.

Abstract

Objectives Consumption of alcoholic beverages reduces the risk of coronary artery disease (CAD), and epidemiological studies have shown...

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Characterization and comparison of recombinant human and rat TRPV1 receptors: effects of exo- and endocannabinoids<sup>†</sup>

P. M. W. Lam, J. McDonald and D. G. Lambert.

in BJA: British Journal of Anaesthesia

May 2005; p ublished online February 2005 .

Journal Article. Subjects: Anaesthetics. 4343 words.

Background. TRPV1 is a ligand-gated ion channel whose activation by capsaicin increases intracellular Ca2+ ([Ca2+]i). TRPV1 and cannabinoid CB1 receptor activation are capable...

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Role in Anxiety Behavior of the Endocannabinoid System in the Prefrontal Cortex

T. Rubino, N. Realini, C. Castiglioni, C. Guidali, D. Viganó, E. Marras, S. Petrosino, G. Perletti, M. Maccarrone, V. Di Marzo and D. Parolaro.

in Cerebral Cortex

June 2008; p ublished online October 2007 .

Journal Article. Subjects: Neuroscience. 6909 words.

In the present study we explored with a multidisciplinary approach, the role of anandamide (AEA) in the modulation of anxiety behavior at the level of the prefrontal cortex (PFC). Low doses...

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TRPV1 Receptors and Nasal Trigeminal Chemesthesis

Wayne L. Silver, Tod R. Clapp, Leslie M. Stone and Sue C. Kinnamon.

in Chemical Senses

November 2006; p ublished online August 2006 .

Journal Article. Subjects: Molecular and Cell Biology. 3087 words.

The trigeminal nerve responds to a wide variety of irritants. Trigeminal nerve fibers express several receptors that respond to chemicals, including TRPV1 (vanilloid) receptors,...

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Characteristics of propofol-evoked vascular pain in anaesthetized rats

R. Ando and C. Watanabe.

in BJA: British Journal of Anaesthesia

September 2005; p ublished online July 2005 .

Journal Article. Subjects: Anaesthetics. 4062 words.

Background. In this study we have assessed vascular pain caused by the i.v. anaesthetic agent, propofol, using the flexor reflex response and compared this with that of...

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Cardiac-specific knockout of ET<sub>A</sub> receptor mitigates low ambient temperature-induced cardiac hypertrophy and contractile dysfunction

Yingmei Zhang, Linlin Li, Yinan Hua, Jennifer M. Nunn, Feng Dong, Masashi Yanagisawa and Jun Ren.

in Journal of Molecular Cell Biology

April 2012; p ublished online April 2012 .

Journal Article. Subjects: Molecular and Cell Biology. 6993 words.

Cold exposure is associated with oxidative stress and cardiac dysfunction. The endothelin (ET) system, which plays a key role in myocardial homeostasis, may participate in cold...

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