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cardiotonic

Overview page. Subjects: Chemistry.

Having the effect of improving the tone of heart muscle. Cardiotonic steroids (cardiac glycosides) act directly on heart muscle to restore the power of the heart's contractions.

See overview in Oxford Index

cardiotonic

Edited by Richard Cammack, Teresa Atwood, Peter Campbell, Howard Parish, Anthony Smith, Frank Vella and John Stirling.

in Oxford Dictionary of Biochemistry and Molecular Biology

January 2006; p ublished online January 2008 .

Reference Entry. Subjects: Biochemistry. 29 words.

having the effect of improving the tone of heart muscle. Cardiotonic steroids (cardiac glycosides) act directly on heart

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cardiotonic

Overview page. Subjects: Chemistry.

Having the effect of improving the tone of heart muscle. Cardiotonic steroids (cardiac glycosides) act directly on heart muscle to restore the power of the heart's contractions.

See overview in Oxford Index

Endogenous cardiotonic steroids in chronic renal failure

Elena V. Kolmakova, Steven T. Haller, David J. Kennedy, Alina N. Isachkina, George V. Budny, Elena V. Frolova, Grzegorz Piecha, Elena R. Nikitina, Deepak Malhotra, Olga V. Fedorova, Joseph I. Shapiro and Alexei Y. Bagrov.

in Nephrology Dialysis Transplantation

September 2011; p ublished online February 2011 .

Journal Article. Subjects: Nephrology. 4283 words.

Background. Previous reports demonstrated that digitalis-like cardiotonic steroids (CTS) contribute to the pathogenesis of end-stage renal disease. The goal of the present...

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Cardiotonic drugs differentially alter cytosolic [Ca<sup>2+</sup>] to left ventricular relationships before and after ischemia in isolated guinea pig hearts

Qun Chen, Amadou K.S Camara, Samhita S Rhodes, Matthias L Riess, Enis Novalija and David F Stowe.

in Cardiovascular Research

October 2003; p ublished online October 2003 .

Journal Article. Subjects: Cardiovascular Medicine. 7070 words.

Abstract

Objective: Cardiotonic agents may differentially alter indices of the cytosolic [Ca2+]/left ventricular pressure (LVP) relationship...

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Role of endogenous cardiotonic steroids in sodium homeostasis

Wilhelm Schoner and Georgios Scheiner-Bobis.

in Nephrology Dialysis Transplantation

September 2008; p ublished online June 2008 .

Journal Article. Subjects: Nephrology. 4409 words.

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Preferential inhibition of I<sub>Kr</sub> by MCI-154, a putative cardiotonic Ca<sup>2+</sup> sensitizer, in guinea pig atrial cells

Koji Eto, Keitaro Hashimoto and Haruaki Nakaya.

in Cardiovascular Research

June 1998; p ublished online June 1998 .

Journal Article. Subjects: Cardiovascular Medicine. 6370 words.

Abstract

Objective: To define the electrophysiologic mechanism(s) by which MCI-154, a putative Ca2+ sensitizer, produces a positive inotropic...

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Gentiales

Edited by Michael Allaby.

in A Dictionary of Plant Sciences

March 2019; p ublished online March 2019 .

Reference Entry. Subjects: Plant Sciences and Forestry; Plant Physiology. 60 words.

A large order of plants, many of which produce *iridoid compounds, cardiotonic *glycosides, or indole *alkaloids; they have ...

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cardenolide

Edited by Richard Cammack, Teresa Atwood, Peter Campbell, Howard Parish, Anthony Smith, Frank Vella and John Stirling.

in Oxford Dictionary of Biochemistry and Molecular Biology

January 2006; p ublished online January 2008 .

Reference Entry. Subjects: Biochemistry. 35 words.

any of a group of C23 cardiotonic steroids characterized by a 14βhydroxyl group and an unsaturated γ‐lactone ring

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Back to the Future: Traditional Medicinals Revisited: The Use of Plants in Medicine

John W. Gruber and Ara DerMarderosian.

in Laboratory Medicine

February 1996; p ublished online December 2015 .

Journal Article. Subjects: Medical Skills; Pathology. 0 words.

Throughout history, plants have been used for medical purposes. In recent years, pharmacognosy (the study of medicinal and toxic products from natural sources) has reemerged. Many ancient...

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Monoclonal antibody against marinobufagenin reverses cardiac fibrosis in rats with chronic renal failure

Steven T. Haller, David J. Kennedy, Amjad Shidyak, George V. Budny, Deepak Malhotra, Olga V. Fedorova, Joseph I. Shapiro and Alexei Y. Bagrov.

in American Journal of Hypertension

June 2012; p ublished online June 2012 .

Journal Article. Subjects: Anatomy; Nephrology. 3991 words.

Background

Cardiotonic steroids (CTS) are implicated in pathophysiology of uremic cardiomyopathy. In the present study, we tested whether a monoclonal...

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Magnesium Sulfate Potentiates Effect of Digifab on Marinobufagenin-Induced Na/K-ATPase Inhibition

Irina E. Zazerskaya, Valentina V. Ishkaraeva, Elena V. Frolova, Nelly G. Solodovnikova, Yulia N. Grigorova, C. David Adair, Olga V. Fedorova and Alexei Y. Bagrov.

in American Journal of Hypertension

November 2013; p ublished online October 2013 .

Journal Article. Subjects: Cardiovascular Medicine; Biological Sciences. 2096 words.

BACKGROUND

Immunoneutralization of elevated circulating levels of endogenous digitalis-like Na/K-ATPase inhibitors (i.e. cardiotonic steroids (CTS))...

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Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone), isolated from <i>Plumbago zeylanica</i>, inhibits ultraviolet radiation-induced development of squamous cell carcinomas

Jordan M. Sand, Bilal Bin Hafeez, Mohammad Sarwar Jamal, Olya Witkowsky, Emily M. Siebers, Joseph Fischer and Ajit K. Verma.

in Carcinogenesis

January 2012; p ublished online November 2011 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 3893 words.

Plumbagin (PL) (5-hydroxy-2-methyl-1,4-napthoquinone), a medicinal plant-derived naphthoquinone, was isolated from the roots of the Plumbago zeylanica L. (also known as Chitrak). The roots...

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105RESULTS OF FONTAN OPERATION IN PATIENTS WITH ATRIOVENTRICULAR VALVE REGURGITATION

V.P. Podzolkov, M.R. Chiaureli, I.A. Yurlov, M.M. Zelenikin, D.V. Kovalev, V.I. Dontsova and S. Zaets.

in Interactive CardioVascular and Thoracic Surgery

October 2014; p ublished online October 2014 .

Journal Article. Subjects: Cardiovascular Medicine; Cardiothoracic Surgery. 0 words.

Objectives: The influence of concomitant atrioventricular valve regurgitation on results of Fontan operation remains disputable. The goal of this study was to compare early and late results...

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Na/K-ATPase/src complex mediates regulation of CD40 in renal parenchyma

Jeffrey X Xie, Shungang Zhang, Xiaoyu Cui, Jue Zhang, Hui Yu, Fatimah K Khalaf, Deepak Malhotra, David J Kennedy, Joseph I Shapiro, Jiang Tian and Steven T Haller.

in Nephrology Dialysis Transplantation

July 2018; p ublished online December 2017 .

Journal Article. Subjects: Nephrology. 7120 words.

ABSTRACT

Background

Recent studies have highlighted a critical role for CD40 in the pathogenesis of renal injury...

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Contractile and coronary vascular effects of pituitary adenylate cyclase activating polypeptide in neonatal pig hearts

Robert J. Ascuitto, Nancy T. Ross-Ascuitto, Alice E. Waddell and Phillip J. Kadowitz.

in Cardiovascular Research

February 1996 .

Journal Article. Subjects: Cardiovascular Medicine. 0 words.

Abstract

Objective

The purpose was to investigate the influence of the 38-amino-acid neuropeptide, pituitary adenylate...

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P444Therapeutic and prophylactic effects of oleuropein on ischemic and reperfusion injury of the heart in an in vivo and in vitro rat model

M Esmailidehaj, J Alihosaini, S Bajoovand and ME Rezvani.

in Cardiovascular Research

July 2014; p ublished online July 2014 .

Journal Article. Subjects: Cardiovascular Medicine. 0 words.

Purpose: Oleuropein is a very powerful phenolic antioxidant that exists in high concentrations in olive leaves. Several pharmacological benefits have been reported about...

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