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fenfluramine

Overview page. Subjects: Medicine and Health.

A serotonin reuptake inhibitor that also stimulates release of serotonin from the synaptosomes. Was used, in conjunction with phentermine, to treat obesity but has been withdrawn because of...

See overview in Oxford Index

fenfluramine

Michael Kent.

in Food and Fitness: A Dictionary of Diet and Exercise

January 1997; p ublished online January 2003 .

Reference Entry. Subjects: Cookery, Food, and Drink. 29 words.

An appetite suppressant, chemically related to amphetamine, but without its addictive properties. Fenfluramine is used in the treatment of obesity.

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fenfluramine

Michael Kent.

in Food and Fitness: A Dictionary of Diet and Exercise

P ublished online November 2016 .

Reference Entry. Subjects: Cookery, Food, and Drink. 30 words.

An appetite suppressant, chemically related to amphetamine, but without its addictive properties. Fenfluramine is used in the treatment of obesity.

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fenfluramine

Overview page. Subjects: Medicine and Health.

A serotonin reuptake inhibitor that also stimulates release of serotonin from the synaptosomes. Was used, in conjunction with phentermine, to treat obesity but has been withdrawn because of...

See overview in Oxford Index

fenfluramine

John Lackie.

in A Dictionary of Biomedicine

January 2010; p ublished online January 2010 .

Reference Entry. Subjects: Clinical Medicine. 37 words.

A serotonin reuptake inhibitor that also stimulates release of serotonin from the synaptosomes. Was used, in conjunction with phentermine, to

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fenfluramine

David A. Bender.

in A Dictionary of Food and Nutrition

January 2009; p ublished online January 2009 .

Reference Entry. Subjects: Cookery, Food, and Drink. 20 words.

Anorectic drug formerly used in the treatment of obesity, withdrawn in 1995 because of reports of heart valve damage.

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fenfluramine

David A. Bender.

in A Dictionary of Food and Nutrition

P ublished online January 2014 .

Reference Entry. Subjects: Cookery, Food, and Drink. 20 words.

Anorectic drug formerly used in the treatment of obesity, withdrawn in 1995 because of reports of heart valve damage.

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In Vitro Reaction of Formaldehyde with Fenfluramine: Conversion to <i>N</i>-Methyl Fenfluramine

Peter M. Gannett, Seble Hailu, Jonathan Daft, Devona James, Blanche Rybeck and Timothy S. Tracy.

in Journal of Analytical Toxicology

March 2001; p ublished online March 2001 .

Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 0 words.

Embalming is common, and it can create problems for the forensic scientist if a drug has been the cause death and this drug is also reactive toward the embalming fluid. Previous studies...

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d-Fenfluramine and animal models of eating disorders

B. Guardiola-Lemaitre.

in 5-Hydroxytryptamine in Psychiatry

February 1991; p ublished online March 2012 .

Chapter. Subjects: Neuroscience. 2417 words.

Pharmacological studies on food intake or body weight have traditionally used normal, young lean rats which are starved or fed a bland and balanced diet of laboratory chow, or rats that are...

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Prolactin response to d-fenfluramine in combat-related post-traumatic stress disorder

Isaac Schweitzer, Philip Morris, Malcolm Hopwood, Kay Maguire and Trevor Norman.

in International Journal of Neuropsychopharmacology

September 2004; p ublished online September 2004 .

Journal Article. 0 words.

Abstract

Central serotonergic function can be investigated by measuring the prolactin response to the serotonin releasing/uptake agent, d-fenfluramine. This...

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Evaluation of central serotonergic function in affective and related disorders by the fenfluramine challenge test: a critical review

Michael E. Newman, Baruch Shapira and Bernard Lerer.

in International Journal of Neuropsychopharmacology

July 1998; p ublished online July 1998 .

Journal Article. 0 words.

Abstract

Plasma prolactin levels following oral administration of the serotonin (5-HT) releasing agent, fenfluramine hydrochloride, have been extensively...

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Fenfluramine Reduces [<sup>11</sup>C]Cimbi-36 Binding to the 5-HT<sub>2A</sub> Receptor in the Nonhuman Primate Brain

Kai-Chun Yang, Vladimir Stepanov, Stefan Martinsson, Anders Ettrup, Akihiro Takano, Gitte M Knudsen, Christer Halldin, Lars Farde and Sjoerd J Finnema.

in International Journal of Neuropsychopharmacology

P ublished online June 2017 .

Journal Article. Subjects: Clinical Pharmacology and Therapeutics; Neurology; Psychiatry; Neuroscience. 5922 words.

Abstract

Background

[11C]Cimbi-36 is a serotonin 2A receptor agonist positron emission tomography radioligand that...

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d-Fenfluramine produces neuronal degeneration in localized regions of the cortex, thalamus, and cerebellum of the rat.

L Schmued, W Slikker, P Clausing and J Bowyer.

in Toxicological Sciences

March 1999; p ublished online March 1999 .

Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 0 words.

d-Fenfluramine is a potent serotonin (5-HT) reuptake inhibitor/releaser and, until its recent recall, was prescribed as an anoretic agent. This study demonstrates that 10 mg/kg...

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High prevalence of fenfluramine‐related aortic regurgitation in women with end‐stage renal disease secondary to Chinese herb nephropathy

Philippe Unger, Joëlle Nortier, Marie‐Carmen Muniz Martinez, Danièle Plein, Jean‐Luc Vandenbossche, Pierre Vereerstraeten and Jean‐Louis Vanherweghem.

in Nephrology Dialysis Transplantation

May 2003; p ublished online May 2003 .

Journal Article. Subjects: Nephrology. 3209 words.

Background. Non‐controlled studies have noted a high prevalence of valvular regurgitation in patients with Chinese herb nephropathy; most of these patients had taken appetite...

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Serotonin 5-HT<sub>2B</sub> receptor loss of function mutation in a patient with fenfluramine-associated primary pulmonary hypertension

Cédric Blanpain, Emmanuel Le Poul, Jasmine Parma, Christiane Knoop, Michel Detheux, Marc Parmentier, Gilbert Vassart and Marc J Abramowicz.

in Cardiovascular Research

December 2003; p ublished online December 2003 .

Journal Article. Subjects: Cardiovascular Medicine. 5536 words.

Abstract

Objective: Appetite-suppressant drug fenfluramine is implicated in primary pulmonary hypertension (PPH) but the molecular pathways that...

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fen-phen

David A. Bender.

in A Dictionary of Food and Nutrition

January 2009; p ublished online January 2009 .

Reference Entry. Subjects: Cookery, Food, and Drink. 28 words.

The combination of fenfluramine and phentermine, formerly used as an anorectic drug in the treatment of obesity; withdrawn in

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fen-phen

David A. Bender.

in A Dictionary of Food and Nutrition

P ublished online January 2014 .

Reference Entry. Subjects: Cookery, Food, and Drink. 45 words.

The combination of fenfluramine and phentermine, formerly used as an anorectic drug in the treatment of obesity; withdrawn in

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slimming pills

Michael Kent.

in Food and Fitness: A Dictionary of Diet and Exercise

January 1997; p ublished online January 2003 .

Reference Entry. Subjects: Cookery, Food, and Drink. 76 words.

Pills containing drugs to help weight reduction. They include appetite suppressants such as the stimulants diethylpropion and fenfluramine; thyroid extract

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appestat

Michael Kent.

in Food and Fitness: A Dictionary of Diet and Exercise

January 1997; p ublished online January 2003 .

Reference Entry. Subjects: Cookery, Food, and Drink. 31 words.

A hypothetical region of the brain thought to control the amount of food intake. Appetite suppressants, such as fenfluramine, probably

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slimming pills

Michael Kent.

in Food and Fitness: A Dictionary of Diet and Exercise

P ublished online November 2016 .

Reference Entry. Subjects: Cookery, Food, and Drink. 76 words.

Pills containing drugs to help weight reduction. They include appetite suppressants such as the stimulants diethylpropion and fenfluramine; thyroid extract

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fen-phen

Overview page. Subjects: Medicine and Health.

The combination of fenfluramine and phentermine, formerly used as an anorectic drug in the treatment of obesity; withdrawn in 1995 because of reports of heart valve damage.

See overview in Oxford Index