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hob

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A sprite or hobgoblin. In Middle English the word meant ‘country fellow’, and was a pet form of Rob, short for Robin or Robert, often referring specifically to Robin Goodfellow.

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From micrograms to picograms: quantitative PCR reduces the material demands of high-throughput sequencing

Matthias Meyer, Adrian W. Briggs, Tomislav Maricic, Barbara Höber, Barbara Höffner, Johannes Krause, Antje Weihmann, Svante Pääbo and Michael Hofreiter.

in Nucleic Acids Research

January 2008; p ublished online December 2007 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 3941 words.

Current efforts to recover the Neandertal and mammoth genomes by 454 DNA sequencing demonstrate the sensitivity of this technology. However, routine 454 sequencing applications still...

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Investigating affinity-maturation strategies and reproducibility of fluorescence-activated cell sorting using a recombinant ADAPT library displayed on staphylococci

Mikael Åstrand, Johan Nilvebrant, Mattias Björnmalm, Sarah Lindbo, Sophia Hober and John Löfblom.

in Protein Engineering, Design and Selection

May 2016; p ublished online March 2016 .

Journal Article. Subjects: Proteins. 6386 words.

During the past decades, advances in protein engineering have resulted in the development of various in vitro selection techniques (e.g. phage display) to facilitate discovery of new and...

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Increased Level of Interferon-<i>α</i> in Blood of Patients with Insulin-Dependent Diabetes Mellitus: Relationship with Coxsackievirus B Infection

Wassim Chehadeh, Jacques Weill, Marie-Christine Vantyghem, Gunar Alm, Jean Lefèbvre, Pierre Wattré and Didier Hober.

in The Journal of Infectious Diseases

June 2000; p ublished online June 2000 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 7470 words.

The activation of the interferon (IFN)-α system and its relationship with coxsackievirus B (CVB) infection has been analyzed in 56 patients with insulin-dependent diabetes mellitus (IDDM;...

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Charge engineering of a protein domain to allow efficient ion-exchange recovery

Torbjörn Gräslund, Gunnel Lundin, Mathias Uhlén, Per-Åke Nygren and Sophia Hober.

in Protein Engineering, Design and Selection

October 2000; p ublished online October 2000 .

Journal Article. Subjects: Proteins. 5581 words.

We have created protein domains with extreme surface charge. These mutated domains allow for ion-exchange chromatography under conditions favourable for selective and efficient capture,...

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Evaluation of different linker regions for multimerization and coupling chemistry for immobilization of a proteinaceous affinity ligand

Martin Linhult, Susanne Gülich, Torbjörn Gräslund, Per‐Åke Nygren and Sophia Hober.

in Protein Engineering, Design and Selection

December 2003; p ublished online December 2003 .

Journal Article. Subjects: Proteins. 3785 words.

Alkaline conditions are generally preferred for sanitization of chromatography media by cleaning‐in‐place (CIP) protocols in industrial biopharmaceutical processes. The use of such rigorous...

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Negatively charged purification tags for selective anion-exchange recovery

M. Hedhammar, T. Gräslund, M. Uhlén and S. Hober.

in Protein Engineering, Design and Selection

November 2004; p ublished online December 2004 .

Journal Article. Subjects: Proteins. 5236 words.

A novel strategy for the highly selective purification of recombinant fusion proteins using negatively charged protein domains, which were constructed by protein design, is described. A...

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Engineering streptococcal protein G for increased alkaline stability

Susanne Gülich, Martin Linhult, Stefan Ståhl and Sophia Hober.

in Protein Engineering, Design and Selection

October 2002; p ublished online October 2002 .

Journal Article. Subjects: Proteins. 6655 words.

Most protein-based affinity chromatography media are very sensitive towards alkaline treatment, which is a preferred method for regeneration and removal of contaminants from the...

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Antibody-Dependent Enhancement of Coxsackievirus B4 Infectivity of Human Peripheral Blood Mononuclear Cells Results in Increased Interferon-α Synthesis

Didier Hober, Wassim Chehadeh, Ahmed Bouzidi and Pierre Wattré.

in The Journal of Infectious Diseases

November 2001; p ublished online November 2001 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 8080 words.

IgG devoid of neutralizing activity and isolated from donor plasma by chromatography formed immune complexes with coxsackievirus B4 (CVB4) and significantly increased the infection of...

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Part II Substantive Issues, Ch.14 State Responsibility and Attribution

Kaj Hobér.

in The Oxford Handbook of International Investment Law

June 2008 .

Chapter. Subjects: Arbitration; Public International Law; International Law; Law. 35 pages. 17019 words.

This chapter presents an overview of the basic rules of attribution laid down in the ILC Articles. It provides a clear idea of the extent to which a state may be held responsible under...

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State Responsibility and Attribution

Kaj Hobér.

in The Oxford Handbook of International Investment Law

June 2008; p ublished online September 2012 .

Article. Subjects: Law; International Law. 17020 words.

This article deals with the rules of attribution and recent arbitral awards applying them. It gives a brief overview of the basic rules of attribution laid down in the International Law...

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