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Computer-assisted curation of a human regulatory core network from the biological literature

Philippe Thomas, Pawel Durek, Illés Solt, Bertram Klinger, Franziska Witzel, Pascal Schulthess, Yvonne Mayer, Domonkos Tikk, Nils Blüthgen and Ulf Leser.

in Bioinformatics

April 2015; p ublished online November 2014 .

Journal Article. Subjects: Bioinformatics and Computational Biology. 6091 words.

Motivation: A highly interlinked network of transcription factors (TFs) orchestrates the context-dependent expression of human genes. ChIP-chip experiments that interrogate the...

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Uniformly curated signaling pathways reveal tissue-specific cross-talks and support drug target discovery

Tamás Korcsmáros, Illés J. Farkas, Máté S. Szalay, Petra Rovó, Dávid Fazekas, Zoltán Spiró, Csaba Böde, Katalin Lenti, Tibor Vellai and Péter Csermely.

in Bioinformatics

August 2010; p ublished online June 2010 .

Journal Article. Subjects: Bioinformatics and Computational Biology. 6008 words.

Motivation: Signaling pathways control a large variety of cellular processes. However, currently, even within the same database signaling pathways are often curated at...

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The GNAT library for local and remote gene mention normalization

Jörg Hakenberg, Martin Gerner, Maximilian Haeussler, Illés Solt, Conrad Plake, Michael Schroeder, Graciela Gonzalez, Goran Nenadic and Casey M. Bergman.

in Bioinformatics

October 2011; p ublished online August 2011 .

Journal Article. Subjects: Bioinformatics and Computational Biology. 2378 words.

Summary: Identifying mentions of named entities, such as genes or diseases, and normalizing them to database identifiers have become an important step in many text and data...

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Low molecular weight heparin associated with spinal anaesthesia and gradual compression stockings in total hip replacement surgery. Arar Study Group.

C M Samama, F Clergue, J Barre, A Montefiore, P Ill and K Samii.

in BJA: British Journal of Anaesthesia

June 1997; p ublished online June 1997 .

Journal Article. Subjects: Anaesthetics. 0 words.

The benefit/risk ratio of administering heparin during spinal anaesthesia in patients undergoing total hip replacement (THR) has not been studied widely. We conducted a prospective,...

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Inhibiting poly(ADP-ribose) polymerase: a potential therapy against oligodendrocyte death

Sara Veto, Peter Acs, Jan Bauer, Hans Lassmann, Zoltan Berente, Gyorgy Setalo, Gabor Borgulya, Balazs Sumegi, Samuel Komoly, Ferenc Gallyas and Zsolt Illes.

in Brain

March 2010; p ublished online February 2010 .

Journal Article. Subjects: Neurology; Neuroscience. 7846 words.

Oligodendrocyte loss and demyelination are major pathological hallmarks of multiple sclerosis. In pattern III lesions, inflammation is minor in the early stages, and oligodendrocyte...

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Amyloid-dependent triosephosphate isomerase nitrotyrosination induces glycation and tau fibrillation

Francesc X. Guix, Gerard Ill-Raga, Ramona Bravo, Tadashi Nakaya, Gianni de Fabritiis, Mireia Coma, Gian Pietro Miscione, Jordi Villà-Freixa, Toshiharu Suzuki, Xavier Fernàndez-Busquets, Miguel A. Valverde, Bart de Strooper and Francisco J. Muñoz.

in Brain

May 2009; p ublished online February 2009 .

Journal Article. Subjects: Neurology; Neuroscience. 6758 words.

Alzheimer's disease neuropathology is characterized by neuronal death, amyloid β-peptide deposits and neurofibrillary tangles composed of paired helical filaments of tau protein. Although...

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Modulation of NMDA Receptor Current in Layer V Pyramidal Neurons of the Rat Prefrontal Cortex by P2Y Receptor Activation

Kerstin Wirkner, Albrecht Günther, Marco Weber, Segundo J. Guzman, Thomas Krause, Jochen Fuchs, Laszlo Köles, Wolfgang Nörenberg and Peter Illes.

in Cerebral Cortex

March 2007; p ublished online April 2006 .

Journal Article. Subjects: Neuroscience. 9058 words.

Current responses to N-methyl-D-aspartate (NMDA) in layer V pyramidal neurons of the rat prefrontal cortex were potentiated by the P2 receptor agonists adenosine 5′-triphosphate (ATP) and...

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Functional Regeneration of the ex-vivo Reconstructed Mesocorticolimbic Dopaminergic System

Elena Dossi, Claudia Heine, Ilenio Servettini, Francesca Gullo, Katja Sygnecka, Heike Franke, Peter Illes and Enzo Wanke.

in Cerebral Cortex

December 2013; p ublished online September 2012 .

Journal Article. Subjects: Neuroscience. 14833 words.

CNS reparative-medicine therapeutic strategies need answers on the putative recapitulation of the basic rules leading to mammalian CNS development. To achieve this aim, we focus on the...

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Rodent Cortical Astroglia Express In Situ Functional P2X<sub>7</sub> Receptors Sensing Pathologically High ATP Concentrations

João Filipe Oliveira, Thomas Riedel, Anna Leichsenring, Claudia Heine, Heike Franke, Ute Krügel, Wolfgang Nörenberg and Peter Illes.

in Cerebral Cortex

April 2011; p ublished online August 2010 .

Journal Article. Subjects: Neuroscience. 10014 words.

ATP is an important neuronal and astroglial signaling molecule in the brain. In the present study, brain slices were prepared from the prefrontal cortex (PFC) of Wistar rats and 2 lines of...

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Genotyping-by-sequencing map permits identification of clubroot resistance QTLs and revision of the reference genome assembly in cabbage (<i>Brassica oleracea</i> L.)

Jonghoon Lee, Nur Kholilatul Izzah, Beom-Soon Choi, Ho Jun Joh, Sang-Choon Lee, Sampath Perumal, Joodeok Seo, Kyounggu Ahn, Eun Ju Jo, Gyung Ja Choi, Ill-Sup Nou, Yeisoo Yu and Tae-Jin Yang.

in DNA Research

February 2016; p ublished online November 2015 .

Journal Article. Subjects: Molecular Biology and Genetics; Genetics and Genomics. 8218 words.

Clubroot is a devastating disease caused by Plasmodiophora brassicae and results in severe losses of yield and quality in Brassica crops. Many clubroot resistance genes and markers are...

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