Oxford Index Search Results

You are looking at 1-10 of 2,026 items for:

knock-in x clear all

Refine by subject

 

Refine by type

Refine by product

 

knock-in

Overview page. Subjects: Economics.

Two types of barrier option which become activated if the underlying moves through a trigger price or rate in the case of the knock-in, or deactivated in the case of ...

See overview in Oxford Index

knock-in

Overview page. Subjects: Economics.

Two types of barrier option which become activated if the underlying moves through a trigger price or rate in the case of the knock-in, or deactivated in the case of ...

See overview in Oxford Index

Rapid conditional knock-down–knock-in system for mammalian cells

Michael Hölzel, Michaela Rohrmoser, Mathias Orban, Cornelia Hömig, Thomas Harasim, Anastassia Malamoussi, Anita Gruber-Eber, Vigo Heissmeyer, Georg Bornkamm and Dirk Eick.

in Nucleic Acids Research

February 2007; p ublished online December 2006 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 4165 words.

RNA interference (RNAi) is a powerful tool to analyze gene function in mammalian cells. However, the interpretation of RNAi knock-down phenotypes can be hampered by off-target effects or...

Go to Oxford Journals »  home page

knock-in

John Lackie.

in A Dictionary of Biomedicine

January 2010; p ublished online January 2010 .

Reference Entry. Subjects: Clinical Medicine. 17 words.

A transgenic animal to which a new gene has been added rather than eliminated (knocked out).

Go to Oxford Reference »  home page

Lysosomal dysfunction causes neurodegeneration in mucolipidosis II ‘knock-in’ mice

K. Kollmann, M. Damme, S. Markmann, W. Morelle, M. Schweizer, I. Hermans-Borgmeyer, A. K. Röchert, S. Pohl, T. Lübke, J.-C. Michalski, R. Käkelä, S. U. Walkley and T. Braulke.

in Brain

September 2012; p ublished online August 2012 .

Journal Article. Subjects: Neurology; Neuroscience. 7065 words.

Mucolipidosis II is a neurometabolic lysosomal trafficking disorder of infancy caused by loss of mannose 6-phosphate targeting signals on lysosomal proteins, leading to lysosomal...

Go to Oxford Journals »  home page

Early autophagic response in a novel knock-in model of Huntington disease

Mary Y. Heng, Duy K. Duong, Roger L. Albin, Sara J. Tallaksen-Greene, Jesse M. Hunter, Mathieu J. Lesort, Alex Osmand, Henry L. Paulson and Peter J. Detloff.

in Human Molecular Genetics

October 2010; p ublished online July 2010 .

Journal Article. Subjects: Genetics and Genomics. 10222 words.

The aggregation of mutant polyglutamine (polyQ) proteins has sparked interest in the role of protein quality-control pathways in Huntington's disease (HD) and related polyQ disorders....

Go to Oxford Journals »  abstract

Altered cholesterol metabolism in human apolipoprotein E4 knock-in mice

Hiroki Hamanaka, Yuko Katoh-Fukui, Kazuo Suzuki, Mariko Kobayashi, Rika Suzuki, Yoshiko Motegi, Yoko Nakahara, Aya Takeshita, Mizue Kawai, Koichi Ishiguro, Minesuke Yokoyama and Shinobu C. Fujita.

in Human Molecular Genetics

February 2000; p ublished online February 2000 .

Journal Article. Subjects: Genetics and Genomics. 7657 words.

The ε 4 allele of apolipoprotein E (apoE) is associated with an increased risk of developing Alzheimer’s disease (AD). To accurately determine the...

Go to Oxford Journals »  abstract

Neurological abnormalities in a knock-in mouse model of Huntington’s disease

Chin-Hsing Lin, Sara Tallaksen-Greene, Wei-Ming Chien, Jamie A. Cearley, Walker S. Jackson, Andrew B. Crouse, Songrong Ren, Xiao-Jiang Li, Roger L. Albin and Peter J. Detloff.

in Human Molecular Genetics

January 2001; p ublished online January 2001 .

Journal Article. Subjects: Genetics and Genomics. 6387 words.

Mice representing precise genetic replicas of Huntington’s disease (HD) were made using gene targeting to replace the short CAG repeat of the mouse Huntington’s disease gene homolog (Hdh)...

Go to Oxford Journals »  abstract

Length-Dependent Gametic CAG Repeat Instability in the Huntington's Disease Knock-in Mouse

Vanessa C. Wheeler, Wojtek Auerbach, Jacqueline K. White, Jayalakshmi Srinidhi, Anna Auerbach, Angela Ryan, Mabel P. Duyao, Vladimir Vrbanac, Meredith Weaver, James F. Gusella, Alexandra L. Joyner and Marcy E. MacDonald.

in Human Molecular Genetics

January 1999; p ublished online January 1999 .

Journal Article. Subjects: Genetics and Genomics. 7442 words.

The CAG repeats in the human Huntington's disease (HD) gene exhibit striking length-dependent intergenerational instability, typically small size increases or decreases of one to a few...

Go to Oxford Journals »  home page

Knock-on processes in superfluid vortex avalanches and pulsar glitch statistics

L. Warszawski and A. Melatos.

in Monthly Notices of the Royal Astronomical Society

January 2013; p ublished online November 2012 .

Journal Article. Subjects: Astronomy and Astrophysics. 11752 words.

A framework is presented for a statistical theory of neutron star glitches, motivated by the results emerging from recent Gross–Pitaevskii simulations of pinned, decelerating quantum...

Go to Oxford Journals »  abstract

Improved Health and Living in a “Perpetually Half Knocked-Up Condition”

Ralph Colp Jr. M.D..

in Darwin's Illness

June 2008; p ublished online September 2011 .

Chapter. Subjects: History of Science and Technology. 3677 words.

In the nine years from 1872 to 1881, the main events in Charles Darwin's health were several acute illnesses, persistent chronic illness, emotional upsets from work and certain social...

Go to University Press of Florida »  abstract