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matrilysin

Overview page. Subjects: Chemistry.

A matrix metallopeptidases (MMP-7, EC 3.4.24.23, 267 aa) involved in tissue remodelling and in the cellular invasion of tissues. Matrilysin-2 is MMP-26.

See overview in Oxford Index

matrilysin

John Lackie.

in A Dictionary of Biomedicine

January 2010; p ublished online January 2010 .

Reference Entry. Subjects: Clinical Medicine. 23 words.

A matrix metallopeptidases (MMP-7, EC 3.4.24.23, 267 aa) involved in tissue remodelling and in the cellular invasion of tissues. Matrilysin-2

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matrilysin

Overview page. Subjects: Chemistry.

A matrix metallopeptidases (MMP-7, EC 3.4.24.23, 267 aa) involved in tissue remodelling and in the cellular invasion of tissues. Matrilysin-2 is MMP-26.

See overview in Oxford Index

matrilysin

Edited by Richard Cammack, Teresa Atwood, Peter Campbell, Howard Parish, Anthony Smith, Frank Vella and John Stirling.

in Oxford Dictionary of Biochemistry and Molecular Biology

January 2006; p ublished online January 2008 .

Reference Entry. Subjects: Biochemistry. 81 words.

EC 3.4.24.23; other names: matrin; uterine metalloendopeptidase; matrix metalloproteinase 7 (abbr.: MMP7); putative (or punctuated) metalloproteinase‐1 (

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Interactions of Human Matrix Metalloproteinase 7 (Matrilysin) with the Inhibitors Thiorphan and R-94138

Hiroshi Oneda and Kuniyo Inouye.

in The Journal of Biochemistry

March 2001; p ublished online March 2001 .

Journal Article. Subjects: Biochemistry. 0 words.

The effects of the metalloproteinase inhibitors thiorphan and R-94138 on the matrilysincatalyzed hydrolysis of (7-methoxycoumarin-4-yl)acetyl-L-Pro-L-Leu-Gly-L-Leu-[N 3-(2,4-...

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Inhibitory Effects of Green Tea Catechins on the Activity of Human Matrix Metalloproteinase 7 (Matrilysin)

Hiroshi Oneda, Misa Shiihara and Kuniyo Inouye.

in The Journal of Biochemistry

May 2003; p ublished online May 2003 .

Journal Article. Subjects: Biochemistry. 4493 words.

Inhibitory effects of green tea catechins and their derivatives on the matrilysin-catalyzed hydrolysis of a synthetic substrate, (7-methoxycoumarin-4-yl)acetyl-l-Pro-l-Leu-Gly-l-Leu-[Nnull...

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Sulindac treatment alters collagen and matrilysin expression in adenomas of <i>Apc<sup>Min/+</sup> </i> mice

Hector Guillen-Ahlers, Steven A. Buechler, Mark A. Suckow, Francis J. Castellino and Victoria A. Ploplis.

in Carcinogenesis

July 2008; p ublished online May 2008 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 4558 words.

Non-steroidal anti-inflammatory drugs (NSAIDs) have shown potential as chemopreventive agents against cancer formation, especially colorectal cancers. However, the mechanisms by which these...

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Association of matrilysin-2 (MMP-26) expression with tumor progression and activation of MMP-9 in esophageal squamous cell carcinoma

Hiroyuki Yamamoto, Akravit Vinitketkumnuen, Yasushi Adachi, Hiroaki Taniguchi, Tamaki Hirata, Nobuki Miyamoto, Katsuhiko Nosho, Arisa Imsumran, Masahiro Fujita, Masao Hosokawa, Yuji Hinoda and Kohzoh Imai.

in Carcinogenesis

December 2004; p ublished online December 2004 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 4845 words.

Expression of matrilysin-2, matrix metalloproteinase (MMP)-26, has been implicated in the progression of several types of human cancer. Matrilysin-2 has been reported to be a physiological...

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Association of matrilysin mRNA expression with K-<i>ras</i> mutations and progression in pancreatic ductal adenocarcinomas

Hiroshi Fukushima, Hiroyuki Yamamoto, Fumio Itoh, Hideaki Nakamura, Yongfen Min, Shina Horiuchi, Shouhei Iku, Shigeru Sasaki and Kohzoh Imai.

in Carcinogenesis

July 2001; p ublished online July 2001 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 3370 words.

The matrix metalloproteinase matrilysin has been implicated in the progression of gastrointestinal and other cancers. The aim of this study was to examine matrilysin mRNA expression and...

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Refolding and Recovery of Recombinant Human Matrix Metalloproteinase 7 (Matrilysin) from Inclusion Bodies Expressed by <i>Escherichia coli</i>

Hiroshi Oneda and Kunlyo Inouye.

in The Journal of Biochemistry

November 1999; p ublished online November 1999 .

Journal Article. Subjects: Biochemistry. 0 words.

The recombinant prepro-fonn of human matrix metalloproteinase 7 (matrilysin or MMP-7) was overexpressed in Escherichia coli as insoluble inclusion bodies. The recombinant protein was...

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Insulin-like growth factor-I receptor blockade reduces the invasiveness of gastrointestinal cancers via blocking production of matrilysin

Yasushi Adachi, Rong Li, Hiroyuki Yamamoto, Yongfen Min, Wenhua Piao, Yu Wang, Arisa Imsumran, Hua Li, Yoshiaki Arimura, Choon-Taek Lee, Kohzoh Imai, David P. Carbone and Yasuhisa Shinomura.

in Carcinogenesis

August 2009; p ublished online June 2009 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 5267 words.

Insulin-like growth factor-I receptor (IGF-IR) signaling is required for carcinogenicity and proliferation of gastrointestinal (GI) cancers. We have previously shown significant therapeutic...

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