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Identification of the CIMP-like subtype and aberrant methylation of members of the chromosomal segregation and spindle assembly pathways in esophageal adenocarcinoma

Lutz Krause, Katia Nones, Kelly A. Loffler, Derek Nancarrow, Harald Oey, Yue Hang Tang, Nicola J. Wayte, Ann Marie Patch, Kalpana Patel, Sandra Brosda, Suzanne Manning, Guy Lampe, Andrew Clouston, Janine Thomas, Jens Stoye, Damian J. Hussey, David I. Watson, Reginald V. Lord, Wayne A. Phillips, David Gotley, B.Mark Smithers, David C. Whiteman, Nicholas K. Hayward, Sean M. Grimmond, Nicola Waddell and Andrew P. Barbour.

in Carcinogenesis

April 2016; p ublished online February 2016 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 6533 words.

The incidence of esophageal adenocarcinoma (EAC) has risen significantly over recent decades. Although survival has improved, cure rates remain poor, with <20% of patients surviving 5...

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Penetrance for copy number variants associated with schizophrenia

Evangelos Vassos, David A. Collier, Simon Holden, Christine Patch, Dan Rujescu, David St Clair and Cathryn M. Lewis.

in Human Molecular Genetics

September 2010; p ublished online June 2010 .

Journal Article. Subjects: Genetics and Genomics. 3136 words.

The discovery of ‘high-risk’ de novo copy number variants (CNVs) associated with neuropsychiatric disorders such as schizophrenia offers the opportunity to translate these findings into...

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Benzothioxalone derivatives as novel inhibitors of UDP-<i>N</i>-acetylglucosamine enolpyruvyl transferases (MurA and MurZ)

Keith Miller, Colin J. Dunsmore, Jennifer A. Leeds, Simon G. Patching, Meena Sachdeva, Katy L. Blake, William J. Stubbings, Katie J. Simmons, Peter J. F. Henderson, Joe De Los Angeles, Colin W. G. Fishwick and Ian Chopra.

in Journal of Antimicrobial Chemotherapy

December 2010; p ublished online September 2010 .

Journal Article. Subjects: Medical Oncology; Critical Care. 3662 words.


We sought to identify and characterize new inhibitors of MurA and MurZ, which are enzymes involved in the early stages of bacterial peptidoglycan...

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Piperacillin–tazobactam versus ciprofloxacin plus amoxicillin in the treatment of infective episodes after liver transplantation

John Philpott-Howard, Andrew Burroughs, Neil Fisher, Mark Hastings, Christopher Kibbler, David Mutimer, David Patch, Nancy Rolando, Jim Wade, Julia Wendon and John O’Grady.

in Journal of Antimicrobial Chemotherapy

December 2003; p ublished online December 2003 .

Journal Article. Subjects: Medical Oncology; Critical Care. 5270 words.

An optimum antimicrobial regimen for bacterial infection after orthotopic liver transplantation has not been identified. In this prospective 4 year study of patients undergoing liver...

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Brief Report: A Qualitative Analysis of Discussions about HIV in Families of Parents with HIV

Rosalie Corona, Burton O. Cowgill, Laura M. Bogart, Michelle T. Parra, Gery Ryan, Marc N. Elliott, Susan K. Park, Jennifer Patch and Mark A. Schuster.

in Journal of Pediatric Psychology

July 2009; p ublished online November 2008 .

Journal Article. Subjects: Child and Adolescent Psychiatry; Psychology. 2330 words.

Objective To explore communication about HIV prevention, risk behaviors, and transmission in families affected by HIV. Methods Semi-structured interviews were conducted with 33...

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Assessment of reproducibility of creatinine measurement and MELD scoring in four liver transplant units in the UK

Carol Goulding, Evangelous Cholongitas, Devi Nair, Andrew Kerry, David Patch, Murat Akyol, Simon Walker, Derek Manas, David Mc Clure, Liesl Smith, Neville Jamieson, Ingela Oberg, David Cartwright and Andrew K. Burroughs.

in Nephrology Dialysis Transplantation

March 2010; p ublished online November 2009 .

Journal Article. Subjects: Nephrology. 4179 words.

The Model for End-Stage Liver Disease (MELD) or similar scoring system is proposed in the UK for prioritization for liver transplantation. We evaluated the reproducibility of creatinine...

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Predicting the success of primer extension genotyping assays using statistical modeling

Anton Yuryev, JianPing Huang, Mark Pohl, Robert Patch, Felicia Watson, Peter Bell, Miriam Donaldson, Michael S. Phillips and Michael T. Boyce‐Jacino.

in Nucleic Acids Research

December 2002; p ublished online December 2002 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 7525 words.

Using an empirical panel of more than 20 000 single base primer extension (SNP‐IT) assays we have developed a set of statistical scores for evaluating and rank ordering various parameters of...

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A decision analysis model for diagnostic strategies using DNA testing for hereditary haemochromatosis in at risk populations

K. Cooper, J. Bryant, J. Picot, A. Clegg, P.R. Roderick, W.M. Rosenberg and C. Patch.

in QJM: An International Journal of Medicine

August 2008; p ublished online June 2008 .

Journal Article. Subjects: Medicine and Health. 5249 words.

Background: New techniques for diagnosing hereditary haemochromatosis (HHC) have become available alongside traditional tests such as liver biopsy and serum iron studies.


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Can motivational signs prompt increases in incidental physical activity in an Australian health-care facility?

A. L. Marshall, A. E. Bauman, C. Patch, J. Wilson and J. Chen.

in Health Education Research

December 2002; p ublished online December 2002 .

Journal Article. Subjects: Public Health and Epidemiology. 3418 words.

This study aimed to evaluate whether a stair-promoting signed intervention could increase the use of the stairs over the elevator in a health-care facility. A time-series design was...

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American Indian Economies

Michael E. Smith, Terence N. D'Altroy, José Luis de Rojas, Robert Patch and David M. Wishart.

in The Oxford Encyclopedia of Economic History

January 2003; p ublished online January 2005 .

Reference Entry. Subjects: Economic History. 10039 words.

This entry contains five subentries, an overview and discussions of Inca, Aztec, Maya, and indigenous North American

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