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pokeweed mitogen

Overview page. Subjects: Chemistry.

A lectin (q.v.) extracted from rhizomes of the pokeweed, Phytolocca americana, that stimulates the proliferation of lymphocytes, particularly mouse T and B lymphocytes.

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pokeweed mitogen

Overview page. Subjects: Chemistry.

A lectin (q.v.) extracted from rhizomes of the pokeweed, Phytolocca americana, that stimulates the proliferation of lymphocytes, particularly mouse T and B lymphocytes.

See overview in Oxford Index

pokeweed mitogen

John Lackie.

in A Dictionary of Biomedicine

January 2010; p ublished online January 2010 .

Reference Entry. Subjects: Clinical Medicine. 21 words.

Any of the *lectins from Phytolacca americana (pokeweed), all of which are mitogenic for T cells. They bind β-

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pokeweed mitogen

Robert C. King, William D. Stansfield and Pamela K. Mulligan.

in A Dictionary of Genetics

January 2007; p ublished online January 2007 .

Reference Entry. Subjects: Genetics and Genomics. 25 words.

a lectin (q.v.) extracted from rhizomes of the pokeweed, Phytolocca americana, that stimulates the proliferation of lymphocytes, particularly

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pokeweed mitogen

Robert C. King, Pamela K. Mulligan and William D. Stansfield.

in A Dictionary of Genetics

January 2013; p ublished online January 2014 .

Reference Entry. Subjects: Genetics and Genomics. 25 words.

a lectin (q.v.) extracted from rhizomes of the pokeweed, Phytolacca americana, that stimulates the proliferation of lymphocytes,

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pokeweed mitogen

Edited by Richard Cammack, Teresa Atwood, Peter Campbell, Howard Parish, Anthony Smith, Frank Vella and John Stirling.

in Oxford Dictionary of Biochemistry and Molecular Biology

January 2006; p ublished online January 2008 .

Reference Entry. Subjects: Biochemistry. 76 words.

abbr.: PWM; a plant lectin (phytoagglutinin) extractable from the roots of pokeweed, Phytolacca americana, a North American plant.

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PWM

Edited by Richard Cammack, Teresa Atwood, Peter Campbell, Howard Parish, Anthony Smith, Frank Vella and John Stirling.

in Oxford Dictionary of Biochemistry and Molecular Biology

January 2006; p ublished online January 2008 .

Reference Entry. Subjects: Biochemistry. 5 words.

abbr. for pokeweed mitogen.

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concanavalin A

Overview page. Subjects: Chemistry.

A lectin (q.v.) derived from Canavalia ensiformis, the jack bean; abbreviated conA. The compound stimulates T lymphocytes to enter mitosis. Compare with pokeweed mitogen.

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Suppression of mitogen-induced lymphocyte proliferation by syringomycin-E

Vijendra K. Singh and Jon Y. Takemoto.

in FEMS Immunology & Medical Microbiology

September 1996; p ublished online January 2006 .

Journal Article. 0 words.

Abstract

Syringomycin E (SR-E) is low molecular weight bacterial lipodepsipeptide with antifungal properties. Owing to immunosuppressive activities of such...

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Recurrences of Cytomegalovirus Retinitis in a Human Immunodeficiency Virus-Infected Patient, Despite Potent Antiretroviral Therapy and Apparent Immune Reconstitution

Steven C. Johnson, Constance A. Benson, David W. Johnson and Adriana Weinberg.

in Clinical Infectious Diseases

March 2001; p ublished online March 2001 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 2871 words.

We describe a 42-year-old man with human immunodeficiency virus infection who developed multiple recurrences of cytomegalovirus (CMV) retinitis despite receiving highly active...

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Modulation of lymphocyte proliferative responses by a canine Lyme disease vaccine of recombinant outer surface protein A (OspA)

J.W. Chiao, P. Villalon, Ira Schwartz and Gary P. Wormser.

in FEMS Immunology & Medical Microbiology

July 2000; p ublished online September 2006 .

Journal Article. Subjects: Medical Microbiology and Virology; Biotechnology; Genetics and Genomics; Microbiology; Molecular and Cell Biology. 2103 words.

Abstract

The modulation of human lymphocyte proliferative responses was demonstrated with a recombinant outer surface protein A (OspA) vaccine preparation...

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Psoriasis patients have T-cells with reduced responsiveness to common mycobacterial antigens

Maria-Luisa Bay, Amira Lehrer, Amalia Bressanelli, Julio Morini, Oscar Bottasso and John Stanford.

in FEMS Immunology & Medical Microbiology

May 1998; p ublished online January 2006 .

Journal Article. 2712 words.

Abstract

Heparinised blood samples were obtained from 20 patients with chronic plaque psoriasis and from 13 age-matched healthy controls. After preliminary...

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Reduced Immune Responses in Rhesus Monkeys Subjected to Dietary Restriction

Ellen B. Roecker, Joseph W. Kemnitz, William B. Ershler and Richard Weindruch.

in The Journals of Gerontology: Series A

July 1996 .

Journal Article. Subjects: Geriatric Medicine; Biological Sciences. 0 words.

Dietary restriction (DR) has emerged as a major paradigm in experimental gerontology. The effects of DR on rodents are numerous and include reduced rates of immunologic aging, delayed...

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Evidence for Viral Persistence in Patients Who Test Positive for Anti-Hepatitis C Virus Antibodies and Have Normal Alanine Aminotransferase Levels

Marek Radkowski, Andrzej Horban, Juan F. Gallegos-Orozco, Agnieszka Pawelczyk, Joanna Jablonska, Jeffrey Wilkinson, Debra Adair and Tomasz Laskus.

in The Journal of Infectious Diseases

May 2005; p ublished online May 2005 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 2870 words.

It is unclear whether patients who test positive for anti-hepatitis C virus (HCV) antibodies and have normal alanine aminotransferase (ALT) levels remain infected with the virus. Eleven...

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Comparing seven mitogens with PHA-M for improved lymphocyte stimulation in dicentric chromosome analysis for biodosimetry

C. Beinke, M. Port, A. Lamkowski and M. Abend.

in Radiation Protection Dosimetry

February 2016; p ublished online May 2015 .

Journal Article. Subjects: Nuclear Chemistry, Photochemistry, and Radiation. 3281 words.

Dicentric chromosome analysis (DCA) is the gold standard for individual radiation dose estimation. Two limiting factors of DCA are the time-consuming lymphocyte stimulation and...

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Viral and Immunologic Examination of Human Immunodeficiency Virus Type 1—Infected, Persistently Seronegative Persons

Dennis L. Ellenberger, Patrick S. Sullivan, Jonathan Dorn, Charles Schable, Thomas J. Spira, Thomas M. Folks and Renu B. Lal.

in The Journal of Infectious Diseases

October 1999; p ublished online October 1999 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 5537 words.

Persons who were human immunodeficiency virus type 1 (HIV-1)-infected but who remained persistently seronegative (HIPS) on HIV-1 antibody tests were examined through AIDS case surveillance....

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Cluster analysis on the lectin binding patterns of marine microalgae

Eun Seob Cho.

in Journal of Plankton Research

March 2003; p ublished online March 2003 .

Journal Article. Subjects: Marine and Estuarine Biology; Zoology and Animal Sciences. 2910 words.

Fluorescent lectin binding patterns constructed using the Dollop parsimony method were analyzed to study the relationship of Gymnodiniales, the genus Prorocentrum, the genus Alexandrium and...

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Thoracic epidural analgesia inhibits the neuro-hormonal but not the acute inflammatory stress response after radical retropubic prostatectomy

F. Fant, E. Tina, D. Sandblom, S.-O. Andersson, A. Magnuson, E. Hultgren-Hörnkvist, K. Axelsson and A. Gupta.

Edited by L. Colvin.

in BJA: British Journal of Anaesthesia

May 2013; p ublished online January 2013 .

Journal Article. Subjects: Anaesthetics. 4628 words.

Background

Epidural anaesthesia and analgesia has been shown to suppress the neuro-hormonal stress response, but its role in the inflammatory response is...

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Spontaneous production of anti‐IFN‐α and anti‐IL‐12 autoantibodies by thymoma cells from myasthenia gravis patients suggests autoimmunization in the tumor

Hiroyuki Shiono, Yat Lei Wong, Ian Matthews, Jian‐Li Liu, Wei Zhang, Gary Sims, Anthony Meager, David Beeson, Angela Vincent and Nicholas Willcox.

in International Immunology

August 2003; p ublished online August 2003 .

Journal Article. Subjects: Immunology; Biological Sciences. 7209 words.

Myasthenia gravis (MG) is mediated by autoantibodies to the acetylcholine receptor (AChR), expressed in muscle and rare thymic myoid cells. Most early‐onset cases show thymic lymph...

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Inhibitory action of sulfatide, a putative ligand for L-selectin, on B cell proliferation and Ig production

Akihiro Konno, Koji Nunogami, Taizo Wada, Akihiro Yachie, Yasuo Suzuki, Nobutaka Takahashi, Takashi Suzuki, Daisei Miyamoto, Makoto Kiso, Akira Hasegawa and Toshio Miyawaki.

in International Immunology

December 1996 .

Journal Article. Subjects: Immunology; Biological Sciences. 0 words.

The interaction of L-selectin and its ligand is widely accepted to mediate leukocyte rolling and adhesion on the endothelial surface. Although L-selectin is ubiquitously expressed on...

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Roles of PU.1 in monocyte- and mast cell-specific gene regulation: PU.1 transactivates CIITA pIV in cooperation with IFN-γ

Tomonobu Ito, Chiharu Nishiyama, Nobuhiro Nakano, Makoto Nishiyama, Yoshihiko Usui, Kazuyoshi Takeda, Shunsuke Kanada, Kanako Fukuyama, Hisaya Akiba, Tomoko Tokura, Mutsuko Hara, Ryoji Tsuboi, Hideoki Ogawa and Ko Okumura.

in International Immunology

July 2009; p ublished online June 2009 .

Journal Article. Subjects: Biological Sciences; Immunology. 6476 words.

Over-expression of PU.1, a myeloid- and lymphoid-specific transcription factor belonging to the Ets family, induces monocyte-specific gene expression in mast cells. However, the effects of...

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