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semaphorin

Overview page. Subjects: Chemistry.

One of a class of proteins that act as guidance molecules during the development of nerve cells, immune cells, blood vessels, bone, and other tissues. There are several classes, some...

See overview in Oxford Index

semaphorin

Overview page. Subjects: Chemistry.

One of a class of proteins that act as guidance molecules during the development of nerve cells, immune cells, blood vessels, bone, and other tissues. There are several classes, some...

See overview in Oxford Index

semaphorin

Elizabeth Martin and Robert Hine.

in A Dictionary of Biology

January 2008; p ublished online January 2008 .

Reference Entry. Subjects: Biological Sciences. 124 words.

One of a class of proteins that act as guidance molecules during the development of nerve cells, immune cells, blood

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semaphorin

Edited by Robert Hine and Elizabeth Martin.

in A Dictionary of Biology

June 2016; p ublished online September 2015 .

Reference Entry. Subjects: Biological Sciences. 124 words.

One of a class of proteins that act as guidance molecules during the development of nerve cells, immune cells, blood

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semaphorins

John Lackie.

in A Dictionary of Biomedicine

January 2010; p ublished online January 2010 .

Reference Entry. Subjects: Clinical Medicine. 58 words.

A conserved family of proteins that inhibit the movement of the *nerve growth cone and influence the architecture of

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semaphorin

Edited by Richard Cammack, Teresa Atwood, Peter Campbell, Howard Parish, Anthony Smith, Frank Vella and John Stirling.

in Oxford Dictionary of Biochemistry and Molecular Biology

January 2006; p ublished online January 2008 .

Reference Entry. Subjects: Biochemistry. 96 words.

any of a family of secreted or membrane‐bound proteins (≈750 residues) that are expressed in various embryonal and adult tissues.

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Semaphorin 5B Is a Novel Inhibitory Cue for Corticofugal Axons

Robyn L. M. Lett, Wenyan Wang and Timothy P. O'Connor.

in Cerebral Cortex

June 2009; p ublished online October 2008 .

Journal Article. Subjects: Neuroscience. 9778 words.

Neuronal connectivity is generated by the precise guidance of neuronal growth cones in response to the spatiotemporal distribution of molecular guidance cues in the developing embryo. Here...

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Integration of Opposing Semaphorin Guidance Cues in Cortical Axons

Tina Ruediger, Geraldine Zimmer, Sandra Barchmann, Valérie Castellani, Dominique Bagnard and Jürgen Bolz.

in Cerebral Cortex

March 2013; p ublished online February 2012 .

Journal Article. Subjects: Neuroscience. 8153 words.

Previous work demonstrated that members of the semaphorin family, Sema3A and Sema3C, act as repulsive and attractive guidance signals, respectively, for cortical axons. During the...

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Class 3 semaphorins influence oligodendrocyte precursor recruitment and remyelination in adult central nervous system

Gabrièle Piaton, Marie-Stéphane Aigrot, Anna Williams, Sarah Moyon, Vanja Tepavcevic, Imane Moutkine, Julien Gras, Katherine S. Matho, Alain Schmitt, Heidi Soellner, Andrea B. Huber, Philippe Ravassard and Catherine Lubetzki.

in Brain

April 2011; p ublished online March 2011 .

Journal Article. Subjects: Neurology; Neuroscience. 7166 words.

Oligodendrocyte precursor cells, which persist in the adult central nervous system, are the main source of central nervous system remyelinating cells. In multiple sclerosis, some...

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Class 3 semaphorins modulate the invasive capacity of rheumatoid arthritis fibroblast-like synoviocytes

Man Wai Tang, Beatriz Malvar Fernández, Simon P Newsom, Jaap D van Buul, Timothy R D J Radstake, Dominique L Baeten, Paul P Tak, Kris A Reedquist and Samuel García.

in Rheumatology

May 2018; p ublished online February 2018 .

Journal Article. Subjects: Rheumatology. 5285 words.

Abstract

Objective

Class 3 semaphorins regulate diverse cellular processes relevant to the pathology of RA,...

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Functional Interaction between Matrix Metalloproteinase-3 and Semaphorin-3C during Cortical Axonal Growth and Guidance

B Gonthier, C Nasarre, L Roth, M Perraut, N Thomasset, G Roussel, D Aunis and D Bagnard.

in Cerebral Cortex

July 2007; p ublished online October 2006 .

Journal Article. Subjects: Neuroscience. 6164 words.

In the developing cortex, axons and dendrites extend progressively in response to environmental cues attracting or repelling growing processes. Recent evidence suggests the existence of a...

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