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semaphorin

Overview page. Subjects: Chemistry.

One of a class of proteins that act as guidance molecules during the development of nerve cells, immune cells, blood vessels, bone, and other tissues. There are several classes, some...

See overview in Oxford Index

semaphorin

Overview page. Subjects: Chemistry.

One of a class of proteins that act as guidance molecules during the development of nerve cells, immune cells, blood vessels, bone, and other tissues. There are several classes, some...

See overview in Oxford Index

semaphorin

Elizabeth Martin and Robert Hine.

in A Dictionary of Biology

January 2008; p ublished online January 2008 .

Reference Entry. Subjects: Biological Sciences. 124 words.

One of a class of proteins that act as guidance molecules during the development of nerve cells, immune cells, blood

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semaphorin

Edited by Robert Hine and Elizabeth Martin.

in A Dictionary of Biology

June 2016; p ublished online September 2015 .

Reference Entry. Subjects: Biological Sciences. 124 words.

One of a class of proteins that act as guidance molecules during the development of nerve cells, immune cells, blood

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semaphorins

John Lackie.

in A Dictionary of Biomedicine

January 2010; p ublished online January 2010 .

Reference Entry. Subjects: Clinical Medicine. 58 words.

A conserved family of proteins that inhibit the movement of the *nerve growth cone and influence the architecture of

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semaphorin

Edited by Richard Cammack, Teresa Atwood, Peter Campbell, Howard Parish, Anthony Smith, Frank Vella and John Stirling.

in Oxford Dictionary of Biochemistry and Molecular Biology

January 2006; p ublished online January 2008 .

Reference Entry. Subjects: Biochemistry. 96 words.

any of a family of secreted or membrane‐bound proteins (≈750 residues) that are expressed in various embryonal and adult tissues.

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Integration of Opposing Semaphorin Guidance Cues in Cortical Axons

Tina Ruediger, Geraldine Zimmer, Sandra Barchmann, Valérie Castellani, Dominique Bagnard and Jürgen Bolz.

in Cerebral Cortex

March 2013; p ublished online February 2012 .

Journal Article. Subjects: Neuroscience. 8153 words.

Previous work demonstrated that members of the semaphorin family, Sema3A and Sema3C, act as repulsive and attractive guidance signals, respectively, for cortical axons. During the...

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Semaphorin 5B Is a Novel Inhibitory Cue for Corticofugal Axons

Robyn L. M. Lett, Wenyan Wang and Timothy P. O'Connor.

in Cerebral Cortex

June 2009; p ublished online October 2008 .

Journal Article. Subjects: Neuroscience. 9778 words.

Neuronal connectivity is generated by the precise guidance of neuronal growth cones in response to the spatiotemporal distribution of molecular guidance cues in the developing embryo. Here...

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Semaphorin 3A and 3F: key players in myelin repair in multiple sclerosis?

Anna Williams, Gabrièle Piaton, Marie-Stéphane Aigrot, Aisha Belhadi, Marie Théaudin, Franziska Petermann, Jean-Léon Thomas, Bernard Zalc and Catherine Lubetzki.

in Brain

October 2007; p ublished online September 2007 .

Journal Article. Subjects: Neurology; Neuroscience. 6261 words.

The presence of demyelinated plaques in the central nervous system is the hallmark of multiple sclerosis (MS). Some plaques remyelinate but others do not, leaving permanent damage. The...

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Class 3 semaphorins influence oligodendrocyte precursor recruitment and remyelination in adult central nervous system

Gabrièle Piaton, Marie-Stéphane Aigrot, Anna Williams, Sarah Moyon, Vanja Tepavcevic, Imane Moutkine, Julien Gras, Katherine S. Matho, Alain Schmitt, Heidi Soellner, Andrea B. Huber, Philippe Ravassard and Catherine Lubetzki.

in Brain

April 2011; p ublished online March 2011 .

Journal Article. Subjects: Neurology; Neuroscience. 7166 words.

Oligodendrocyte precursor cells, which persist in the adult central nervous system, are the main source of central nervous system remyelinating cells. In multiple sclerosis, some...

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Axonal Surface Molecules Act in Combination with Semaphorin 3A during the Establishment of Corticothalamic Projections

Dominique Bagnard, Naura Chounlamountri, Andreas W. Püschel and Jürgen Bolz.

in Cerebral Cortex

March 2001; p ublished online March 2001 .

Journal Article. Subjects: Neuroscience. 7580 words.

Interactions between growing axons are considered to play important roles for the establishment of precise neuronal con- nections during the development of the nervous system. Here we used...

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