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steroid-hormone receptor

Overview page. Subjects: Chemistry.

Any intracellular receptor that binds steroid hormones and mediates their effects; the family also includes receptors for thyroid hormones, retinoids, and vitamin D. After the steroid...

See overview in Oxford Index

steroid‐hormone receptor

Edited by Richard Cammack, Teresa Atwood, Peter Campbell, Howard Parish, Anthony Smith, Frank Vella and John Stirling.

in Oxford Dictionary of Biochemistry and Molecular Biology

January 2006; p ublished online January 2008 .

Reference Entry. Subjects: Biochemistry. 67 words.

any intracellular receptor that binds steroid hormones and mediates their effects; the family also includes receptors for thyroid hormones, retinoids,

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steroid hormone receptor

Elizabeth Martin.

in The New Oxford Dictionary for Scientific Writers and Editors

January 2009; p ublished online January 2009 .

Reference Entry. Subjects: Language Reference. 56 words.

A nuclear cell receptor that is activated by a steroid hormone. There are several subclasses named according to the hormone

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steroid-hormone receptor

Overview page. Subjects: Chemistry.

Any intracellular receptor that binds steroid hormones and mediates their effects; the family also includes receptors for thyroid hormones, retinoids, and vitamin D. After the steroid...

See overview in Oxford Index

Steroid hormone receptors: an update

M. Beato and J. Klug.

in Human Reproduction Update

May 2000; p ublished online May 2000 .

Journal Article. Subjects: Critical Care; Reproductive Medicine. 0 words.

Steroid hormones (SHs) arelipophilic molecules derived from cholesterol and synthesized in the adrenal cortex (glucocorticoids, mineralocorticoids, and adrenal androgens), the testes...

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Steroid Hormone Receptors and Sex Differences in Behavior

Toni R. Pak and Robert J. Handa.

in Sex Differences in the Brain

December 2007; p ublished online January 2010 .

Chapter. Subjects: Neuroscience. 19217 words.

This chapter discusses how gonadal steroid hormones contribute to broad sex differences in the behavior of adult animals and the underlying molecular mechanisms that mediate hormone action....

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Deciphering Steroid Receptor Crosstalk in Hormone-Driven Cancers

Thu H Truong and Carol A Lange.

in Endocrinology

P ublished online October 2018 .

Journal Article. Subjects: Medicine and Health; Clinical Medicine; Endocrinology and Diabetes; Medical Oncology; Reproductive Medicine. 8926 words.

Abstract

Steroid hormone receptors (SRs) have a multitude of functions in human biology and disease progression. The SR family of related ligand-activated...

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Novel approaches for the study of vertebrate steroid hormone receptors

Satomi Kohno, Yoshinao Katsu, Taisen Iguchi and Louis J. Guillette.

in Integrative and Comparative Biology

October 2008; p ublished online August 2008 .

Journal Article. Subjects: Biological Sciences. 3402 words.

Steroid hormones are essential for the normal function of most organ systems in vertebrates. Reproductive activities in females and males, such as the differentiation, growth and...

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Hydroxysteroid dehydrogenases and pre‐receptor regulation of steroid hormone action

Trevor M. Penning.

in Human Reproduction Update

May 2003; p ublished online May 2003 .

Journal Article. Subjects: Critical Care; Reproductive Medicine. 0 words.

Steroid target tissues regulate the local level of steroid hormone that can bind and trans‐activate nuclear receptors (a process known as intracrine modulation). This pre‐receptor...

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Steroid hormone receptor expression and proliferation in rat mammary gland carcinomas induced by 2-amino-1-methyl-6-phenylimidazo[4,5-<i>b</i>]pyridine

Cunping Qiu, Liang Shan, Minshu Yu and Elizabeth G. Snyderwine.

in Carcinogenesis

April 2005; p ublished online April 2005 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 4773 words.

2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) is a mammary gland carcinogen present in the human diet. Herein, the expression of estrogen receptor alpha (ERα), estrogen receptor...

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PI3K/AKT pathway regulates phosphorylation of steroid receptors, hormone independence and tumor differentiation in breast cancer

Marina Riggio, María Laura Polo, Matías Blaustein, Alejandro Colman-Lerner, Isabel Lüthy, Claudia Lanari and Virginia Novaro.

in Carcinogenesis

March 2012; p ublished online December 2011 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 8102 words.

Using a model of medroxyprogesterone acetate (MPA)-induced mouse mammary tumors that transit through different stages of hormone dependence, we previously reported that the activation of...

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Are all high-grade breast cancers with no steroid receptor hormone expression alike? The special case of the medullary phenotype

L. Orlando, G. Renne, A. Rocca, G. Curigliano, M. Colleoni, G. Severi, G. Peruzzotti, S. Cinieri, G. Viale, G. Sanna and A. Goldhirsch.

in Annals of Oncology

July 2005; p ublished online April 2005 .

Journal Article. Subjects: Medical Oncology. 5095 words.

Background:: Medullary carcinoma (MC) of the breast is associated with favorable prognosis compared with other histological types, despite high nuclear grade, fast proliferation...

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Steroid Hormone Receptor Status of Mouse Mammary Stem Cells

Marie-Liesse Asselin-Labat, Mark Shackleton, John Stingl, François Vaillant, Natasha C. Forrest, Connie J. Eaves, Jane E. Visvader and Geoffrey J. Lindeman.

in JNCI: Journal of the National Cancer Institute

July 2006; p ublished online July 2006 .

Journal Article. Subjects: Medical Oncology. 2667 words.

The estrogen receptor α (ERα), progesterone receptor (PR), and erbB2 (Her2 in humans) are important prognostic markers of human breast cancer, and they are variably expressed in different...

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Safety of everolimus plus exemestane in patients with hormone-receptor–positive, HER2–negative locally advanced or metastatic breast cancer progressing on prior non-steroidal aromatase inhibitors: primary results of a phase IIIb, open-label, single-arm, expanded-access multicenter trial (BALLET)

G. Jerusalem, G. Mariani, E. M. Ciruelos, M. Martin, V. C. G. Tjan-Heijnen, P. Neven, J. G. Gavila, A. Michelotti, F. Montemurro, D. Generali, E. Simoncini, I. Lang, J. Mardiak, B. Naume, M. Camozzi, K. Lorizzo, S. Bianchetti and P. Conte.

in Annals of Oncology

September 2016; p ublished online June 2016 .

Journal Article. Subjects: Medical Oncology. 4091 words.

Background

This European phase IIIb, expanded-access multicenter trial evaluated the safety of EVE plus EXE in a patient population similar to BOLERO-2.

null...

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A critical review why assessment of steroid hormone receptors in breast cancer should be quantitative

O. Brouckaert, R. Paridaens, G. Floris, E. Rakha, K. Osborne and P. Neven.

in Annals of Oncology

January 2013; p ublished online July 2012 .

Journal Article. Subjects: Medical Oncology. 5123 words.

Steroid receptors have been around in the field of breast cancer for decades now. Still, controversy remains on how best to report steroid receptors. In this review, we will convince the...

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Re: Quantitative Association Between HER-2/neu and Steroid Hormone Receptors in Hormone Receptor-Positive Primary Breast Cancer

Frédérique Spyratos, Cécile Bouchet, Magali Ferrero-Poüs, Michèle Tubiana-Hulin and Kamel Hacène.

in JNCI: Journal of the National Cancer Institute

September 2003; p ublished online September 2003 .

Journal Article. Subjects: Medical Oncology. 933 words.

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RESPONSE: Re: Quantitative Association Between HER-2/neu and Steroid Hormone Receptors in Hormone Receptor-Positive Primary Breast Cancer

Gottfried Konecny, Mark Pegram and Dennis J. Slamon.

in JNCI: Journal of the National Cancer Institute

September 2003; p ublished online September 2003 .

Journal Article. Subjects: Medical Oncology. 757 words.

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Quantitative Association Between HER-2/neu and Steroid Hormone Receptors in Hormone Receptor-Positive Primary Breast Cancer

Gottfried Konecny, Giovanni Pauletti, Mark Pegram, Michael Untch, Sugandha Dandekar, Zuleima Aguilar, Cindy Wilson, Hong-Mei Rong, Ingo Bauerfeind, Margret Felber, He-Jing Wang, Malgorzata Beryt, Ram Seshadri, Herrmann Hepp and Dennis J. Slamon.

in JNCI: Journal of the National Cancer Institute

January 2003; p ublished online January 2003 .

Journal Article. Subjects: Medical Oncology. 10030 words.

Background: HER-2/neu, which encodes a receptor tyrosine kinase, is amplified and overexpressed in 20%–25% of human breast cancers. Such tumors are often resistant to hormone...

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The effect of transdermal oestradiol on bleeding pattern, hormonal profiles and sex steroid receptor distribution in the endometrium of Norplant users

Wisut Boonkasemsanti, Damrong Reinprayoon, Kamthorn Pruksananonda, Somchai Niruttisard, Surang Triratanachat, Smai Leepipatpaiboon and Pongsak Wannakrairot.

in Human Reproduction

October 1996 .

Journal Article. Subjects: Reproductive Medicine. 0 words.

The most common side-effect and reason for discontinuation with Norplant use is bleeding disturbance. The aim of this study was to investigate whether the 6 week application of a patch...

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39ORibociclib (RIB) + non-steroidal aromatase inhibitor (NSAI) + goserelin in premenopausal Asian women with hormone-receptor-positive (HR+), HER2-negative (HER2–) advanced breast cancer (ABC): Results from the randomized phase III MONALEESA-7 study

S-A Im, J Sohn, D Tripathy, L Chow, K S Lee, K H Jung, G Babu, Y-H Im, N El Saghir, M-C Liu, I Diaz-Padilla, J Alam, O Kong, M Miller and Y-S Lu.

in Annals of Oncology

November 2018; p ublished online November 2018 .

Journal Article. Subjects: Medical Oncology. 629 words.

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ER

Elizabeth Martin.

in The New Oxford Dictionary for Scientific Writers and Editors

January 2009; p ublished online January 2009 .

Reference Entry. Subjects: Language Reference. 13 words.

Abbrev. for 1 endoplasmic reticulum. 2 (o)estrogen receptor (see steroid hormone receptor).

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