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thyroperoxidase

Overview page. Subjects: Chemistry.

A glycosylated integral membrane protein and enzyme of the apical surface of thyroid follicle cells, involved in the formation of thyroxine from thyroglobulin. It contains 933 amino acids...

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thyroperoxidase

Overview page. Subjects: Chemistry.

A glycosylated integral membrane protein and enzyme of the apical surface of thyroid follicle cells, involved in the formation of thyroxine from thyroglobulin. It contains 933 amino acids...

See overview in Oxford Index

thyroperoxidase

Edited by Richard Cammack, Teresa Atwood, Peter Campbell, Howard Parish, Anthony Smith, Frank Vella and John Stirling.

in Oxford Dictionary of Biochemistry and Molecular Biology

January 2006; p ublished online January 2008 .

Reference Entry. Subjects: Biochemistry. 112 words.

a glycosylated integral membrane protein and enzyme of the apical surface of thyroid follicle cells, involved in the formation of

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Tiered High-Throughput Screening Approach to Identify Thyroperoxidase Inhibitors Within the ToxCast Phase I and II Chemical Libraries

Katie Paul Friedman, Eric D. Watt, Michael W. Hornung, Joan M. Hedge, Richard S. Judson, Kevin M. Crofton, Keith A. Houck and Steven O. Simmons.

in Toxicological Sciences

May 2016; p ublished online February 2016 .

Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 12784 words.

High-throughput screening for potential thyroid-disrupting chemicals requires a system of assays to capture multiple molecular-initiating events (MIEs) that converge on perturbed thyroid...

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iodotyrosine deiodinase

Overview page. Subjects: Chemistry.

An NADPH‐dependent flavoprotein enzyme that deiodinates monoiodotyrosine and diiodotyrosine derived from proteolytic degradation of thyroglobulin within lysosomes of thyroid follicle cells....

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organification defect

Overview page. Subjects: Chemistry.

A defect in the iodination of tyrosine residues in thyroglobulin and in their coupling to produce thyroid hormones. It causes a congenital form of hypothyroidism. The reactions are...

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diiodotyrosine

Overview page. Subjects: Chemistry.

abbr.: DIT; 3,5‐diiodotyrosine; iodogorgoic acid, 3,5‐diiodo‐4‐hydroxyphenylalanine, 2‐amino‐3‐(3,5‐diiodo‐4‐hydroxyphenyl)propanoic acid. Residues of the l enantiomer,...

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Thyroid autoimmunity and thyroid dysfunction in women with endometriosis

C.A. Petta, M.S. Arruda, D.E. Zantut-Wittmann and C.L. Benetti-Pinto.

in Human Reproduction

October 2007; p ublished online August 2007 .

Journal Article. Subjects: Reproductive Medicine. 2763 words.

BACKGROUND

Women with endometriosis may have higher rates of autoimmune disorders, including hypothyroidism. The objective of this study was to compare the...

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Increased risk of papillary thyroid cancer in systemic sclerosis associated with autoimmune thyroiditis

Alessandro Antonelli, Clodoveo Ferri, Silvia Martina Ferrari, Andrea Di Domenicantonio, Dilia Giuggioli, David Galleri, Paolo Miccoli and Poupak Fallahi.

in Rheumatology

March 2016; p ublished online September 2015 .

Journal Article. Subjects: Rheumatology. 2786 words.

Objectives. Patients with SSc have an increased risk of malignancy compared with the general population. Before now, no study has evaluated the risk of thyroid cancer (TC) in...

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Idiopathic primary ovarian insufficiency: a study of serial hormonal profiles to assess ovarian follicular activity

Deepti Goswami, Ayesha Arif, Alpana Saxena and Swaraj Batra.

in Human Reproduction

August 2011; p ublished online June 2011 .

Journal Article. Subjects: Reproductive Medicine. 3815 words.

BACKGROUND

Ovarian follicular activity in serial hormone profiles has been reported in up to 86% of patients with primary ovarian insufficiency (POI). In...

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Thyroid involvement in patients with overt HCV-related mixed cryoglobulinaemia

A. Antonelli, C. Ferri, P. Fallahi, D. Giuggioli, C. Nesti, G. Longombardo, P. Fadda, A. Pampana, M. Maccheroni and E. Ferrannini.

in QJM: An International Journal of Medicine

August 2004; p ublished online August 2004 .

Journal Article. Subjects: Medicine and Health. 4969 words.

Background: Mixed cryoglobulinaemia (MC), a systemic vasculitis associated with hepatitis C virus (HCV) infection in >90% of cases, is frequently complicated by multiple organ...

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