Journal Article

Drug-induced torsade de pointes: the perspectives of industry

J.T. Barbey

in European Heart Journal Supplements

Published on behalf of European Society of Cardiology

Volume 3, issue suppl_K, pages K112-K113
Published in print September 2001 | ISSN: 1520-765X
Published online September 2001 | e-ISSN: 1554-2815 | DOI: http://dx.doi.org/10.1016/S1520-765X(01)90015-X
Drug-induced torsade de pointes: the perspectives of industry

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In 1996 the Committee for Proprietary Medicinal Products published their ‘Points to consider’ which have been used as unofficial guidelines by drug companies developing new pharmacologic compounds. Recommendaitons endorsed by the CPMP regarding hand measurement of the QT interval, QT dispersion, the Bazett QT interval correction for heart rate and the use of signal values for QTc changes compared to baseline are discussed in this paper.

Keywords: ‘Points to consider’; QT interval measurements

Journal Article.  0 words. 

Subjects: Cardiovascular Medicine

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