Journal Article

Cardiac morphology and physiology predisposing to thrombus formation

D. Horstkotte, D. Hering, L. Faber and C. Piper

in European Heart Journal Supplements

Published on behalf of European Society of Cardiology

Volume 3, issue suppl_Q, pages Q8-Q11
Published in print December 2001 | ISSN: 1520-765X
Published online December 2001 | e-ISSN: 1554-2815 | DOI:
Cardiac morphology and physiology predisposing to thrombus formation

Show Summary Details


Cardiogenic neurologic embolism accounts for approximately 15–20% of stroke cases. Various diseases and therapeutic interventions may predispose a patient to intra-cardiac thrombus formation and subsequent embolism. General risk factors for intra-cardiac thrombus include an abnormal endocardium, loss of atrial contraction, arrhythmias, cardiac chamber dilatation and impaired left ventricular function. The present review addresses the pathophysiological mechanisms that underlie these risk factors and their relationship to thrombus formation. In addition, the phenomenon of spontaneous echo contrast is reviewed, as is its usefulness in identifying patients who are at risk for thromboembolic complications.

Keywords: Cardiac embolism; spontaneous echo contrast; thromboembolic complications; thrombosis

Journal Article.  0 words. 

Subjects: Cardiovascular Medicine

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