Journal Article

Management strategies in hypertrophic cardiomyopathy: influence of age and morphology

W.J. McKenna, S. Sharma and P.M. Elliott

in European Heart Journal Supplements

Published on behalf of European Society of Cardiology

Volume 3, issue suppl_L, pages L10-L14
Published in print October 2001 | ISSN: 1520-765X
Published online October 2001 | e-ISSN: 1554-2815 | DOI:
Management strategies in hypertrophic cardiomyopathy: influence of age and morphology

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Management in hypertrophic cardiomyopathy is aimed at improving symptoms and exercise capacity and preventing complications, particularly sudden death. The strategy for management of symptoms is to identify potentially important mechanisms at which treatment can be targeted. Assessment is feasible with non-invasive evaluation. All patients with hypertrophic cardiomyopathy should undergo risk assessment for sudden death, regardless of their symptomatic, morphological and haemodynamic status. Recent prospective studies have examined five risk markers: family history of sudden death (two or more members aged <45 years), unexplained syncope, non-sustained ventricular tachycardia on Holler monitoring, abnormal exercise blood pressure response and severe left ventricular hypertrophy (≥3 cm). The majority of patients had none of these risk factors and did not die suddenly. Annual sudden death rates were at least 2% among patients with two or more of these risk markers, which warrants consideration of prophylactic treatment (amiodarone, implantable cardioverter-defibrillator) in such patients.

Keywords: children; hypertrophic cardiomyopathy; hypertrophy; infants; sudden death

Journal Article.  0 words. 

Subjects: Cardiovascular Medicine

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